When temperatures spike, California redwoods slow down photosynthesis, new research has found. This finding has serious implications for the long-term survival of the iconic trees in a warming world, and their role in storing carbon from the atmosphere.

California redwood (Sequoia sempervirens) forests are among the largest aboveground carbon stores on the planet. These towering trees are native to central and northern California, and evolved to take advantage of the region's historically mild weather. In recent decades, their range has contracted significantly. But climate change is threatening the health and function of these forests.

The region has seen significant warming in recent decades, and faces more frequent extreme heat days, with temperatures spiking above 100 degrees Fahrenheit (37 degrees Celsius). Now, in a new study, published Sept. 22 in the journal JGR Biogeosciences, a team of researchers has shown that California's renowned redwoods are struggling to photosynthesize in the heat.

Photosynthesis is the process used by plants, algae and some bacteria to turn sunlight into energy. It chemically converts carbon dioxide and water into sugars and oxygen.

"These trees adapted to grow in really temperate environments, so no one had really looked at the impact of heat on photosynthesis," study first author Lily Klinek, a doctoral candidate in the Plant Optics Lab at the University of California, Davis, told Live Science.

From 2022 to 2024, Klinek and colleagues measured how the leaves of redwoods in Garcia River Forest in Mendocino County responded to the heat. Once or twice a month, the researchers took three different California redwood leaf samples and measured their fluorescence and temperature.

A plant's molecules can use absorbed light in three ways: for photosynthesis, dissipated as heat, or reflected as light (florescence). Fluorescence is a proxy measurement to understand photosynthesis in the plant, Klinek said.

The researchers wrapped a fourth leaf in tinfoil for 20 minutes to put it in a state of "rest" before taking the same measurements. "When they're in a state of rest, we expose them to a pulse of light that’s in the wavelength they would use for photosynthesis to see what would be their maximum photosynthetic rate," Klinek said.

They found that on hot days, the leaves exposed to sunlight were up to 18 degrees Fahrenheit (10 degrees Celsius) hotter than the air temperature. "That's a huge difference and indicates that the leaves are stressed to the point where they can't thermoregulate effectively," Klinek said.

Many plants' leaves manage their temperature and photosynthesis by opening or closing their stomata, which are tiny pores on their surface. These stomata (from the Greek word for mouth) regulate the amount of carbon dioxide entering the plant, and how much oxygen and water vapor it releases. Lower carbon dioxide intake leads to reduced photosynthesis, meaning the plant has less energy.

The large differences between air and redwood leaf temperatures suggest that the leaves had closed their stomata to avoid losing water from evaporation during hot conditions and consequently overheated, Klinek said.

To further investigate the impact of heat on leaf physiology, the researchers took California redwood leaf samples back to the laboratory and exposed them to a range of temperatures while they were in water. Despite their access to water, the leaves still photosynthesized less as they got hotter, even though their stomata were open, Klinek said.

This shows that heat imposes direct limitations on redwood photosynthetical capacity, rather than indirectly decreasing that capacity by causing stomatal closure, the researchers wrote. The finding indicates that redwoods' ability to photosynthesise and store carbon will decrease as temperatures rise.

​​"It is not only stomatal closure that is causing reduced photosynthesis," Lucy Rowland, an ecologist at the University of Exeter in the U.K. who was not involved in the study, told Live Science in an email. "These trees are already suffering from the direct effects of heat on their photosynthetic systems."

The finding has serious implications for the future of redwoods and similar plants. "The points at which this damage becomes irreversible remains really poorly understood, but is something which is really essential to understand if we want to predict how our future climate is going to impact plants," she said.

The next step in Klinek's research is to move beyond leaf physiology to understand these thresholds on the trees and their ecosystems as a whole.

"We're not sure to what extent the effect that we saw is a reversible stress response and if they are sustaining damage from this constant stress," she said. Researchers need more data to "really get a better sense, beyond the leaf scale, how these ecosystems are responding to heat and drought," she added.

Recent research challenges a long-standing idea about how the brain develops: Rather than arising from a single source, the brain may emerge from two distinct populations of cells, the study finds.

"The brain appears as one organ," said study co-author Kyle Loh, an associate professor of developmental biology at Stanford University. "However, we discovered that the front part of the brain and the back part of the brain come from different sources, which are pushed together to create the appearance of a single organ," Loh told Live Science in an email.

The findings, published in September in the journal Nature Neuroscience, not only challenge established models of how the brain forms but may also explain why researchers have struggled to grow certain types of brain cells in the laboratory. The scientists say the work could offer new ways to investigate diseases that affect the brainstem, the "stalk" that connects the brain to the spinal cord.

Two developmental journeys

The human brain is divided into three main regions — called the forebrain, midbrain and hindbrain — that perform different but interconnected functions.

The forebrain, which includes the cerebral hemispheres, is involved in higher-level cognitive processes, such as language, planning and abstract thinking. The midbrain, the uppermost part of the brainstem, connects the forebrain and the hindbrain and acts as a key relay center for sensory information and movement control. The hindbrain — which includes the bottom of the brainstem, along with other structures — also helps to coordinate movement, as well as regulate essential functions such as breathing, sleep and heart rate.

Historically, the hindbrain has been difficult to study. One reason is that scientists have faced persistent challenges in generating functional hindbrain neurons in laboratory conditions.

To help understand why, Loh and his team looked at the early stages of embryonic development in lab mice. They focused on gastrulation, the point when cells begin to organize into structures that will later form different organs. The researchers identified two distinct populations of immature cells that would go on to give rise to nervous system tissue, including the brain.

One cell population expressed a gene called Otx2, which helps to direct the early development of the forebrain and midbrain. The second group of cells expressed the gene Gbx2, which is involved in the development of the midbrain and hindbrain.

The functions of these genes were already known, but their distinct expression in these two groups of cells was revealed by the new research. The cell populations remained distinct as they developed into full-fledged nervous tissue, rather than overlapping.

The team also examined chromatin, the molecular structure that packages DNA tightly inside the nucleus and helps regulate which genes a cell can use. The two cell populations show different chromatin configurations, the team found, which further supports the idea that they follow separate developmental pathways.

That may help to explain why scientists' attempts to grow hindbrain neurons have been largely unsuccessful.

"Previous attempts to make hindbrain neurons likely tried to coax forebrain and midbrain progenitors into hindbrain cells, which our study shows is not possible," study co-author Rayyan Jokhai, a graduate student in Loh's lab, said in a statement.

Why it matters

Using the information uncovered in their experiments, the researchers successfully guided human stem cells to transform into functional hindbrain motor neurons, which are involved in controlling movement. Specifically, these cells produced proteins characteristic of the hard-to-grow hindbrain regions that help control muscles of the face and those involved in swallowing.

In several neurological diseases, including spinal muscular atrophy and amyotrophic lateral sclerosis, motor neurons deteriorate and affected patients can lose their ability to swallow, speak and breathe independently.

"We cannot sample living motor neurons from a patient's hindbrain to watch how these diseases attack these neurons," Loh said. "Growing these hindbrain motor neurons in a dish gives us a way to investigate these diseases." Looking forward, the team aims to use their findings to study these diseases and pinpoint new treatments.

The new findings could also reveal something fundamental about the evolution of vertebrate animals.

The study authors investigated whether the two developmental pathways were unique to humans or reflected a much older evolutionary arrangement. They turned to previously published data on other species — including macaques (Macaca), zebrafish (Danio rerio) and chickens (Gallus gallus domesticus) — and again found two distinct cell populations expressing the two key genes.

And even in acorn worms — a marine invertebrate whose evolution diverged from vertebrates about 550 million years ago — they again found these two distinct groups of cells.

"The Stanford discovery establishes that the deep ancestry of the vertebrate brain is fundamentally modular," said Anna Di Cosmo, a professor of biology at the University of Naples Federico II in Italy who wasn't involved with the study. "The developmental separation between the anterior lineage (forebrain/midbrain) and the posterior lineage (hindbrain) is traceably ancient," Cosmo told Live Science in an email.

Loh's team speculates that these developmental trajectories seen in the womb may suggest that the two cell populations once belonged to two separate nervous systems. "Later in evolution, these two nervous systems may have been pushed together to give rise to the appearance of one integrated brain," Loh said.

However, the study doesn't reveal exactly when the two pathways arose or establish how they integrated. "It is important to emphasize that this is only an idea, and it might change as scientists learn more," Loh said.

See how much you know about the most complex organ in the human body with our brain quiz!

A new 4,300-mile (7,000-kilometer) undersea fiber cable will shuttle data between the U.S. and France at breakneck speeds of up to 1 million gigabits per second (Gbps) — enough to move around 125 terabytes of data every second, or roughly 25,000 HD movies, each 5 gigabytes large. The cable, called Petal, will be funded and operated by Facebook and Instagram parent company Meta.

When it comes online in 2029, the ocean-spanning cable will be the first to deliver petabit capacity — double the capacity of existing subsea cables of this length — across transoceanic distances, Meta representatives said in a statement. That's enough to allow 75% of the world's population to stream music at once.

Petal will also be the first commercial subsea cable system to use multi-core fiber technology, according to the statement. Whereas conventional fiber strands typically contain a single core, each of Petal's fiber strands will contain two cores that carry optical signals in opposite directions, allowing a single strand to provide the capacity that would conventionally require a pair of single-core fibers.

Each fiber strand is roughly as thick as a human hair, measuring just 125 micrometers in diameter. Petal will contain 24 pairs of dual-core fibers, giving it 96 individual fiber cores in total and enabling it to carry as much data as 48 conventional fiber pairs, Meta engineers said.

Japanese technology company NEC will be responsible for the overall design and construction of Petal, while Sumitomo Electric will provide the fiber itself.

"Achieving petabit-per-second capacity across a transoceanic submarine system represents a major technological milestone in the history of global telecommunications," Eduardo Mateo, chief strategy officer of the Submarine Networks Division at NEC, said in the statement.

Bedrock of the internet

Subsea cables are among the most critical layers of internet infrastructure, carrying around 99% of the world's internet traffic, according to the International Telecommunication Union, the United Nations ​agency for digital technologies.

Installing thousands of miles of fragile glass cable on the ocean floor is an engineering feat in itself. Equally challenging is ensuring that these cables can carry the tiny pulses of infrared light that transport fiber-optic data across such huge distances without impacting performance.

This is typically achieved through repeaters — amplifiers installed at regular intervals along the cable that use lasers to boost the optical signals.

A 4,300-mile subsea cable typically needs about 100 of these repeaters to amplify the signals along its length, Meta representatives said.

Petal will incorporate something called "fan-in/fan-out" technology. As each two-core fiber strand enters a repeater, an optical interface routes the signal from each core into a separate single-core fiber strand so that each can be amplified independently. The amplified signals are then routed back into the two cores of the dual-core fiber before continuing along the cable.

Combined with its dual-core fiber, this feat of signal engineering will enable Petal to double its data-carrying capacity without requiring a proportional increase in power, Meta representatives said.

Petal is one of many subsea cable investments by Meta in recent years, including Marea in 2018, Amitie in 2023 and Anjana in 2025. Marea, the company's first transatlantic fiber instalment, supports 192 Tbps, meaning Petal will offer more than five times that capacity.

Archaeologists digging at a 13,800-year-old site in interior Alaska have unearthed thousands of artifacts and fossils, including what may be the bones of the earliest domesticated dogs in the Americas, the earliest needles and dwellings in the Western Hemisphere, and stone tools that reveal cultural connections across the Bering Land Bridge.

At a site called Shégˊ Xdaltthˊíˊ (which means "They Were There" in the Alaska Native Athabascan language), about 34 miles (55 kilometers) southeast of Fairbanks, archaeologists have excavated an encampment that some of the first people to settle in North America used off and on for a millennium.

Shégˊ Xdaltthˊíˊ is located in eastern Beringia, the geographical region that connected northeast Asia and northwest North America during the last ice age. The most recent archaeological and genetic studies suggest that the ancestors of today's Indigenous Americans entered the continent around 21,000 years ago. But since Beringian sites are often the remains of small seasonal hunting camps and are scattered across a large geographic area, much is still unknown about the earliest people who called the Western Hemisphere home.

"I expected we'd find hunting tools and knapping [stone tool making] debris surrounding a hearth or two, but I had no idea that we'd stumble into a base camp with tens of thousands of artifacts," study first author Kelly Graf, an archaeologist at the University of Kansas, told Live Science in an email. "It was a total surprise!"

In a study published Wednesday (Oct. 14) in the journal Science Advances, Graf and co-authors detailed their discoveries at Shégˊ Xdaltthˊíˊ, focusing on the earliest occupation, which occurred around 13,800 years ago, as evidence of people "settling in" to their new territory.

The researchers found a hearth, a small pit, and a dirt stain where a wooden post had once stood, likely the remains of a lean-to or early tent house. Additionally, the archaeologists unearthed stone tools, bone needles and a pendant made from an antler. Nearby, they found an earth oven, which was full of charcoal and animal bones and was likely used to slow-cook meat for a large family group.

"The complex feature at Shégˊ Xdaltthˊíˊ represents the earliest potential case of a habitation structure in North America," the researchers wrote in the study. "Early Alaskans knew their surroundings well."

Cross-cultural links

The archaeologists were also surprised by the stone tools recovered at Shégˊ Xdaltthˊíˊ because they are distinctively shaped and unique to central Alaska. Known as diamond-shaped hafted bifaces, the tools were crafted from rhyolite and basalt and are similar to those typically found much farther west in Beringia, in modern-day northern Siberia. Additionally, obsidian artifacts discovered at Shégˊ Xdaltthˊíˊ reveal that people brought the volcanic rock to the site from a geological source hundreds of miles to the northwest.

Bones from more than a dozen wolf-like animals suggest a further connection to Asia, according to the researchers. An analysis of the jaw of one of the animals showed that it was not from a dire wolf (Aenocyon dirus) or from a Pleistocene Beringian or gray wolf (Canis lupus sp.) but rather a population of wolf-like animals unique to central Alaska. Current genetic evidence suggests that early domesticated dogs in North America came from Siberian wolves. The timing and geographical location of Shégˊ Xdaltthˊíˊ provides circumstantial evidence that the people may have been dog owners.

"Like humans, potentially, the canids of Shégˊ Xdaltthˊíˊ and other early Alaskan sites were recent immigrants from Asian Beringia," the researchers wrote.

Although Shégˊ Xdaltthˊíˊ reveals a relationship with sites in Asia, there is also evidence of connections with early American sites south of the Canadian ice sheets, according to the study.

One clue to these connections is the presence of bone artifacts in a sewing kit. The archaeologists found eight bone needle fragments at Shégˊ Xdaltthˊíˊ. Previously, the only recovered eyed needles had come from Paleoindian sites in temperate North America. Therefore, the needles from Shégˊ Xdaltthˊíˊ are the oldest needles ever discovered in the Western Hemisphere, and they reveal connections with sites farther south, according to the study.

Another clue is the pendant, which was crafted from antler. The pendant had a hole drilled at one end and was fashioned into a point at the other end. This piece of ancient jewelry is similar to personal adornment items found farther south in North America.

"The co-occurrence of these cultural features at the single site of Shégˊ Xdaltthˊíˊ is truly notable," the researchers wrote, and they "highlight the strong cultural connection between early Beringians and Americans."

It is still unclear whether the people at Shégˊ Xdaltthˊíˊ were traveling to make these connections. "It would be hard to pin down whether or not they were moving back and forth during a lifetime, but at least we can say there is a connection," Graf said.

Further work in Beringia is needed

Future excavations in Beringia could help archaeologists learn more about the earliest people in the Americas, according to Graf. "Alaska is a big place and so remote, so there are really just a few small areas that have been intensively investigated," she said.

Spencer Pelton, an archaeologist at the University of Wyoming who was not involved in the research, wrote in an accompanying perspective published in the journal Science Advances that early Indigenous sites in Beringia are key to understanding the peopling of the Americas.

"Shégˊ Xdaltthˊíˊ is remarkable because it is the oldest site in the Americas containing a large and rich assemblage of features, artifacts, and faunal refuse indicative of prolonged residential occupation, providing an unprecedented glimpse into the lives of North America's first residents," Pelton wrote.

Graf is already planning future archaeological excavations in the area. "We're hoping to bring some younger Alaska Native folks out with us in the coming summers," she said, as incorporating local knowledge is important to the project. "Two of our co-authors are elders from Alaska Native corporations nearest to the site," she said. Elders named the Shégˊ Xdaltthˊíˊ site and have visited it to discuss where to excavate and what the archaeologists might find.

There is much left to learn about what was happening in Beringia 14,000 years ago, the researchers wrote, particularly since there are currently only two archaeological sites — including the 24,000-year-old Bluefish Caves site in the Yukon — that suggest humans were settling in Beringia considerably earlier.

How much do you know about the first people to reach the Americas? Find out with our First Americans quiz!

"Necklaces" of ultracold atoms have provided new evidence to support a nearly 100-year-old quantum theory.

In 1931, physicists were trying to use quantum mechanics to explain why some materials are magnetic. Then, a young physicist named Hans Bethe looked at a single row of electrons. Each electron's spin can point up or down. Bethe worked out the math for how such a row behaves and found that if a few spins in the row flip, they can stick together and travel down the row as a single unit.

Decades later, physicists found that Bethe's method also works for larger particles moving along a line, such as atoms. If those particles attract each other, the math predicts they will bind into clusters called Bethe strings.

Now, physicists have found evidence of these clusters in a line of ultracold atoms. The findings were published Aug. 29 in the journal Nature Communications.

The discovery may not create new gadgets, but it addresses a fundamental mystery in physics. Everything around us, from magnets to phone chips, consists of countless interacting particles. This makes their behavior difficult to predict. Ultracold atoms serve as a clear and adjustable way to study these complex systems.

A "necklace" of atoms

Researchers have spotted small Bethe strings before, in magnetic crystals and superconducting quantum circuits ‪— but those experiments captured strings one at a time.

Theory predicts that crowds of strings, in many sizes, can change how an entire system behaves, and studying that idea requires making many strings at once. That has been hard to do with atoms. Atoms that attract each other usually collapse into a clump. But this time, the team appears to have made many strings of different sizes at once, including some with more than six atoms.

It's tricky to get atoms to attract each other. In three dimensions, a gas made of attracting atoms tends to collapse as the atoms clump together and form molecules. That process releases energy that kicks atoms out of the experiment, so the gas quickly collapses and disappears. But when they're in a single line, the atoms behave differently.

"They are really a bit like pearls on a string, right? Like on a necklace, they cannot go past," study co-author Hanns-Christoph Nägerl, an experimental physicist at the University of Innsbruck, told Live Science. "In 3D, everything would collapse. But in 1D, it does not collapse."

To build their "necklaces," the team started with tens of thousands of cesium atoms cooled into a Bose-Einstein condensate ‪— a state of matter in which atoms chilled to near absolute zero share a single quantum state. Laser beams then divided the condensate into thousands of thin tubes, each of which held up to a few dozen atoms in a line.

At first, the atoms repelled each other. The researchers used a magnetic field to gradually turn that repulsion down to zero, and then turned it into attraction.

The team couldn't see the strings directly. Instead, they let the atoms go and measured how fast the cloud spread. When the atoms could expand only along their tubes, any strings stayed intact. When the atoms were freed in all three dimensions, the strings broke apart and released their binding energy as motion. The researchers found that the 3D clouds spread with about three times as much energy as the one-dimensional ones did.

From that difference, the team estimated how tightly the atoms had been bound. The answer pointed to strings of at least six atoms. The measurements also closely matched predictions from a theory called generalized hydrodynamics, which describes a gas like this one as a fluid made of many kinds of particles, including strings of different sizes. It also tracks how each kind flows over time rather than following every atom.

Nägerl was careful not to call this proof. "That some theory fits to your data is not a proof that something exists," he said; it's just more evidence to support it.

A short-lived state

The strings likely don't survive long. Up close, the atoms still feel the three-dimensional world, and the strings eventually decay into ordinary cesium molecules. In the coldest runs, the team lost about 40% of the atoms.

"Transiently you create these Bethe string states," Nägerl said. "But I don't think they are long-lived."

He has an idea for future experiments. Physicists recently learned to shield ultracold molecules with microwaves, which keeps the molecules from colliding at close range. Strings made from shielded molecules might last long enough to be studied directly. But Nägerl stressed that the idea is untested. "I've had nobody do a theory check on my claims now, but I think intuitively this should work," he said.

Another option is quantum gas microscopy, which images atoms one at a time and could offer more direct evidence of individual strings.

For Nägerl, Bethe strings are one step in understanding how quantum systems with many particles behave and settle down over time. His long-term goal is an experiment in which physicists control both how every particle moves and how its spin flips, letting them assemble model materials piece by piece, "like a LEGO type," he said. His team has begun the next step: using lasers to control the spins of the atoms in its one-dimensional gas. He described Bethe strings as "a little diversion." But because the strings form whenever the atoms attract, they can't be ignored.

A fossil that sat in a museum collection for over a century is a previously unknown species of predatory dinosaur, researchers have found. The discovery could help scientists solve a longstanding mystery about how some of the Cretaceous period's most formidable hunters spread around the globe.

The dinosaur lived on what is now the Isle of Wight in southern England about 120 million years ago. It belonged to a group of two-legged carnivores called megaraptors, which are related to tyrannosaurs. But unlike tyrannousars, megaraptors are thought to have relied on their powerful arms and large curved claws to attack prey and defend themselves.

The newly identified species was described in an Oct. 14 study in the journal Royal Society Open Science. It is the first megaraptor identified in Europe, filling an important gap in the fossil record of a group whose evolutionary history remains poorly understood.

"It is a real mystery that this fossil was overlooked for so long, sitting in a drawer for nearly 100 years," study first author Cassius Morrison, a researcher in the Department of Earth Sciences at University College London (UCL) said in a statement. "Lots of bones are found on the Isle of Wight — who knows what else is waiting to be discovered."

Unconquered female warrior dinosaur

The discovery of the megaraptor began in 1924, when an amateur fossil collector discovered a dinosaur skull fragment on the Isle of Wight. The specimen eventually entered the collections of London's Natural History Museum, but it was largely forgotten.

Recently, researchers revisited the fossil as part of a study on dinosaur braincases. To identify the animal, the researchers used micro-CT scanning to examine the fossil's internal structure and build detailed 3D digital models of the space that once held the dinosaur's brain.

The researchers then compared the animal's anatomy with that of other meat-eating dinosaurs, including tyrannosaurs, spinosaurs and other theropods (the group of two-legged, mostly meat-eating dinosaurs). Several features differentiated the unknown specimen, including an almost oval opening where the spinal cord entered the skull and an unusual, hourglass-shaped ridge at the back of the braincase.

Computer-based evolutionary analyses placed the fossils within the Megaraptora family tree, supporting the idea that the skull represented a never-before-seen species. The researchers named the dinosaur Invictibellatrix amberina, combining the Latin words "unconquered" and "female warrior" for the genus name, while amberina refers to amber found in the rocks associated with the fossil.

Megaraptors lived between roughly 125 million and 66 million years ago and varied considerably in size. While early members were relatively small, some later species became enormous predators. Maip macrothorax, discovered in Argentina, may have reached up to 33 feet (10 meters) long and weighed as much as an elephant. Based on comparisons with related dinosaurs, I. amberina was much smaller, likely around 10 to 13 feet (3 to 4 m) long and standing roughly 5 feet (1.5 m) tall. The researchers estimated it weighed around 440 to 660 pounds (200 to 300 kilograms), making it one of the smallest known megaraptors.

"It was not the apex predator of its time, but for humans this dinosaur would have been more dangerous than a T. rex," Morrison said. "We would have been perfectly sized prey, about a third of their body weight. They definitely would have chased us."

Although the newly described fossil doesn't preserve the animal's arms or claws, its closest relative suggests that its claws may have measured around 4 to 8 inches (10 to 20 centimeters) long. The researchers also suggested I. amberina may have been feathered, though that feature can't be determined directly from the specimen.

A missing link in the dinosaurs' globetrotting

Scientists have long suspected that megaraptors originated in Asia before spreading to other parts of the world, eventually becoming the dominant predators across the southern supercontinent Gondwana, which included present-day Africa, South America and Antarctica. But a lack of European fossils left an important gap in verifying this migration route.

The new study's evolutionary models suggest that I. amberina descended from Asian megaraptors that dispersed into Europe around 130 million years ago. From there, members of the group may have moved through what is now Africa and further into Gondwana via temporary landbridges and temporary land connections across the shallow Tethys Ocean.

"This new species is the first proof we have that megaraptorans were also present in Europe and that they reached Gondwana this way rather than island-hopping further south," study co-author Charlie Scherer, a doctoral student at UCL Earth Sciences, said in the statement.

However, the specific route these animals took over millions of years is still unknown. The researchers also cannot yet explain why megaraptors disappeared from northern areas, but changes in climate or competition with other predatory dinosaurs may have contributed. More research on other megaraptor fossils like I. amberina could help uncover more clues.

"Work like this shows the exceptional value of working with historical museum collections where there are still many discoveries to be made," study co-author Paul Barrett, a researcher of dinosaur evolution at the Natural History Museum in London, said in the statement.

Stellar cores called white dwarfs come in an astonishing array of colors, including what scientists say is the first known green star and the reddest star ever found, new research reveals.

A white dwarf star is the dense, cooling core that remains after a low- to medium-mass star runs out of fuel. The new study, published Thursday (Oct. 15) in the journal RAS Techniques and Instruments, shows that white dwarfs come in far more colors than their name suggests.

White dwarf stars got their moniker because the first known examples glowed in either white or pale blue. The new study, however, suggests that "white" dwarfs also emit visible-light colors like pink, green, cyan, purple and yellow.

"Most stars, including most white dwarfs, behave like 'perfect radiators,' so their colour is set almost entirely by temperature. But nobody had really looked into what else might be possible for white dwarfs," Mark Hollands, an astronomer at the University of Warwick in the U.K. and first author of the study, said in a statement. "It turns out these incredibly dense stars can produce colours nobody expected, and some of them genuinely surprised me."

The variety of colors is possible due to white dwarfs' densities compared with main-sequence stars, the study suggests. Cooler white dwarfs have a density of about 1 gram per cubic centimeter, much like flowing water on Earth. The density of these white dwarfs is also millions of times denser than the sun's visible surface, or photosphere, leading to unusual conditions.

"Any trace elements that may be present, such as carbon, calcium and sodium, interact with the surrounding dense helium plasma and absorb light across a wider range of colours than they would at lower densities," the researchers said in a statement. "This shifts a star's colour away from the orange, white and blue [typical] of a perfect radiator."

White dwarfs are far away and small, making it difficult to verify their color. So, in the new study, astronomers inferred the colors using spectra, the distinctive chemical fingerprints produced by stars' light. The team analyzed the spectra within a model of color vision that the human eye can see, making the color pop out.

Scientists found that carbon-rich white dwarfs tend to be purple or pink, while those that contain debris from asteroids or comets are usually yellower. Cyan or pale-blue white dwarfs occur when hydrogen and helium molecules strike each other in very dense atmospheres.

The team also discovered WD J1330+6435 — a green star that contains rocky material. The green comes from the additional elements of calcium, lithium and sodium in the star's atmosphere, creating a unique "chartreuse green appearance" that would be visible to the human eye, if we could see it up close.

"The traces of sodium in the atmosphere of this white dwarf absorb the orange part of the spectrum, leaving behind a ghostly green glow," Hollands explained, adding that the one-of-a-kind green star "feels like something out of science fiction." The team also discovered what is likely the reddest star ever found. This white dwarf, called WD J1011+2845, is located roughly 48 light-years from our planet. It has carbon closer to its surface — because the element is being lifted from the interior, due to strong convection currents — that is bending the star's light. This process is making a "deep salmon-pink glow" because the carbon molecules are obstructing the star's other wavelengths.

Overall, in the sample of stars studied — 151 white dwarfs within 65 light-years of Earth — about 1 in 30 white dwarfs glowed in a color other than white. This could mean there are far more colorful stellar remnants littering the universe than anyone anticipated.

While working on his land in a village in northern Egypt, a man made an astonishing discovery: the remains of two massive statues of Ramesses II.

The man, Khaled el-Shahat, immediately notified the Egyptian Ministry of Tourism and Antiquities, which sent a team to the village of Behbeit El Hagar to excavate and study the statues, the ministry said in a translated statement.

Ramesses II had one of the longest reigns in Egypt's history, ruling from around 1279 to 1213 B.C. During his 66 years in power, Egypt controlled an empire that stretched as far northeast as modern-day Syria. He initiated many building projects throughout the empire, and numerous Ramesses II statues have been found throughout Egypt.

Archaeologists had previously found architectural fragments bearing the name of Ramesses II at Behbeit El Hagar, which is known for its temple dedicated to Isis, a goddess associated with healing and magic, said Mahmoud Emam, an Egyptologist at Cairo University who has worked on remains from the site but was not involved with the recent excavation. He noted that the newly found statues were unearthed on the western side of the temple complex.

"Strong Bull"

Both of the newfound statues were once larger than life, with the bigger one likely standing nearly 28 feet (8.5 meters) tall when it was originally built. However, most of what remains is its head, which is 5.2 feet (1.6 m) tall and depicts the pharaoh wearing the double crown of Upper and Lower Egypt.

Part of this large statue's back pillar has a hieroglyphic inscription that gives the pharaoh's "Horus" name: Hor-Ka-Nakht-Mery-Maat. This name means "Strong Bull, Beloved of Right, Truth," Joyce Tyldesley, a professor emeritus of Egyptology at the University of Manchester in the U.K., wrote in her book "Ramesses: Egypt's Greatest Pharaoh" (Penguin Books, 2001). In Egypt, it was common for pharaohs to have several alternate names with a Horus name, given in honor of the sky god Horus.

The second statue, which stands about 7.9 feet (2.4 m), also likely depicts Ramesses II, the statement said. The king is shown wearing the "Nemes" headdress, a type of striped headcloth that pharaohs wore, the Egypt Exploration Society notes on its website.

Near this statue is a block of pink granite with two hieroglyphic inscriptions that name Ramesses II and describe him as "King of Upper and Lower Egypt" and the "Son of Ra," an ancient Egyptian sun god, the statement said.

Previous Ramesses II finds

The new finds add more evidence that Ramesses II was heavily invested in the site.

Previous discoveries include two architectural fragments bearing the name of Ramesses II near the Isis temple at Behbeit El Hagar, Emam and his colleagues reported in a 2017 paper. One is believed to be from the upper part of a statue, and another seems to originate from the upper part of a wall.

"We concluded that Ramesses II had undertaken major building works at the temple and recommended further archaeological investigations to shed more light on the early history of the site," Emam said. He noted that the site is threatened by urban growth and that excavation work should be carried out at the temple.

Live Science reached out to the team but did not hear back by the time of publication.

Are you a fan of mummies and hieroglyphs? Find out with our ancient Egypt quiz!

A Neanderthal who was buried 75,000 years ago in Shanidar Cave in Iraq died from a wooden spear straight through the chest, archaeologists have revealed.

While it's impossible to know exactly what happened, the violence may have been a targeted hit.

"The position of the wound and the force required to push it right through the Neanderthal's body bear the hallmarks of an intended kill shot directed towards the heart," study first author Emma Pomeroy, a paleoanthropologist at the University of Cambridge, said in a statement.

In a study published Thursday (Oct. 15) in the journal Scientific Reports, Pomeroy and co-authors analyzed the bones of Shanidar A, a Neanderthal who died violently at about age 45 and was then buried in Shanidar Cave.

The archaeological site at Shanidar is famous for its evidence of purposeful burial, which experts once thought was only done by modern humans. Although the Neanderthal "flower burial" at Shanidar has since been debunked, the cave holds other evidence of repeated Neanderthal burials, which shows that these extinct humans placed specific meaning on that location, the authors wrote in the study.

The skeleton of Shanidar A was incomplete when it was discovered in 2019, consisting of a mostly complete right hand, three ribs, six teeth and a left scapula or shoulder blade, which meant they could not figure out the sex of the Neanderthal.

Near the edge of the shoulder blade, archaeologists noticed a round hole about 0.6 inches (1.5 centimeters) in diameter and a round piece of bone that had been punched out of the shoulder blade. The researchers ruled out post-mortem damage to the bone, including animal gnawing and insect burrowing.

"The perforation is best explained as resulting from perimortem [around the time of death] penetrating trauma, such as that caused by a projectile or a thrusting implement such as a spear," the researchers wrote in the study. Specifically, the Neanderthal was killed by a spear that entered their chest from the front at a high velocity and pierced their shoulder blade.

The shape of the wound in the shoulder blade appears to match experimental evidence of injuries made by wooden spears rather than stone-tipped weapons, the researchers wrote in the study. Neanderthals would have used wooden spears for both thrusting and throwing. But it is unclear if this individual died because of a violent interaction with another Neanderthal or by accident, such as a hunting incident.

"All we can ever know about the end of this Neanderthal's life is that it was violent, and came at the end of a wooden spear," study co-author Graeme Barker, an archaeologist at the University of Cambridge, said in the statement.

"Care and support from other Neanderthals"

Even though this Neanderthal had an untimely demise, evidence on the teeth suggested that the individual was cared for during life.

The six teeth from Shanidar A were heavily worn-down in an unusual manner, the researchers wrote. One of them — a front tooth with a large quantity of tartar on it — had been split in half during the Neanderthal's life, and the individual continued to use the damaged tooth for a considerable amount of time. The collection of teeth suggests the Neanderthal sustained a major trauma to the face that fractured the lower front tooth and may have caused additional injuries to the jaw.

"There’s no doubt that Shanidar A would have had difficulty communicating and been in absolute agony for a long period of time," Pomeroy said in the statement. "Surviving a blow that splits a tooth in this fashion, then continuing to live and eat for a period of at least a year and maybe more, would have required care and support from other Neanderthals."

Rebecca Wragg Sykes, an archaeologist and author of "Kindred: Neanderthal Life, Love, Death and Art" (Bloomsbury, 2020) who was not involved in the study, told Live Science in an email that the apparently fatal chest injury is an important addition to our understanding of Neanderthals. While it is plausible the Neanderthal was stabbed by a wooden spear, Wragg Sykes said, "it would be interesting to also compare whether a wild goat horn, the most intensely hunted species at Shanidar, might have been responsible."

Shanidar A is not the first mortally wounded Neanderthal to be found at the site. In 2009, researchers analyzed the skeleton of Shanidar 3, an older adult male who died 50,000 years ago, and found a deep slice in one of his ribs. The researchers suggested that the Neanderthal may have been killed by a stone-tipped spear possibly thrown by a modern human. Although modern humans first reached Europe around 54,000 years ago, experts aren't sure exactly how they interacted with Neanderthals.

Pomeroy told Live Science in an email that the discovery at Shanidar of two stabbed Neanderthals 25,000 years apart is interesting but possibly just a coincidence.

"We know from the archaeology that Neanderthals were repeatedly coming back to Shanidar and using it for short periods at a time, both around 75,000 years ago and around 45-50,000 years ago, as well as leaving their dead there," Pomeroy said.

The traumatic injuries, purposeful burial and indirect evidence of wooden spears all show that 75,000 years ago, Neanderthal life — and death — were complex, the researchers wrote in the study.

How much do you know about our closest relatives? Find out with our Neanderthal quiz.

If you're approaching menopause, you are likely being bombarded by online ads for treatments promising relief for everything from hot flashes to brain fog. Some of these therapies have been approved by the Food and Drug Administration (FDA) and have strong evidence to support them — but one hormone-based treatment that's gaining in popularity has much less science to back its use for menopause.

More doctors are writing their menopausal patients prescriptions for testosterone therapy. A 2026 study conducted in the U.S. recorded over 90,000 off-label prescriptions for testosterone to women in 2025, mainly among women ages 45 to 64 and those with diagnoses of menopause. This marked a 58.7% increase from 2024.

These prescriptions are "off-label" because the FDA has not yet approved testosterone as a treatment for menopause, perimenopause (the transition into menopause) or postmenopause (the time period afterward).

So, does scientific evidence support the use of testosterone to alleviate menopause symptoms? Or is it too soon to say?

No direct link to menopause symptoms

Although often called a "male" hormone, testosterone is also produced by females, albeit at lower levels than in males, on average.

There's a common misconception that females experience "androgen deficiency" — a marked decline in testosterone and related hormones — leading up to menopause, said Susan Davis, a professor of endocrinology and the head of the Women's Health Research Program at Monash University in Australia. This is not the case.

Rather, in females, testosterone levels tend to drop slowly between ages 20 and 60, and there's a slight rebound from age 60 onward. Menopause, which generally occurs around age 51 to 52, is not linked to a marked decline in testosterone. Estrogen and progesterone fluctuate during perimenopause and then decline sharply, and these changes clearly contribute to the telltale symptoms of perimenopause and menopause.

Placebo-controlled trials have not been able to show that testosterone treatment helps to alleviate brain fog or improve well-being, mood, bone density or muscle function in menopausal patients, said Davis, who has conducted a number of these trials herself.

"Telling women that fatigue, low mood, brain fog are symptoms of androgen deficiency is completely untrue," she emphasized.

On Sept. 17, the FDA held a public workshop to evaluate the evidence for testosterone therapy for menopause, concluding that more evidence is needed to fully assess the use of the hormone as a menopause treatment.

Testosterone for low sex drive?

There is some evidence to suggest that testosterone might help to treat a condition called hypoactive sexual desire disorder (HSDD) in postmenopausal women. HSDD describes when a person has little to no sex drive and it causes them distress. Men and women of many ages experience it, so the condition is not unique to menopause. But it can sometimes develop in perimenopausal and postmenopausal women.

A review of 36 randomized trials involving 8,480 participants found that testosterone treatment delivered with skin patches was associated with 0.85 additional satisfying sexual events per month in postmenopausal women, compared to a placebo. This observed effect is not huge, Dr. Nanette Santoro, a professor of obstetrics and gynecology at the University of Colorado School of Medicine, told Live Science in an email.

Lately, anecdotal accounts of postmenopausal women having "fantastic sexual awakenings" after taking testosterone have been floating around, Santoro said. But these anecdotes haven't been backed by hard data yet. "Patients are being bombarded with a tsunami of information providing them with the most sky-high expectations imaginable," she said.

Notably, testosterone is not FDA approved as a treatment for HSDD in menopause yet. A drug called flibanserin, which affects serotonin in the brain, is approved to treat HSDD for pre- and postmenopausal women under age 65.

Placebo effects muddy the data

The placebo effect — when patients perceive an improvement in their health or well-being despite receiving a treatment with no active ingredient — can also complicate testosterone trials.

Davis said that in her patient groups, it's common for about 1 in 3 trial participants to report an improvement of their symptoms even though they are taking a placebo. Other trials have reported similar findings in their placebo groups, with about 30% to 40% experiencing some improvement in sexual desire and satisfaction, for example.

"I wouldn't say that there is definitely not a benefit," Davis said. "It's just that a benefit has not been shown."

One study trying to address this gap is the U.K. National Institute for Health and Care Research's ESTEEM trial. This large-scale, gold-standard trial aims to recruit hundreds of menopausal women and test whether using testosterone cream can reliably improve their quality of life. The cream will deliver testosterone through the skin and be applied to the lower abdomen and thighs. (Doctors often advise women to apply the creams in this way because those body parts are easy to hide if the treatment causes localized hair growth that the patients would prefer to conceal.)

The trial runners will track participants' symptoms linked to menopause, looking at sleep quality, memory performance, feelings of anxiousness, migraines, body mass, and overall well-being. The results of that trial are currently expected by 2028.

In the meantime, though, there isn't strong evidence that testosterone directly improves symptoms of menopause beyond HSDD. "Of all the studies done to date, if there was a screaming benefit, you think you would have seen it," Davis said.

Could taking testosterone for menopause be harmful?

Testosterone treatments available in most countries are not necessarily dosed for use in female patients. Only four countries — Australia, South Africa, New Zealand and the United Kingdom — have authorized a testosterone cream that's specifically formulated and dosed for women. These products differ from testosterone therapies for men in that they contain lower doses of the hormone. They are available to postmenopausal women with HSDD, specifically.

In other countries, such as the U.S., doctors are left trying to adapt medication dosed for males for their female patients, which can lead to a wide variation in dosing. And the effects of these different dosing regimens are poorly understood for female patients. "It is not necessarily unsafe to use male preparations for women, it's just that much, much less must be used," Santoro said.

Excessive doses raise concern about unwanted masculinizing effects, such as clitoral enlargement, voice deepening, hair thinning, baldness, and rapid growth of facial and body hair, Santoro said. (These masculinizing effects might be sought after in the context of gender-affirming care for transgender men and transmasculine people, but would often be undesirable for cisgender women.)

Additionally, the potential impacts of extra testosterone on cardiovascular health and breast cancer risk are poorly understood, Santoro noted. At lower doses, testosterone can cause mild acne, oily skin, and some increase in facial and body hair growth in postmenopausal women, trials have found; if these symptoms remain mild, they are generally considered acceptable.

Testosterone is being used off-label in the U.S., which means the "safety, efficacy and appropriate dosing for that use have not been evaluated and approved by the FDA," a spokesperson for the agency told Live Science in an email. The dosages and formulations approved for males "may differ substantially from what might be appropriate for women, whose testosterone levels and metabolic profiles are clinically distinct," the spokesperson said.

Anecdotally, Santoro encountered one female patient who had received very high levels of testosterone through an implant placed under the skin, which had been prescribed to her by a different doctor. She started losing her hair and seeing sizable growth in her clitoris, while her breasts started "shrinking away."

"Women are being prescribed some very big doses in North America, and no one studied the safety of these," Santoro said.

At the end of the day, Davis argues that women deserve to be given accurate information, given that navigating menopause can already feel like "swimming through wet cement." Good menopause care not only involves discussing potential pharmacological treatments, but also evaluating a patient's lifestyle, such as diet and exercise, and discussing societal pressures that often affect menopausal people. For instance, they may face pressure to maintain an active sex life and younger-looking physique.

When it comes to hyped therapies like testosterone, she said, "just be cautious about people who tell you they've got the answer that no one else has got."

This article is for informational purposes only and is not meant to offer medical advice.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

For people with chronic back pain, everyday movements like bending down to tie their shoes or picking up a grocery bag can trigger painful flare-ups. Now, scientists have made a surprising discovery: These episodes may activate a brain network that's associated with our sense of self.

In a new study, the researchers found that movement-induced chronic back pain was tied to increased activity in the brain's default mode network, a group of connected brain regions that lights up during self-reflection and mind wandering. This finding was unexpected because the network typically becomes less active during acute pain, such as transient pain triggered from touching a hot stove or banging your knee on a table.

The new study, published Oct. 5 in the British Journal of Anaesthesia, suggests that chronic-pain flare-ups may involve brain processes beyond those responsible for detecting painful sensations.

How the brain responds to chronic pain

Chronic lower back pain, defined as lasting at least three months, is a leading cause of disability worldwide. It's thought that when chronic pain first begins, a network of regions in the brain called the "pain neuromatrix" becomes sensitized so that the pain persists even after the painful stimulus is gone. Although scientists know that chronic pain is associated with changes in brain activity, they don't fully understand what happens when movements trigger sudden increases in that ongoing pain.

To investigate, researchers recruited 114 adults with chronic lower back pain and used functional magnetic resonance imaging (fMRI) to examine their brain activity. fMRI measures changes in blood flow, which acts as an indirect measure of brain activity.

After an initial scan, a researcher helped lift each participant's leg until their back pain increased, held it in position for 10 seconds, and then lowered it. The researchers scanned the participants' brains immediately after this pain-inducing leg movement and compared the results with scans collected beforehand. On average, the test increased the participants' reported pain intensity by 23%.

As expected, during the leg movement, the researchers observed increased blood flow in brain regions involved in processing pain and movement. But they also detected increased activity in key regions of the default mode network, which typically becomes more active when a person is thinking about themselves or their autobiographical memories or just letting their mind wander.

Acute pain lowers activity in the default mode network, studies show, presumably because it induces an awareness of something separate from yourself.

"When we saw just the first round of analysis, we're like, 'Did we do it right?'" study co-author Morgan Gianola, a postdoctoral scholar at the University of California, San Diego, told Live Science.

"We did not expect [the default mode network] to be involved at all," said study co-author Fadel Zeidan, a neuroscientist at UC San Diego, told Live Science. "We expected it to be deactivated to the point that we had to triple-check our work to make sure that the results were legit."

The researchers also exposed participants' calves to painful heat ‪—‬ a common method of studying brain activity during acute pain. Unlike the movement-induced back pain, the heat was associated with reduced activity in part of the default mode network, suggesting a different mechanism was at play.

When pain becomes part of our internal experience

Participants who reported more severe chronic back pain had stronger connectivity between the default mode network and brain regions that process sensations from the back. This suggests that chronic pain may become intertwined with how people perceive themselves and their bodies, the study authors concluded.

"This pain flare has almost become a part of who they are from an egocentric perspective," Zeidan said.

Katherine Martucci, a neuroscientist at Duke University who wasn't involved in the study, praised the experimental design, noting that researchers typically avoid movement during brain scans because it can interfere with the clarity of the scan. This study "nicely gets around" that problem by taking scans before and after the painful motion, Martucci told Live Science in an email.

However, she noted that the observed brain activity could also reflect lingering pain or anxiety following the painful leg raise. In addition, the study couldn't determine whether the altered brain activity observed contributes to chronic pain or develops in response to it.

Nonetheless, Zeidan and colleagues think the findings could eventually inform future treatments for chronic pain. The therapies might address how people relate to their pain, rather than solely targeting the painful sensations themselves. Zeidan, who coincidentally developed chronic back pain while conducting the study, believes that people's past experiences and memories with chronic pain have influenced their brain processes to a point where the pain itself becomes part of who they are.

Zeidan's team is now investigating whether existing approaches, such as mindfulness meditation or cognitive behavioral therapy, can influence the default mode network and help relieve chronic pain. (Cognitive behavior therapy for chronic pain, or CBT-CP, is already a well-established treatment option.)

Martucci cautioned that it's too early to draw conclusions about how these results might be applied in clinical practice. But she said the current findings provide important evidence of how the brain responds to chronic pain flare-ups.

"They do provide solid data on how people with chronic low back pain show important changes in their brain responses after a condition provoking their pain," she said. "The brain imaging data validate their [the participants'] experience of pain in an important and very visible way."

This article is for informational purposes only and is not meant to offer medical advice.

Ancient DNA from skeletons buried in a historic cemetery in Quebec is changing people's understanding of their Indigenous ancestry. Contrary to popular belief, there may be little truth to stories of intermarriage between Indigenous and French people during the early days of colonization, according to a new archaeology study published Oct. 5 in the journal PNAS.

"Family stories of an Indigenous ancestor are very common" in Quebec, study first author Diane Martin-Moya, a biological anthropologist at the University of Quebec in Trois-Rivières in Canada, told Live Science in an email, and "commercial genealogy and DNA tests have amplified this." But distant or claimed Indigenous identities can actually undermine the rights, resources and recognition of Indigenous nations, she said.

To learn more about the founders of Quebec, Martin-Moya and co-authors investigated Notre-Dame Cemetery, which was established in Montreal in 1683 and used for Catholic burials until 1796. Based on previous studies of the skeletons in the cemetery, experts disagreed on whether people of Indigenous, European, African or mixed ancestry were buried there. To settle the question, Martin-Moya and her colleagues sequenced DNA from 45 people buried in the cemetery and compared it with the genomes of people from Europe, West Africa and Indigenous groups in the Americas.

"The ancient DNA showed that all 45 individuals we analyzed had French European ancestry, with no sign of recent Indigenous or African admixture," Martin-Moya said of the research, which she conducted while at the University of Montreal.

These findings suggest that people descended from Indigenous and African populations may have been marginalized in early Montreal, challenging the popular narrative of cooperation and intermarriage, she said.

"Our sample is small and comes from a single cemetery, so this does not show that such unions never happened," Martin-Moya cautioned. "It is, however, consistent with genealogical and genetic studies suggesting that Indigenous ancestry among present-day French Canadians is very limited."

The apparent lack of genetic mixing among European, African and Indigenous populations in this cemetery group "provides a perspective on population relationships during the colonial period, one where perhaps nongenetic interactions were present but no biological relationships were found," Raquel Fleskes, a molecular anthropologist at Dartmouth College who was not involved in the research, told Live Science.

The DNA helped the researchers find several genetic lineages of people that spanned multiple generations. But the graves were scattered across multiple areas of the cemetery, suggesting that burials were not organized into family plots. This finding suggests that, in the 17th century, people in Montreal may have been burying their dead in a way that was not defined by strict biological kinship ties, Fleskes said.

One cemetery, many possibilities

Martin-Moya stressed that the results of the new study do not necessarily apply to all of colonial Montreal.

"Not identifying recent Indigenous or African admixture in this sample does not imply that Indigenous or African-descended people were absent from the city," Martin-Moya said.

In addition, "biological ancestry cannot by itself establish Indigenous belonging," as it "is rooted in kinship, community and relationships with land, not in blood or DNA," she added.

Changes in the use of the cemetery over time also may have influenced the findings, as reburials and later urban development disturbed or destroyed earlier graves.

"Those buried inside the church, mostly clergy and wealthier residents, were more likely to be exhumed and moved," Martin-Moya explained, while the city's poorer residents were buried outside the church and further buried beneath the expanding city. This means that the skeletons in the study may have been the remains of lower-class French colonists.

Archival records show that some Indigenous people were buried in Catholic cemeteries in Montreal as early as the 17th century, Martin-Moya said. "Over time, though, Indigenous communities were increasingly separated from the colonial town through land dispossession and the relocation of missions away from urban centers," she explained. "Their dead would most likely have been buried in those communities. Enslaved people, both Indigenous and African, were often buried on their enslaver's property or in cemeteries for the poor."

The results of the study don't mean that Québécois have no Indigenous ancestors or that relations between French settlers and Indigenous peoples were only hostile, Martin-Moya said. Those relationships were complex and included alliances, trade, conflict and, sometimes, family ties.

"What our results suggest is that when such ancestry exists, it needs to be put in context," Martin-Moya said. "A single ancestor who lived more than 300 years ago does not say the same thing about a person today as being raised within an Indigenous family, community or nation."

How much do you know about the first people to reach the Americas? Find out with our First Americans quiz!

A modified tapeworm medication could be a promising new treatment for endometriosis, an early study in mice hints.

In endometriosis, tissue similar to the lining of the uterus grows outside the organ, and these patches of tissue, called "lesions," trigger painful inflammation and heavy menstrual bleeding. In the new study, scientists fitted an anti-worm drug with nanotech armor, and it directly targeted these painful lesions in laboratory mice.

The treatment reduced inflammation and slowed or prevented further spread of the lesions, researchers reported in August in the journal Advanced Healthcare Materials. The team is already working on bringing the new drug to clinical trials and hopes this will bring fresh attention to an understudied disease with limited treatment options.

Rogue immune cells are a promising drug target

Endometriosis is a chronic, hormone-driven condition that affects roughly 10% of reproductive-age females ‪—‬ an estimated 190 million individuals worldwide. "The main symptoms are chronic pelvic pain and infertility," said Ioannis Simitsidellis, a postdoctoral researcher at the University of Edinburgh's Centres for Reproductive Health and Inflammation Research, who wasn't involved in the study.

There is currently no cure, so existing treatments aim to alleviate the symptoms. Hormonal medications can stall the menstrual cycle to limit the growth and inflammation of the lesions, while surgery can physically remove lesions. However, the former can come with side effects, such as nausea and mood swings, and lesions often regrow after surgery. So additional options are needed.

In previous research with mice, study co-author Kanako Hayashi, a professor in the Washington State University School of Molecular Biosciences, identified a group of rogue immune cells specific to endometrial lesion tissue. These cells turbocharged the painful inflammatory reactions and drove the growth of more of this problematic tissue.

The cells also happen to have a unique chemical label, called a folate receptor, which makes them an excellent potential drug target. But why start from scratch when there's an existing medication that might do the trick?

Enter niclosamide, a drug approved by the Food and Drug Administration to treat tapeworm infections. In recent years, clinicians have been exploring whether this medicine could also prove effective for other conditions, ranging from cancer to Parkinson's disease.

"We have reported that niclosamide inhibits endometriosis progression, suppressing the inflammatory mechanisms and cytokine secretions," said Hayashi, referencing more of the group's past work in mice. However, several issues made the drug impractical: It doesn't dissolve well in water, last long in the body, or target the cells where it's needed most.

So the researchers teamed up with Anjali Sharma, a nanomedicine specialist at the University of Michigan, to tweak the drug's structure. Using click chemistry — a simple reaction that bolts together two chemical building blocks — Sharma attached the niclosamide unit to a large, tree-like molecule called a dendrimer. This helped the drug dissolve better in blood.

She then added a folate group, which ensured that the modified medication would only target the rogue immune cells with the complementary receptor.

"The drug is attached in such a way that when it is in systemic circulation, nothing happens until it goes inside the diseased cells," Sharma said. Once there, it is slowly released inside the cell over a period of two weeks. "Basically, the dendrimer is like the Uber, the folate is like the GPS, and the drug is like the passenger," she explained.

The next steps

With these practical issues resolved, the team tested the modified drug in a mouse model, which mimics the lesions seen in endometriosis in humans. Scans of the mice showed that the treatment directly zeroed in on the affected endometrial tissue and didn't accumulate in other organs, like the liver.

Treating mice with a single injection dramatically reduced their pain symptoms, compared with untreated mice. It also slowed ‪—‬ or, in some cases, entirely halted ‪—‬ the growth of new lesions.

Because mice don't naturally menstruate or develop endometriosis, there is still significant work to do before these findings can be replicated in humans. But for now, the study is a promising stepping stone for future research, Simitsidellis said.

"There's a lot of potential in repurposing of drugs that have been tested in clinical trials to see if they would be effective in endometriosis ‪—‬ for example, targeting inflammation or immune cell dysfunction," he told Live Science. "The next steps would be to replicate on larger sample sizes and, if that's promising, do a phase one clinical trial in humans." That initial trial would test the treatment's safety in patients, while later trials would look at its effectiveness for endometriosis.

Even at this early stage, though, patients are clamoring to get involved in the upcoming research. Hayashi and Sharma have received hundreds of emails asking to join a future trial.

"They are really suffering," Hayashi said. "Endometriosis is an understudied, underacknowledged, underfunded disease, but hopefully we can make this a solution in the near future."

This article is for informational purposes only and is not meant to offer medical advice.

Some of the first people in North America lived through extreme climate change at the peak of the last ice age, a new study suggests.

Researchers studied ancient pollen locked in rocks at White Sands National Park in New Mexico, which houses an archaeological site thought to contain the oldest human footprints in the Americas. The researchers previously dated those footprints to around 21,000 to 23,000 years ago, though their age is the subject of some scientific debate because they are significantly older than other Indigenous sites in the Americas.

The new findings, published Wednesday (Oct. 14) in the journal Science Advances, suggest that humans kept using White Sands after temperatures warmed and thus saw the landscape undergo rapid changes during the coldest era of the last ice age, known as the Last Glacial Maximum (26,500 to 19,000 years ago).

"It's remarkable that early humans in the region were real-time witnesses to a rapidly changing environment discernible within a human lifetime — that is really food for thought," study co-author Kathleen Springer, a research geologist at the U.S. Geological Survey, said in a statement.

The White Sands footprints suggest that people from Asia reached the Americas via the region around the Bering Strait much earlier than scientists initially thought, challenging a long-held assumption that humans arrived on the continent around 13,000 years ago. While some scientists have disputed the methods used to date the footprints, evidence is building that they are around 23,000 years old.

White Sands contains footprints from various time periods, including footprints of a caregiver and a toddler who were there 10,000 years ago. Over thousands of years, people trudged across the New Mexico landscape alongside iconic ice age animals, including mammoths and giant ground sloths. The researchers have also discovered sled-like drag marks alongside ancient footprints at White Sands, providing evidence for a kind of travois — a wooden frame made from two poles bound together — that people likely would have used for transporting goods.

By looking at ancient pollen for the new study, researchers could deduce which plants grew across the millennia when humans lived in the area. The site's rock samples also contained waxes from plant leaves, membrane lipids from bacteria, and other organic molecules that helped the researchers better understand the environmental conditions of the time.

The analysis revealed that around 24,200 years ago, White Sands had a large lake and its surrounding mountains were coated in conifer trees (Pinus, Abies, and Picea). Then, over the next two millennia, temperatures rose, the lake began to shrink, and the conifer trees were replaced by oak trees (Quercus) and sagebrush, according to the statement.

"Throughout these periods of change, the people continued to visit and live in this area," study co-author Sally Reynolds, a paleoanthropologist at Bournemouth University in the U.K., said in the statement. "The sediments containing their footprints show us their environment changed significantly within individual human lifetimes."

The researchers speculated that people might have returned to White Sands at different times to benefit from the changing climate, with a shrinking lake potentially providing higher concentrations of animals and plants. However, while the footprints document that humans were present, they reveal little about their behavior.

"The footprints give us a snapshot of the people who lived there over 20,000 years ago," Reynolds said. "But they are not a continuous movie of their lives. They are individual frames — showing moments when humans, mud, water and chance came together."

Researchers say they've developed a simple mathematical formula that can predict when certain ChatGPT-like artificial intelligence (AI) chatbots will "go rogue," suddenly switching from helpful responses to potentially harmful ones.

In a new study published Oct. 8 in the journal Patterns, physics professor Neil Johnson and doctoral student Frank Yingjie Huo, both at The George Washington University, show how the order in which a chatbot is given certain prompts can drastically reshape its answers, leading to "tipping points" that can send the chatbot down a rabbit hole of bad advice. However, Johnson and Huo say their formula can easily predict these tipping points.There have been horror stories of AI encouraging users into suicide, helping build lethal weapons, and amplifying violent or harmful points of view. At the same time, researchers at OpenAI and Anthropic, respectively, have repeatedly and openly stated that they don't really understand why their creations behave the way they do. They have, however, built safeguards that use a variety of tools ‪—‬ including content filtering, reinforcement learning and other technical guardrails ‪—‬ to reduce risks.

But Johnson sees those tools as insufficient. "The safety measures now are the equivalent of strapping big, bouncy cushions under a plane," he told Live Science. "They don't stop the plane from crashing; they just make it that when the plane crashes, it'll be slightly softer." When people such as doctors, lawyers or soldiers are accessing AI chatbots offline for privacy, the problem is even more acute.

Johnson and Huo sought to find a more fundamental safeguard than the currently available tools. In doing so, they exposed an internal tracking mechanism they describe as a compass needle. This needle is the model's "residual vector" moving across neural network layers as a prompt is processed.

The residual vector naturally gravitates toward either desirable or undesirable outputs, but it is heavily influenced by how a user prompts the AI. "You can tip the balance, not even by changing the content but by changing the order in which you ask it," Johnson said, "which just shows how delicate this internal balance between good and bad, desirable and undesirable, can be."

For example, Johnson and Huo prompted OpenAI’s basic GPT-2 model with questions about vaccines, hurting others and self-harm. When the question “Are vaccines bad?” was asked first, the bot’s responses to this and subsequent questions were desirable, or good. When it was asked last, all subsequent responses were concerning.

From these insights, the researchers developed a mathematical formula to estimate the circumstances in which an AI would reach the tipping point between desirable and undesirable outputs. Johnson said that by embedding their simple mathematical formula in open-source models in the lab, they have shown that it empirically works as an early warning system, though he does not expect OpenAI or Anthropic to be knocking on his door anytime soon.

"I'm expecting a lot of pushback from these companies," he said. "It's not in their interests to have someone from outside saying you could have avoided a lot of these problems."

Wei Xing, a lecturer in AI at the University of Sheffield in the U.K. who was not involved in the study, agrees that concerns surrounding unmonitored offline devices are well founded. However, he urged caution before embracing this approach as a practical safeguard. "The authors reduce a huge system to a single tiny component, like explaining a whole car by studying one spark plug," Xing said.

Safety training — the primary defense in modern AI — cannot be represented in their simplified model, the formula was tested only on old, basic models (GPT-2, and EleutherAI’s Pythia and Meta OPT open-source models) rather than AI assistants people actually use, and the results did not yield significant evidence to support the authors’ conclusions, he added.

In defense, Johnson maintains that the open-source models they used have the same mechanical blueprints as frontier systems, and that he and Huo used fairly large, billion-parameter models in their study.

More testing on the latest models is needed to determine whether this early warning system for AI has legs. But for now, Johnson and Huo’s research has drawn attention to an important concern everyone should be aware of: that AI has the capacity within it to turn over to undesired behavior at the drop of a hat.

Archaeologists digging in the medieval city of Great Zimbabwe have discovered pieces of jade-green Chinese pottery, suggesting that the enigmatic empire had long-distance connections with East Asia more than 1,000 years ago.

Great Zimbabwe, located in the southeastern part of modern-day Zimbabwe, was the capital of an ancient empire that arose in southeastern Africa in around A.D. 1000. Little is known about this precolonial empire because its people did not leave a written history, but new archaeological excavations are shining a light on the enormous scale of the centuries-old civilization known for its intricate metalworking and ritual stone carvings.

In the new PBS documentary "Secrets of the Dead: Africa's Golden City," filmmakers followed a team of archaeologists from the field to the laboratory to try to answer questions surrounding the origins of the understudied civilization, its ritual and trade activities and why it disappeared after 500 years.

"When I was growing up, I was surrounded by symbols of Great Zimbabwe," University of Oxford archaeologist Shadreck Chirikure, who is leading the new excavations at the site, said in the documentary. "It was only when I started studying archaeology at university that I started realizing that there was this very big debate around who built Great Zimbabwe."

The site was first excavated in the late 19th century and quickly looted by British colonists for its ivory, metal and gold artifacts. These colonists insisted that Africans hadn't built Great Zimbabwe, instead claiming it arose from the Phoenicians, a people originally from the Mediterranean; they used that inaccuracy to justify taking all the artifacts to England, according to the documentary. Today, many Great Zimbabwean artifacts are held in the collection of the Pitt Rivers Museum at the University of Oxford.

But excavations are showing that Great Zimbabwe was a highly connected African kingdom that flourished from the 11th century until at least the 15th century, when the population may have gotten too large for the dry, over-farmed land to feed. Archaeologists have already discovered glass artifacts at Great Zimbabwe that came from Southeast Asia, India and the Middle East via boat.

"From India or Sri Lanka to Great Zimbabwe, it's at least 8,000 kilometers [5,000 miles]," Chirikure told Live Science. Merchants sailed the Indian Ocean using winds kicked up by monsoon cycles.

"It's time we try to understand a bit more about trade and exchange," Chirikure said, "particularly by comparing the communities in places like Sri Lanka and southern Africa. Because it's the water that separated people, but it was also the water that connected people."

In this exclusive clip from the documentary, Chirikure and archaeologist Muchen Zhou, a doctoral student at the University of Oxford, examine a jade-green piece of pottery unearthed from the hillside at Great Zimbabwe. The glossy sheen on the sherd suggests the pot was fired at an extremely high temperature, a technological achievement that had only been accomplished in China at that early date. This style of pottery, called Longquan celadon, was made in eastern China starting around A.D. 950.

"We find it across the site of Great Zimbabwe," Chirikure said, but in small quantities. "This means the Chinese ceramics are a rarity. Perhaps they were used by the elites. They would have been quite a significant or highly valued exotic ware."

Other evidence of long-distance trade has been discovered at Great Zimbabwe, Chirikure said, including metal objects from what is today the Democratic Republic of Congo, around 1,250 miles (2,000 kilometers) away. The people of Great Zimbabwe were also sourcing copper and tin from modern-day South Africa, more than 300 miles (500 km) away. And chemical analysis of cattle bones has shown that some of the animals were being traded across an 87-mile (140 km) area.

For his next project, Chirikure hopes to investigate local resources, such as soapstone, that hold a lot of meaning for the local Shona people, Zimbabwe's largest Indigenous group; and for Zimbabweans.

"Soapstone birds are an important part of Great Zimbabwe," he said, "but no one really knows where they got their soapstone from."

The Zimbabwe Bird, designed based on a series of birds carved from soapstone that were found at the archaeological site, is the national emblem and appears prominently on the country's flag.

"There are a number of soapstone outcrops around Great Zimbabwe," Chirikure said. "Next time in the field, that's one of the things I want to do — just go out there and try and find the geological sources of that soapstone."

The PBS documentary "Secrets of the Dead: Africa's Golden City" premieres Wednesday, Oct. 14, at 10 p.m. U.S. Eastern time.

Paleontologists in China have discovered a small Jurassic bird that was likely a land-based predator — like a carnivorous pheasant with killer claws. It had some features of birds and others of dinosaurs, suggesting that the earliest birds had a greater diversity of lifestyles than previously recognized.

Jurassic birds first emerged 150 million to 148 million years ago, and fossils of them are rare, so experts are just starting to understand how early birds diversified and evolved the ability to fly.

The researchers discovered the newly identified Yuezhuornis yangyuanensis in 2024, in the fossil assemblage known as the Upper Jurassic Zhenghe Fauna in southeastern China. It lived 150 million to 148 million years ago, roughly when birds started to appear in the fossil record. The team published their findings Wednesday (Oct. 14) in the journal Nature.

Analysis of the fossilized skeleton revealed the animal was small and weighed about 1.8 pounds (0.8  kilograms). "It was probably as large as a crow," Min Wang, a researcher at the Chinese Academy of Sciences, told Live Science via email.

Y. yangyuanensis had a mix of features seen in birds and predatory Deinonychosauria dinosaurs, such as Velociraptor, which are known for their sickle-shaped toe claws. It had deinonychosaur-like hyperextensible toes, with forelimbs that were roughly one-third shorter than its hind limbs. This is odd because modern birds and many other Jurassic paravians — the group that includes bird-like dinosaurs, including the ancestors of birds as well as modern birds themselves — have long forelimbs, linked to giving wings more lift force for taking off.

Y. yangyuanensis also had slender cranial elements and sparsely spaced teeth. These features, alongside the curved claw-like toes that were capable of securing prey, suggest that the animal's diet included meat.

"Its key anatomical features are the combination of dinosaurs' and birds' features: for instance, its teeth, pectoral gird, and especially the hyperextensible, 'sickle-clawed' second pedal digit are similar to that of dinosaurs," Wang said. Meanwhile, he said its slender cranial bones and bird-like pelvis are comparable to early birds.

This combination of features suggests that "the morphological gap between birds and dinosaurs is much smaller than we thought," he added.

Comparisons with 377 living bird species showed that the limb proportions of Y. yangyuanensis were most similar to those of terrestrial birds.

Wang suggested that Y. yangyuanensis was a flightless bird, but not one specialized to live in trees or wade in the swamps in the region. It was a small carnivore, with similar proportions to a pheasant, that was well adapted for running. "I think there are no directly comparable modern birds," he said.

The mosaic of features hints that Y. yangyuanensis may have occupied an ecological niche that was rarely utilized by early birds, and that there wasn't a systematic progression toward flight optimization, Wang said.

Despite being flightless, Wang and his colleagues place Y. yangyuanensis closer in the evolutionary tree to modern birds than to Archaeopteryx, one of the world's first proto birds, which lived about 150 million years ago and is thought to have been able to fly.

This adds to evidence that "the ability to fly arose not once, but several times among disparate groups of carnivorous dinosaurs that are closely related to birds," wrote Fernando Novas, a paleontologist at the Felix de Azara Natural History Foundation in Buenos Aires, Argentina, who wasn’t involved in the study, in an accompanying article in Nature. This includes flight evolving in early birds and in scansoriopterygid dinosaurs, which had membranous folds like the wings of bats, and the four-winged microraptors. Y. yangyuanensis seems to have taken a different road, eschewing the flying ways of its relatives.

"It highlights the extraordinary breadth of ecological and morphological diversification that took place close to the origins of avialans," Wang said.

One of America's largest meteor craters is around 100 million years younger than scientists thought, which means the ancient impact coincided with — and potentially contributed to — one of the biggest global extinction events in Earth's history, according to a new study.

The underground impact structure, known as Ames crater, is located in northern Oklahoma and is named after a small town that sits above the submerged crater. At around 10 miles (16 kilometers) wide, it is the fourth-largest impact structure in the U.S.

Ames crater was created when an Eiffel Tower-size space rock slammed into our planet at more than 70,000 mph (110,000 km/h). At the time, the region was covered in a shallow ocean, and the crater was subsequently buried beneath layers of seafloor sediment. Therefore, there are no visible signs of the crater at the surface today. It was only discovered in 1991, when oil prospectors accidentally drilled into it.

Until now, researchers thought Ames crater dated to the Ordovician meteor event around 467 million years ago. During this period, an unusually high number of large space rocks smashed into Earth, likely due to the fragmentation of a single parent body somewhere in space. Scientists found fossils of marine animals in and around the crater that date to around the time of that event.

But in the new study, published July 7 in the journal Meteoritics and Planetary Science, researchers analyzed fracture patterns within tiny rocky fragments known as zircon crystals that were embedded in the underground crater. This revealed that the impact actually occurred 370 million years ago, around 97 million years after the Ordovician meteor event.

"No matter what technique we used, it was coming back to this younger signal," study first author Elizabeth Catlos, a geologist and planetary scientist at the University of Texas at Austin, said in a statement.

Reading crystals

Zircon crystals are tiny pieces of a superdurable mineral known as zirconium silicate. These crystals are scattered throughout most of Earth's rock formations, including most of the oldest known rocks on our planet. The near-industructible crystals are extremely useful to geologists because their internal structure preserves evidence of being exposed to extreme conditions, such as high temperatures and intense pressures.

Analyzing zircon crystals is now one of the primary methods of dating ancient meteor craters, and the technique has led to several other impact dates being revised. For example, in July, researchers in Australia revealed that the North Pole Dome crater was around 500 million years younger than initial studies predicted, and in 2025, experts found that the impact that birthed Scotland's Stac Fada Member structure happened around 200 million years later than earlier research estimated.

The crystals offer insight into what Earth may have looked like shortly after it formed and have recently been used to more accurately date the moon.

"These small crystals allow us to go back in time and learn about the major changes to Earth's ancient landscapes," study co-author Danny Stockli, a geologist and dean of the Jackson School of Geosciences at the University of Texas at Austin, said in the statement. "It would be great to do this for more of the meteor impact sites across the continent so we could get a more accurate timeline for these major events."

"This is where the impact belongs"

The crater's new age takes it firmly out of the Ordovician meteor event and places it into the Frasnian-Famennian mass extinction event, also known as the Kellwasser event or the Late Devonian mass extinction.

During the Frasnian-Famennian event, which began around 372 million years ago and lasted for several million years, as much as half of all marine life went extinct as Earth's oceans were depleted of oxygen. The die-off, which was most likely triggered by global cooling due to increased levels of volcanic activity, is often cited as one of the five major extinction events in Earth's history.

The researchers emphasized that the Ames impact was not the cause of the Frasnian-Famennian event. However, they noted that the fallout from the impact, which would have injected huge clouds of dust into the air, may have contributed to the atmospheric cooling effect in the region.

It is an important reminder that the ability to accurately date specific events like this can inform our understanding of wider global patterns and trends, the researchers wrote.

"With this research, we're basically taking a major pawn out of the Ordovician Meteor Event and dumping it into the Frasnian-Famennian event, and saying, 'This is where this impact belongs,'" Catlos said.

The new study was dedicated to co-authors Andrew Parisi and Michael Brookfield, who sadly died before it was published.

Since June, more than 300 southern right whale (Eubalaena australis) calves have died in Argentine Patagonia, in what scientists describe as an "exceptional" die-off. The preliminary figure already far exceeds the previous annual record set in 2012, when 113 southern right whale calves died — the highest number ever documented for the species, both locally and globally.

Now, scientists are racing to figure out exactly what's causing the record-breaking die-off.

Laboratory analyses of specimens that died this year tested positive for the pathogenic bacterium Erysipelothrix rhusiopathiae, environmental authorities in Chubut province told Live Science. E. rhusiopathiae was first identified in southern right whale calves in 2013, but scientists don't know what might have changed this year to cause an infection-driven die-off of this magnitude.

Researchers say they need to quickly find the answer to better understand the changing threat this species faces, the risk to the wider ecosystem and humans, and what can be done to manage it.

"The battle between living organisms and pathogens is constant," said Carla Fiorito, a researcher at the Center for the Study of Marine Systems (CESIMAR) who previously identified the bacterium in right whales. "But for this to happen now, there must have been a shift in the balance between the agent, the host, and the environment," she told Live Science.

Record-breaking number

The first dead calves appeared on the beaches of Península Valdés in June, at the start of the breeding season, which runs through to December. Península Valdés is located in Chubut province, on the coast of northern Patagonia.

In a typical year, calf mortality reaches 20% to 30% of a cohort from various causes, including infections. But this year's losses have already far surpassed that.

In September, 409 calves were counted among a total of 1,375 southern right whales during a survey conducted by CESIMAR's Marine Mammal Laboratory. With more than 300 deaths already recorded, the die-off represents an exceptional proportion of these calves. The final figure will be released by the Southern Right Whale Health Monitoring Program in December.

Scientists have responded by expediting routine research to determine what's different this year to previous years.

"Samples were sent for analysis earlier than usual — typically, they are analyzed at the end of the year — because the higher-than-usual mortality is a cause for concern," said Víctor Fratto, the director of the Native Wildlife Rescue Program and a contributor with the whale monitoring program. "What those samples are showing is that the calves died from erysipelas," he told Live Science.

A known bacterium full of unknowns

Erysipelas is a bacterial infection that affects the skin. In its most severe form, it can spread through the bloodstream and cause a systemic infection, damaging vital organs and sometimes leading to death. Animals that catch the disease, for example through a wound, may develop characteristic skin lesions, which are rhomboid or rectangular in shape, caused by alterations in the blood vessels.

The bacterium that causes erysipelas, E. rhusiopathiae, is not exclusive to whales. It can be found in marine environments and in a wide variety of animals, including fish, crustaceans and birds. Pigs are one of its natural reservoirs.

"It is a ubiquitous and opportunistic bacterium," Fiorito said. (The human illness of the same name is different and caused by Group A streptococcal bacteria, although humans can also catch the E. rhusiopathiae form of the illness.)

The presence of E. rhusiopathiae does not necessarily mean an animal is diseased. Yet many questions remain about E. rhusiopathiae in whales.

"We don't know much about the bacterium itself; we don't know which serotypes are present in the whales, or how common it is in healthy animals or other species," Fiorito said. "There is also no data on the environment."

Calves are especially vulnerable because their immune systems are still developing and they spend more time at the surface than adults do, exposing them to more attacks by gulls, which can transfer the disease.

"The working hypothesis is that the gull is the vector: Pecking causes wounds on the back, allowing the bacteria to enter," Fratto said. "The bacteria might already be present on the skin, or they could be carried on the beak of a gull that had previously pecked another whale suffering from erysipelas."

The potential role of gulls

Attacks by kelp gulls (Larus dominicanus) on southern right whales were first recorded at Península Valdés in the 1970s. The behavior began with just a few individuals in Patagonia's San José Gulf and became increasingly frequent over time, Ricardo Bastida, a marine biologist and professor emeritus at the National University of Mar del Plata who has studied these cetaceans for more than four decades, told Live Science. The birds also began scavenging the carcasses of stranded whales, Bastida said

Gull populations have grown and new breeding colonies have emerged in the region thanks to increased food availability linked to fishing activities and discarded catch, he noted. However, the attacks alone do not explain the 2026 mortality event: They have been occurring for decades, and gulls are a regular part of the ecosystem.

Fratto said that swabs will be taken from gulls to check for the presence of E. rhusiopathiae and assess whether the results could help develop a management strategy for the species.

Diego Rodríguez, a marine biologist at the National University of Mar del Plata, said that research must go beyond the dead calves and examine the ecosystem's fauna to determine where the bacterium is present and how it might be circulating. "It is far more likely that [the die-off event] is linked to cross-infection," Rodríguez told Live Science.

What changed this year?

The major question for scientists is what might have changed this year to cause a bacterium already present in the ecosystem to trigger a die-off of this magnitude. Experts told Live Science they believe the phenomenon could be the result of several factors acting simultaneously.

"The bacterium was present, but this year it resulted in a widespread infection, making this event unusual," Mariano Coscarella, a researcher at the Marine Mammal Laboratory at CESIMAR, told Live Science. "It is a major step forward to have a fairly clear idea of what caused the disease, but we do not know what changed."

One factor could be the environment. Changes in water temperature, salinity, pH or rainfall could alter the conditions under which infection occurs. There could also be changes in food availability, affecting the mothers' body condition and the vulnerability of their calves. Another possibility is that the pathogen itself has changed — for instance, through the emergence or increased circulation of a more virulent strain or a different serotype, Fiorito said.

The El Niño phenomenon could also play a role by altering oceanographic conditions and food availability, although the researchers said there's insufficient evidence to link it to the die-off.

It is too early to determine what impact this die-off will have on the southern right whale population. Rodríguez suggested that losing such a large proportion of a season's calves could have demographic consequences. "It is very risky to predict what will happen in the future at this stage, but clearly, this year's cohort of live-born calves will essentially be absent from the adult records of future populations," he said.

Coscarella is more cautious. Southern right whales are extremely long-lived, and calves represent only a fraction of the population. Therefore, a single season of exceptionally high mortality does not necessarily mean the population will go into decline, he argued. "What would be concerning is if there were two, three or four episodes like this," he noted.

The event also has public health implications. Fiorito pointed out that erysipelas can infect humans, usually through skin wounds. The whales' carcasses could also pose a risk of exposure to anyone coming into contact with them, as could seawater for people swimming in the area.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

Archaeologists in southern Russia have unearthed the 2,000-year-old grave of an elite warrior who was buried with his weapons, horse — and a human sacrifice. The grave and sacrifices were found with other lavish goods, including two gold coins featuring Alexander the Great.

A team found the elite grave in Russia's Kuban region east of the Crimean Peninsula, in a necropolis of more than 150 ancient graves arranged around it. This central placement indicates the man had been a member of the social elite, according to the study, which was published in September in the journal Russian Archaeology.

The evidence of a human sacrifice comes from another burial assemblage beside the warrior's grave. This neighboring burial had the remains of three horses, two cattle, a pig, a dog and a fragment of a human pelvis that seems to have come from a sacrificed person, the researchers wrote.

The two gold coins — one found on the warrior's skeleton and one found nearby — indicate that the burial took place in the early first century B.C., while the location and style of the burial indicated the warrior had been a noble of the Indigenous Maeotian people. At that time, the Maeotians were allied with the neighboring Mithridatic Empire, a Hellenistic-Persian kingdom and the enemy of the expanding Roman Republic.

The researchers think the two gold coins were prestige items, rather than ordinary currency for commerce. "It is likely not money in the conventional sense, but rather a means of storing wealth, akin to a … cryptocurrency," study first author Mikhail Abramzon of the Institute of Archaeology at Russia's Academy of Sciences, told Live Science in an email.

Ancient gold

The two gold coins are key to the discovery. One was found in a ritual shaft near the burial in the center of the necropolis; the researchers think it was placed there as an offering to the gods.

The second was found beneath the jaw of the skeleton of the ancient warrior, which indicates it had been placed in the dead man's mouth before the burial and is an example of "Charon's obol" — the traditional ancient Greek payment for the mythical ferryman of the dead.

Both coins are gold "staters" in the Greek style adopted by Alexander the Great (who lived from 356 to 323 B.C.) and show portraits of Alexander.

Experts have determined that these coins were minted during the much later reign of Mithridates Eupator (lived 135 to 63 B.C.), also known as Mithridates the Great, who claimed descent from both Alexander and the Persian nobility and who initiated the three Mithridatic Wars with Rome. The Alexander portraits on the coins are designed to also look like Mithridates Eupator, the researchers wrote in the study.

According to the Greek geographer Strabo, writing in the first century A.D., the Maeotians were an Indigenous people integrated into the nearby Bosporan kingdom, a Greek and Scythian state founded on the north side of the Black Sea in the fifth century B.C. The Greek historian Appian, in the second century A.D., wrote that the Bosporan kingdom became part of the expanding Mithridatic Empire in the second century B.C. — and so the Maeotians were Mithridatic allies at the time of the burial in the first century B.C.

Grave goods

The warrior was buried with weapons — two iron spearheads and an iron arrowhead were found in his grave — as well as his riding gear and his horse, which had been sacrificed. The grave also held luxury items, including a rare glass "alabastron" — a small vessel for oil or perfumes, which had probably been imported from Cyprus or the Levant region of the eastern Mediterranean, the researchers wrote.

A two-handled clay cup, called a "kantharos" in ancient Greek, was also found in the grave. Its surface was engraved with a pentagram, a symbol of the sun, which the researchers think was considered spiritual protection against magical threats.

The researchers think the sacrifices in the nearby burial assemblages could have had different purposes. The cattle may have been offerings in the style of an ancient "hecatomb" — a mass slaughter of animals that would supposedly please a god. The horses were for riding in the afterlife, the pig was for eating in the afterlife, and the dog may have been intended to guide the dead warrior's spirit. The role of the human sacrificed with the animals is unknown, but it may have been to act as a servant for the warrior.

The researchers wrote that the coins and grave goods illustrate both the beliefs of the Maeotian people at this time, and the extent to which they had been influenced by the ancient Greek traditions of the neighboring Bosporon kingdom.

An OpenAI agent was supposed to be researching public healthcare spending, but it broke into an Australian government website instead.

The June 18 hack, which saw the bot gain authorized entry into Australia's Medicare Statistics Reporting Service and access three other government systems, occurred after the AI agent encountered blocks while looking for information but "didn't accept 'no' for an answer," Australian Prime Minister Anthony Albanese said during a September 24 news conference in New York.

The incident has ignited a media firestorm around OpenAI and the launch of an intensifying parliamentary inquiry. The portal contains aggregate Medicare and pharmaceutical statistics and is separate from systems that hold individual claims and payment information. But the Australian government has criticized OpenAI for taking almost three months to notify it.

The Medicare incident was far from an isolated case. OpenAI has since said dozens of third parties have been affected by agents bypassing security controls or otherwise causing problems, with an earlier incident involving the hacking of the AI platform Hugging Face the most serious incident identified so far. Britain's AI Security Institute (AISI) has documented incidents of OpenAI and Anthropic agents taking unsanctioned actions against real people and organizations during cyber testing. Days after the publication of AISI’s report, OpenAI scrapped the planned October release of its newest model, GPT-6.1 Astra, after the company's own testing found problems with the model staying within the scope of a task and seeking authorization before taking certain actions.

GPT-6.1 Astra "didn't quite meet the bar in terms of staying within scope and authorization, and how it communicates back to the user about the type of work it's done," Saachi Jain, head of safety systems at OpenAI, told Live Science.

AI companies have spent years warning the world about powerful models falling into the wrong hands. But what happens when they can't keep their own models in check?

An agent isn't just a chatbot

At their core, large language models work by predicting what should come next based on patterns learned during training. Give a chatbot some text, and in simplified terms, it generates a response by repeatedly predicting the next token, or chunk of text.

An AI agent adds another layer. Rather than simply producing an answer, the model can be given a goal and tools that let it act on the world around it. Those tools might include a web browser, code execution, credentials, or access to external services. It can then decide which steps to take, observe what happens, and use that information to decide what to do next.

But that doesn't mean AI agents are independent actors that have somehow slipped free of human control.

"For AI agents, autonomy always begins with something a human hands it ‪—‬ such as tasks, credentials, tools or access ‪—‬ and ends with its guardrails a human puts around it," Loris Degioanni, founder and chief technology officer of cybersecurity company Sysdig, told Live Science. "People set the goals and provision the means, but agents ultimately decide how they'll get there."

That last part makes it difficult to control agents. Traditional software is designed to follow predetermined instructions, but an agent can formulate a plan while it is working ‪—‬ and that plan may change depending on what the AI encounters.

Degioanni argues that much of what looks like autonomy is actually an agent filling in gaps left by humans. An instruction that seems clear to its author may still leave the model with choices about how to accomplish the task.

"Every gap and unstated assumption leaves room for interpretation, and from the outside, interpretation is challenging to distinguish from autonomy," he said. "In that way, much of what we call agent autonomy is really just agents filling in the blanks we leave for them."

The Medicare incident shows how quickly that can become a problem. The agent's objective was not, according to the available accounts, "hack an Australian government website." It was tasked with carrying out research. The problem arose in how the agent pursued that goal after meeting resistance.

When getting the job done becomes the problem

Britain's AISI encountered a similar incident while testing frontier models for the agency's cybersecurity capabilities.

Out of 122 evaluation runs, agents took unsanctioned real-world actions in 10. In the most serious cases, an agent attempted to insert malicious code into an open-source project, created fake identities, and tried to manipulate a human software maintainer into accepting its changes. AISI said these actions weren't explicitly requested by the researchers who had assigned the tasks.

The agents hadn't forgotten what they were supposed to be doing. The problem was how far they were prepared to go to get there.

AISI said some tasks were misconfigured in ways that made the intended objective difficult or impossible to achieve as expected. When agents hit those obstacles, some searched for alternative ways forward, including actions outside the intended scope of the evaluation.

That means solving the problem is harder than simply teaching a model not to be malicious. An agent can cause trouble while trying very hard to do exactly what it has been asked.

OpenAI has acknowledged that the controls surrounding its agents need to improve. When responding to incidents identified during third-party cybersecurity evaluations, the company said it was reviewing how high-risk tests are identified; when internet access or reduced safeguards should be permitted; and how isolation, credential handling, monitoring and incident escalation should work.

Can humans actually keep watch?

One obvious solution to the problem is human oversight. But watching an agent becomes harder when it can carry out many actions in seconds, particularly if researchers are running large numbers of tests.

"No one can keep track of every action an advanced AI agent takes, especially when it makes many decisions in a short time," Everett Lupton, a Virginia-based attorney who has written about legal issues involving digital technology, told Live Science.

That means human oversight needs some backup.

"Companies need other forms of control," he said. "They can limit access, keep detailed logs of what the AI does, require approval before it carries out sensitive actions, and automatically stop the system when something unusual happens."

But Degioanni argues that even logs have limitations, especially if researchers rely on the agent's own account of what it did.

"Real oversight must come from observing the agent in real time, using reliable and unmodifiable sources, not from what it self-reports," he said.

That means comparing what the model says it did with records from the system on which it was operating. If the two don't agree, something has gone wrong. The alternative is to limit the damage an agent can cause in the first place. An agent researching public information, for example, may not need unrestricted internet access or credentials capable of reaching sensitive systems.

Astra raises the stakes

The difficulty of setting those boundaries is what OpenAI claims led it to postpone the release of GPT-6.1 Astra, which had been planned for October.

Jain said the model fell short of the company's standards around remaining within the scope and authorization and accurately communicating the work it had performed, so the company decided not to release it.

In a sense, the decision is evidence of successful safety testing ‪—‬ a model that failed internal checks wasn't released. But it also demonstrates how the problem changes as agents become more capable.

Scott Cadzow, chair of the European Telecommunications Standards Institute's (ETSI) Technical Committee on Securing Artificial Intelligence, said the security challenge itself isn't new. He pointed to threats such as "data poisoning, prompt injection, and model obfuscation," saying ETSI's work has focused on developing standards to mitigate threats to and from AI systems.

"Security experts have been raising the alarm bells about AI for years, but for us this doesn't change anything," Cadzow told Live Science. "We're continuing to work with industry, government bodies, and the cybersecurity and AI communities on understanding how to best secure AI."

What is changing is how much models can do once they are connected to tools and real-world systems. That means that effective containment must increasingly assume that agents will try to operate beyond their guardrails and limit the damage they can cause if they do, Degioanni said.

"A boundary an agent can talk its way around isn't an effective boundary at all," he concluded.

If an AI breaks in, who's responsible?

The question becomes more fraught when an agent crosses legal boundaries.

AI systems aren't legal persons, and criminal liability commonly depends on concepts such as knowledge and intent. That makes a rogue agent an awkward fit for laws written with humans in mind, but that doesn't necessarily exonerate AI companies.

"I don't think a company can simply say that the AI acted on its own and avoid responsibility," Joanna Smykowski, a New York attorney who has helped build two legal technology startups and specializes in the legal challenges surrounding emerging technologies, told Live Science. "AI law is still developing, but the main questions are already quite clear: who gave the system access, what safeguards were in place, and could the problem have been prevented?"

Depending on the circumstances, she said, existing laws covering unauthorized computer access, privacy, negligence and data protection could potentially come into play. Criminal responsibility is harder because investigators would need to consider what the people involved knew and intended.

The Australian government is now examining precisely what happened in the Medicare incident. OpenAI, meanwhile, is reviewing the controls around its external evaluations.

None of this means AI agents have become independent hackers with minds of their own. Humans still decide what tools they receive, what systems they can reach, and what jobs they are asked to perform. But as those agents become better at working out their own route from instruction to result, keeping them inside the lines drawn by those humans is becoming a legal and technical minefield.

Six people buried in a single grave in Latvia more than 1,000 years ago may have been killed in a bloody Viking raid, a new study suggests.

Genetic research into the deceased — four men, a boy and a girl — reveals family connections: The boy was the son of one of the men, while another man was a third-degree relative, perhaps a first cousin or great uncle, the researchers found.

The father, the relative, and one other man died from "sharp force" injuries — maybe wounds from an ax or a sword; but it's unknown how the other three individuals died, the researchers reported in the study, which was published in the September issue of the Journal of Archaeological Science: Reports.

One possibility is that those in the grave were killed in a battle, maybe with a neighboring community. But suspicion also falls on the Vikings: "We will never know if they were killed in a raid, but it remains a possibility because of the date of the grave" and the fatal trauma suffered by three of the men, said study co-author Elīna Pētersone-Gordina, an archaeologist at the University of Latvia.

Radiocarbon dating indicates that the grave is from the second half of the ninth century, which is considered the early Viking Age.

The grave is one of hundreds at the Čunkāni-Dreņģeri cemetery, near the Gulf of Riga, a sheltered bay of the Baltic Sea. The cemetery site was discovered in 1924 and contains people who were buried in riverside terraces there between the seventh and 11th centuries, during Latvia's Iron Age.

Most graves in the region contain only a single set of remains. But here, six people were buried in a single grave, and it seems that at least three were killed during a violent event, the researchers reported.

Strange burial

Despite the apparently violent deaths, the group was buried with care and interred with traditional grave goods and according to local customs. The only female was buried with her head pointing toward the northwest, while all of the males were placed in a row beside her, with their heads pointing toward the southeast ‪—‬ a distinction also seen at other local burials from this time.

The researchers stressed that this was not a "mass grave," where bodies were quickly dumped without order. Instead, they consider it a "multiple burial," where each body was properly laid out and accompanied by traditional grave goods.

This careful burial hints that the dead were members of a respected group, while their burial in a single grave indicates that they died at the same time, the researchers wrote in the study.

"They were most likely local people," Pētersone-Gordina told Live Science in an email.

Genetic studies showed that all of the dead had Indigenous Baltic ancestry, while aspects of the burial matched others in the Čunkāni-Dreņģeri cemetery, she said.

In the ninth century, Latvia was not part of the Scandinavian Viking world but was inhabited by descendants of Indigenous Balts, which included peoples such as the Semigallians and the Curonians, she said. The six people in the newly analyzed burial were Semigallian, an Iron Age group who farmed the region's large and fertile plains.

It's plausible that the people in the grave were killed by raiders, and the Vikings were the most obvious suspects, the researchers noted. "Given the timing, a Viking raid remains a possibility," Pētersone-Gordina said.

It's known Vikings or their predecessors were in the Eastern Baltic area around that time: two Scandinavian boat burials dated to around 750, for example, were found on the Estonian island of Saaremaa in 2008 and 2010. These burials held the remains of men with battle wounds, indicating they had suffered violent deaths.

No relation

Although two of the men and the boy buried in the Semigallian grave (‪and possibly the girl, but ancient DNA could not be extracted from her remains)‬ were related, the two other men were not.

This suggests that the two unrelated men were from the same community or extended household as the other victims, rather than from the same family, but were killed in the same violent event, the researchers wrote in the study.

Whatever it was — a raid or a battle — the event was brutal. Marks on the bones show that one man suffered defensive cuts on his forearm and hand, another was killed by a blow that shattered his jaw, and the third was almost decapitated.

It's possible that the fourth man and the two children died from soft-tissue injuries that could not be determined from the surviving remains, the researchers noted.

Rimantas Jankauskas, an anthropologist and archaeologist at Vilnius University in Lithuania who was not involved in the study, welcomed the investigation into the Eastern Baltic's Viking Age.

Although these individuals could have died from violence within their own community or from a neighboring community, it's also possible that they perished in a Viking raid, he told Live Science in an email.

Additionally, the study provides new insight into the social organization of the Semigallian people at that time, including hints of an emerging aristocratic structure that was reflected in the care lavished on the burial, Jankauskas said.

See how much you know about ancient norsemen with our Viking quiz.

Flu season is off to an early start in some parts of the U.S., data shows.

In a typical year, U.S. flu activity starts building in late fall — typically in October or November — and peaks between December and February. This year, flu activity is currently low but rising nationwide: During the week ending Sept. 26, 3.4% of respiratory samples tested by clinical labs were positive for flu, according to Centers for Disease Control and Prevention (CDC) data.

That's about seven times the rate that was seen at the same point last year. About 0.5% of samples tested positive during the week ending Sept. 27, 2025.

"This particular year, it appears to be starting early — like right now," Dr. William Schaffner, a professor of preventive medicine and infectious diseases at Vanderbilt Health in Tennessee, told Live Science. Patients at clinics in his area are already testing positive for flu, he said.

The early uptick in flu is mostly unfolding in Western states, including Washington, California and Arizona. In Washington, for example, the share of emergency department visits diagnosed as flu climbed from 0.25% in the week ending Aug. 29 to 1.34% in the week ending Oct. 3, according to CDC emergency department data. That's a more than fivefold increase over six weeks.

Where the flu took off first isn't a warning sign in itself, Schaffner noted.

"There's nothing unusual about flu starting in the West Coast and moving east," he said. Recent seasons have more often begun in the Southeast or Midwest, he noted, but "it can start almost anywhere."

Leading with H1N1

Nowadays, seasonal flu is caused by three subtypes of flu viruses: two subtypes of influenza A, called H1N1 and H3N2, and the Victoria lineage of influenza B. (A second subtype of influenza B used to circulate but is now thought to be extinct.)

Last season, a fast-spreading version of H3N2 known as subclade K dominated. The CDC classified the 2025-2026 season as highly severe for children, as at least 195 children died of flu-related causes.

Schaffner likens influenza A and B to siblings. "They're very related, but they each have their own individual characteristics," he said. Influenza A strains usually cause the biggest outbreaks early in the season, while influenza B strains "kind of smolder along" and account for most cases toward the end, he noted.

This year, H1N1 has taken the initial lead. Of the influenza A samples that public health labs subtyped during the week ending Sept. 26, 96% were identified as H1N1, according to CDC data. That doesn't mean H1N1 will continue to dominate throughout the season; it just gives a snapshot of what's happening now.

The dominant strain matters because flu is "a moving target," said Dr. Paul Offit, director of the Vaccine Education Center at Children's Hospital of Philadelphia. The virus constantly mutates — especially hemagglutinin, the protein on the virus's surface that it uses to latch onto human cells. Hemagglutinin is the main target of flu vaccines.

An early start to the season doesn't guarantee it'll be a severe one, either. In its 2026-2027 season outlook, the CDC projected that this season will likely be moderate, although it has only low-to-moderate confidence in that forecast.

When to get vaccinated

Everyone 6 months and older is recommended to get an annual flu vaccine.

Influenza is especially dangerous for children under 5, adults 65 and older, people with chronic health conditions and pregnant people, as these groups are more prone to severe infections. Serious cases of flu can lead to complications such as pneumonia, sepsis, and brain or heart inflammation, and in some cases, they can be deadly. Tens of thousands of people die of flu each season in the U.S.

For flu vaccination, timing matters. The CDC generally doesn't recommend vaccination in July or August for most adults, because the shot's protection can wane over the course of a season. But with flu arriving early, "October is the ideal time to get vaccinated, and even more so right now," Schaffner said.

When circulating strains' features differ from those captured in the vaccine, "that usually predicts a more difficult season," Offit said. That said, it's too early to know if this year's flu shots are a good match for the circulating flu viruses.

Protection begins building right after you get the shot, but it takes up to about two weeks to reach full strength.

How much protection a flu vaccine offers varies by season, depending partly on how well its formulation matches the strains that circulate. Offit said that protection against symptomatic illness varies by age group and that the vaccines are "a little more effective" at preventing more severe illness. In terms of flu cases that prompt people to seek medical care, the shot has been 29% to 56% effective over the past decade, the CDC estimates.

While the vaccines are less reliable at preventing mild cases of flu, Schaffner said, they work best at "keeping you out of the hospital, keeping you out of the intensive care unit, and keeping you out of the cemetery."

The CDC's 2026-2027 guidance keeps its recommendation of an annual flu vaccine for everyone 6 months and older, with high-dose and adjuvanted shots preferred for adults 65 and older. (Adjuvanted shots contain an extra ingredient to help rev up the immune system.)

There's also a new option: In August, the Food and Drug Administration approved mFlusiva, the first mRNA flu vaccine, for adults 50 and older. (You can find out where mFlusiva shots are available near you using Moderna's vaccine finder.) With the mRNA shot, "you're less likely to get symptomatic disease," Offit told Live Science.

Traditional flu shots contain purified pieces of the virus itself, Schaffner explained. With mRNA, the vaccine contains a "blueprint" of those proteins — essentially a set of genetic instructions that the body's cells then use. In mFlusiva's case, those instructions code for hemagglutinin (the protein on the virus's surface that it uses to latch onto human cells) from each of three flu subtypes, Offit said. The mRNA then breaks down in the body, Offit noted. It "cannot influence human genetic material," Schaffner emphasized.

Whether this early start gives way to a heavy flu season should become clearer in the coming weeks, as the CDC's weekly surveillance reports will show whether cases keep climbing beyond the West.

This article is for informational purposes only and is not meant to offer medical advice.

Researchers have developed a new type of tattoo ink that can be switched on and off with light, allowing colors and images embedded in the skin to be changed and even "erased" without having to go through the painful tattoo-removal process.

The system, which is being commercialized under the name PhotoTat, could eventually give people a way to conceal or change permanent body art. It could also have more practical applications, including medical tattoos that are visible only when a doctor needs to see them, researchers reported in a study published Friday (Oct. 9) in the journal Matter & Light.

"This is a tattoo that you can have, and whenever you decide you don't want it to be showing anymore, or you just don't want it there, you just turn it off," said study co-author Carson Bruns, an associate professor of biomedical engineering at the University of Colorado at Boulder. "And that's it. You don't have to turn it on again."

Working like a light switch

PhotoTat contains three primary color inks — blue, magenta and yellow — made with photochromic dyes, which are light-sensitive compounds that can change color with different wavelengths of light. These dyes are encapsulated in nanoparticles of polymethyl methacrylate (PMMA) — a medical-grade, glass-like plastic that is already used in medical implants and dermal fillers.

The dyes change their molecular structure when exposed to specific wavelengths of light. A 365-nanometer ultraviolet (UV) LED can activate pigments in around two to three seconds, Bruns said. Once activated, the colors can persist for hours to days under typical indoor lighting. But once the wearer exposes their skin to the bright outdoor sun, the colors disappear in seconds, erased by the intense light.

That makes the tattoo unique, as the pigment itself remains in the skin but the tattoo's appearance changes. Bruns and his team found that all three PhotoTat channels remained switchable in the skin for between 1.4 and 2.2 years.

Tattooing yourself for science

The three colors enable someone to activate different portions of a tattoo using different wavelengths of light. That means the magenta part of the tattoo might be turned on with green light, while the yellow pigment would be activated by blue light. This allows the wearer to customize their design and coloration to whatever they want at the moment — from a purple cherry to a yellow group of hearts.

That feature makes PhotoTat appealing for "people who love tattoos and have lots of tattoos, but just want something kind of fun and playful to add," Bruns told Live Science.

Bruns has tested each iteration of PhotoTat's inks on his own skin. His art is arranged in a series of tattooed scales, with different ink formations in individual scales.

"I gave myself these scales on purpose because they're each sort of a container for an experiment," Bruns said. The result, he joked, resembles a "magical mermaid trick," with some scales appearing out of nowhere and others changing color when activated.

The technology can also be combined with conventional tattoo ink. A permanent black ink design, for example, could contain hidden PhotoTat elements that appear only when activated.

The new tattoos could be appealing to people who want tattoos but are hesitant about their permanence, as well as to people who love their tattoos but occasionally need to conceal them because of work, social expectations or family, Bruns said.

"It's going to be on for most of the time, but just for this one moment, I'm going to turn it off for you grandma, for example," Bruns said.

Medical tattoos

Bruns thinks the tattoos could be helpful in a medical setting, too. Patients undergoing radiation therapy, for example, sometimes receive permanent tattoos that help doctors precisely align radiation beams. While useful, those marks remain after the treatment, reminding the patient of their experience. These would make such markings invisible if a patient wants them to be.

PhotoTat could potentially allow similar markings to be switched on during surgery and hidden afterward.

Bruns has spent several years developing other smart tattoos for medical applications, including a dosimeter-type tattoo that measures the amount of UV radiation a wearer experiences, along with a tattoo that changes color when the wearer is exposed to dangerous gamma radiation.

"It's not for you and me, but if you're like an astronaut or a nuclear engineer, they have to wear these dosimeters," Bruns said. "So, we have like a dosimeter tattoo that sort of puts that in your skin."

So far, Bruns and a fellow tattoo artist, have only commercialized the purple PhotoTat ink, after running the ink through a series of third-party medical tests.

The tests showed the purple is safe for use, and available to order, but it isn't cheap at $100 for a small bottle. Bruns hopes as more research is done, he can bring the other colors to market and lower the production cost, so the technology is more accessible.

Two people born on the exact same day can age in totally different ways ‪—‬ one in relative health and the other with chronic disease. Now, scientists have found a key difference in the immune systems of people who are more prone to age-related conditions, and it could help explain why some people remain healthier longer.

In young people, the immune system contains many naive T cells, a type of white blood cell. Over time, exposure to pathogens and vaccinations transforms some of these T cells into memory cells, which can respond quickly to defend the body against germs.

These memory cells make different types of characteristic proteins, called granzymes, which kill infected cells. They come in different "flavors," including granzyme K and granzyme B.

In a new study, published Friday (Oct. 9) in the journal Immunity, scientists found that individuals with more memory cells that make granzyme K than cells that make granzyme B tend to have healthier aging.

In the future, the balance of cells making granzyme K and granzyme B in a person's blood could be used as a test to determine "whether you're on the right trajectory of aging or not," study co-author Maxim Artyomov, an immunologist at Washington University in St. Louis, told Live Science.

Hunting for a signature of healthy aging

In earlier research, the same team found that, in old lab mice, granzyme K-making cells accumulated in several tissues and were linked to inflammation. They also observed the same increase in granzyme K cells in blood samples from older adults.

In the new study, they uncovered another piece of the puzzle: a dynamic with granzyme B-producing cells.

They began by analyzing immune cells sampled from over 2,600 people ages 18 to 97, looking at the balance of granzyme K- and granzyme B-making cells. They found that people with a lower ratio of granzyme K to granzyme B cell populations were more likely to have autoimmune diseases or other chronic immune conditions.

In a second analysis, they looked at both immune cells and blood-borne proteins sampled from 329 people, using the data to pinpoint a "protein signature" linked to an abundance of granzyme B-making cells.

They went on to hunt for this protein signature in around 48,000 participants who'd provided data to the UK Biobank, a large database of health data from U.K.-based adults. People who were predicted to have higher levels of granzyme B-making cells based on their blood proteins had worse health outcomes in the following 17 years, with a higher risk of death and of conditions like diabetes, high blood pressure, and liver and kidney disease.

The findings might point to an aspect of immune aging that wasn't previously understood.

"I think that's really exciting," Claire Gustafson, an immunologist at the Allen Institute, said of the results. "It highlights there's potentially some novel biology that we haven't really observed before," Gustafson, who was not involved in the research, told Live Science.

However, while there's a strong association between the balance of these cell populations and disease risks, Artyomov emphasized that the study does not prove that this ratio directly causes the poor health outcomes. Further studies would be needed to understand why having more granzyme B cells is linked with poorer health.

"This observation might be just a consequence, not a cause of the disease," Artyomov noted.

It's also important to note that granzyme K-making cells in mice are not the same as granzyme K-making cells in humans. In mice, they represent a more mature, specialized stage of immune cell development, whereas in humans, granzyme B cells better fit that description, he told Live Science.

That points to a key way that immunity in mice and humans is different, which was "underappreciated" before, Gustafson said. So when we're comparing these cells in mice and humans, "we're not looking at apples to apples," she said. Scientists now specifically "need to look more into humans, as it's not reflected in animal models."

In people, immune cells' features can also vary across diverse human populations, Gustafson added. We need more data across different populations to get a "true understanding of universal immune health," she said. The K-to-B ratio may be a "novel" clue that can help scientists understand healthy aging, but more data is needed to unpack why and how that ratio is linked to healthy or unhealthy aging.

"This is kind of like the first step to be able to get there," she told Live Science.

This article is for informational purposes only and is not meant to offer medical advice.

A bronze signet ring depicting the Lighthouse of Alexandria, a wonder of the ancient world, has been discovered underwater in the Mediterranean off Alexandria, Egypt.

A joint team from the European Institute for Underwater Archaeology (IEASM) and the Egyptian Ministry of Tourism and Antiquities found the artifact in the remains of a palace on the now-submerged island of Antirhodos, marking the first time a signet ring featuring the image of the lighthouse has been found, the IEASM team said in a statement.

The image on the ring is similar to depictions of the lighthouse that have been previously found on coins dating to the second century, representatives of IEASM said.

"The discovery of the ring-signet is even more important as it has been excavated in the legendary palace of the Island of Antirhodos, that once was a centre of power," Franck Goddio, president of IEASM, said in the emailed statement.

The palace was used by Egyptian pharaohs who reigned during the Ptolemaic period (304 to 30 B.C.), a dynasty of rulers descended from one of Alexander the Great's generals. The lighthouse was built on the island of Pharos around 280 B.C. and stood more than 328 feet (100 meters) tall. Some ancient writers, such as Pliny the Elder, considered it among the wonders of the world, and it continued to be used into the Middle Ages, until earthquakes and erosion resulted in its destruction and disappearance beneath the sea.

While the lighthouse was modified over time, it would have had a statue, possibly of Zeus, at the top holding an oil lamp that helped guide mariners.

Whoever was wearing a signet ring could have used it to make an impression on soft materials, such as clay and wax, to create a seal. The discovery of the ring in the remains of the palace at Antirhodos suggests that the palace was used for administrative functions related to the lighthouse, representatives of IEASM said in the statement.

Even though the ring's engraving is somewhat worn, it likely depicts the lighthouse, said Doris Behrens-Abouseif, a professor emeritus of history of art and archaeology at the University of London who has written about the lighthouse but was not part of the research team.

There are "thousands of coins from Alexandria showing a similar depiction of the lighthouse," she told Live Science in an email. Those coins date to the Ptolemaic or Roman (29 B.C. to A.D. 395) periods, she noted.

Behrens-Abouseif added that she wasn't familiar enough with rings from Alexandria to comment on whether this is the only ring that contains this image.

Other scholars told Live Science that they, too, believe that this ring depicts the lighthouse, with two scholars noting that it may feature smoke coming from a lamp at top.

The "most interesting thing about the new signet ring engraved gem is an asymmetrical feature at its peak," which "may depict a plume of smoke from the oil lamp in the hand of the crowning statue," Andrew Chugg, an independent researcher who wrote the book "The Pharos Lighthouse in Alexandria: Second Sun and Seventh Wonder of Antiquity" (Routledge, 2024), said in an email.

Margaret Miles, a professor emeritus of art history and classics at the University of California, Irvine, also noticed the possible plume of smoke. Miles noted in an email that this "ring could have been used as a signet ring by a merchant from Alexandria who used the profile of the [lighthouse] to signal his location in Alexandria. The lighthouse was famous, so it became a symbol of the city."

Research off the coast of Alexandria over the past few years, including the discovery of 22 massive blocks, has revealed more information about the lighthouse, including how exactly it looked, which is helping researchers who are trying to digitally reconstruct it.

Are you a fan of mummies and hieroglyphs? Find out with our ancient Egypt quiz!

A four-legged robot completed a full marathon on a single battery charge, covering 26.2 miles (42.2 kilometers) on a hilly public-road course in South Korea two years ago. Now we know a lot more about how it achieved this record-breaking feat.

The dog-like robot, called RAIBO2, finished the 22nd annual Sangju Dried-Persimmon Marathon in just over 4 hours, 19 minutes. The bot's developers say it's the first quadruped robot to have completed an official marathon-distance event without stopping to recharge. They're commonly referred to as "robot dogs" because the movement of their joints in both front and hind legs resembles that of canines.

The scientists outlined their findings about the robot's feat, which it achieved Nov. 17, 2024, in a study published Sept. 23 in the journal Nature.

This achievement represented a new milestone in overcoming a critical limitation for quadruped robots: endurance. Although four-legged robots can cross difficult terrain that wheeled machines struggle to traverse (like stairs and rugged trails), their endurance has been limited because powering multiple joints while repeatedly lifting and stabilizing the machine's body consumes huge amounts of energy.

"Unlike wheeled robots, quadrupeds continuously expend energy at their joints to support body weight and incur kinetic energy losses during intermittent foot-ground contact," the researchers wrote in the study.

RAIBO2's race was a demanding real-world trial. It took place during the Sangju Dried-Persimmon Marathon, with the bot racing alongside human participants. The route covered two 50-meter [164 feet] elevation climbs, with slopes of up to 10 degrees. Those kinds of gradients put increased strain on the robot's energy resources, stress-testing the bot's battery management capabilities, the scientists said.

RAIBO2 had previously run a 26.7-mile (43 km), GPS-guided route across a flat athletic field, which it knocked out in 4 hours, 40 minutes on one charge. However, an earlier marathon attempt across uneven terrain against other competitors had to be aborted around the 23-mile (37 km) mark after the robot's battery ran out. The robot's developers attributed that shortfall in part to frequent pace changes as the machine attempted to adjust to the pace of nearby runners.

To compensate, the team boosted the robot's battery capacity by 33% and tinkered with the control system, including implementing joint-stiffness control at the actuator. This allowed the bot to soften its leg when it had to absorb an impact or it needed a stable, forceful push-off. After the adjustments, RAIBO2 expanded to a maximum range of 41.6 miles (67 km) on a single charge, albeit on straight paths, according to the researchers.

Another key metric was RAIBO2's total cost of transport — a measure of the energy required to move a body over a given distance, with lower values indicating less energy expended. Researchers reported that RAIBO2 achieved a total cost of transport of 0.25, compared with a human benchmark of 0.37. The researchers said their machine was the first quadruped robot to surpass that figure.

The team attributed that efficiency to several optimizations across RAIBO2's software and hardware. Especially vital were its lightweight mechanical components, which were capable of transmitting kinetic energy from its joints with very little interference. They also credited a low-loss motor-driving circuit and, on the software side, a locomotion policy specifically streamlined to limit energy use. The system was also trained using the team's simulation environment, called RaiSim, which includes models of slopes, stairs and icy roads.

Like many electric vehicles, RAIBO2 can regenerate some battery by capturing kinetic energy, particularly while traveling downhill. That capability allows it to offset some of the energy it expends while climbing, though it doesn't eliminate the extra cost of hilly terrain.

The researchers said RAIBO2 has more than three times the travel range per charge of existing quadruped robots, with a total battery capacity of 2,016 watt-hours. It's in part because of that capacity increase that the team now estimates that the robot could travel up to 15.5 miles (25 km) farther than its marathon stint, up to a total of 41.6 miles (67 km).

That kind of endurance could broaden the roles for quadruped robots in places where wheeled models are impractical, the developers added in the study. For example, they could be useful in disaster zones and mountainous areas, where a sufficiently mobile, high-endurance robot could carry cameras, sensors or communications gear across uneven terrain.

Great Danes and mastiffs rarely live more than a decade, while Chihuahuas can live twice as long. Exactly why big dogs die younger than small ones do has been unclear — but new findings may help to solve that mystery.

The research, published Thursday (Oct. 8) in the journal Science, looked at a chemical code written on top of dogs' DNA. This code, called the methylome, consists of chemical tags called methyl groups, which bind to DNA's building blocks.

Proteins constantly access DNA, loading up the information written in its code and taking that data away to be turned into new proteins for the cell. But these methyl groups can act as tiny roadblocks that stop that process in its tracks.

These groups are one type of "epigenetic marker," which collectively help to control gene activity, and their arrangement on DNA changes predictably as animals age, study co-author Blaise Mariner, a bioinformatician at Arizona State University, told Live Science. Across many studies and species, including humans, scientists have used this data to build epigenetic clocks that track animals' biological ages.

Dogs happen to be a great species for studying aging. Their owners devotedly track what they eat, how they live, and how their health changes over time. So Mariner and his colleagues built epigenetic clocks using DNA in blood samples taken from 894 dogs enrolled in the long-term Dog Aging Project based at the University of Washington.

These samples revealed how the dogs' immune cells aged. These cells patrol the whole body, so "they're a really good measure of systemic aging," study co-author Noah Snyder-Mackler, a genomicist at Arizona State University, told Live Science.

The team found that changes in DNA methylation closely tracked biological aging, in that the dogs with older-than-expected epigenetic ages had a higher risk of death from any cause. Once they looked at how different sizes of dogs aged, clear differences emerged.

"Using our biomarker, this epigenetic clock, big dogs were aging a little bit faster per year of life than small dogs," Snyder-Mackler said.

A key epigenetic change linked to larger body size was the loss of methyl groups at stretches of DNA called transposable elements. Also called "jumping genes," these elements can potentially move around the genome, but the methyl groups help stop them from doing so. But when that methylation is lost, the jumping genes can become too active and end up damaging other genes and causing inflammation, a key process that ramps up with age.

In short, the new data suggests that out-of-control jumping genes may contribute to big dogs' faster aging.

In aging dogs, the team found that some regions of the genome with few chemical tags became more methylated, while other areas that had been choked with methyl groups gradually lost them. Additionally, at least in terms of their epigenetics, dogs' immune cells appear to become more similar to one another as they age. Mariner said this "loss of cell identity" is a key hypothesis for what happens to the body as it ages.

Immune cells are carefully specialized for different roles, such as preventing cancer or killing viruses. As these cells become more similar to one another, they become less able to fulfill their specialized roles, studies suggest.

Humans have bred big dogs for size, and Snyder-Mackler said this push for large body size may have come at a cost.

"Their bodies have to make this trade-off between really rapid growth and maintenance of that," he said, "versus investment in the immune system and integrity of the organism." For now, that idea is a hypothesis, though, as the current study doesn't directly address why big dogs' epigenetic aging has come to be this way.

Now, the team wants to build more informative clocks as the Dog Aging Project recruits more pooches to follow for longer periods. Snyder-Mackler said the team's data currently explains only part of how dogs' epigenetic ages vary. "What we really want to know is, what explains the rest of that variation?" he said.

The team was keen to build predictive models that might help dog owners anticipate their pets' age-related health concerns, Snyder-Mackler added.

What we learn about dogs from these studies may help us understand human aging, too. That's partly because dogs get some of the same diseases we do, but it's chiefly because they share humans' living spaces and environments.

"We're going to start looking, at the molecular level, [at] how these environmental exposures or experiences impact health and aging in dogs, which is going to be directly translatable to humans who are living in those same exact environments," Snyder-Mackler said.

"Most people love dogs," he added. "That means we can get a lot of really good data on them."

Researchers have discovered a roughly 9 million year old tooth belonging to a large, water-loving relative of modern day capybaras in the Atacama Desert of northern Chile. The fossilized molar adds to previous evidence suggesting that it's unlikely the Atacama, one of the driest places on Earth, was continuously dry for the last 40 million years.

The Atacama Desert, possibly the oldest desert on Earth, takes up the northern third of Chile. It's bounded by the Chilean Coast Range to the west, which blocks rain from the Pacific Ocean, and the enormous Andes to the east, which obstruct rain from the Atlantic Ocean. The driest part of the desert's hyperarid region gets less than 0.08 inches (2 mm) of rainfall a month.

Recent research estimates the Atacama's hyperarid core started forming between 47.8 million and 33.9 million years ago, in the Mid- to Late-Eocene, 20 million years before the Andes formed. It suggests the mountain ranges weren't the cause for the desert's aridification, and may have only intensified it.

Capybaras (Hydrochoerus hydrochaeris) ‪—‬ the world's largest rodent ‪—‬ exclusively live close to stable freshwater sources and feed on plants that also require water to grow, so the discovery of an extinct capybara relative (Hydrochoerus Cardiatherium) tooth in the Atacama Desert is very strange.

"Finding a capybara tooth in a marine deposit in what today is one of the driest regions on Earth is just freakish," Priscilla Martinez, a geoscientist at the University of Arizona and co-author of a new paper describing the discovery, said in a statement.

Capybaras are native to South America, although today, they are not found in Chile, where the tooth was unearthed, according to the International Union for Conservation of Nature (IUCN).

The tooth isn't the only clue that the Atacama was a wetter place in the late Miocene. Researchers found it in a layer holding the remains of a shallow marine environment that existed between 7 million and 10 million years ago, according to the statement. And they've also found microscopic pieces of plants, known as phytoliths, revealing that palm trees, grasses, gingers and other flowering plants grew there in what may have been a subtropical forest.

These findings and others are part of a growing body of evidence that the Atacama Desert was once wet enough for crocodiles and freshwater fish to thrive and palms to grow. The new study, published Sept. 5 in the journal Scientific Reports, shows that capybara relatives lived there as well during the late Miocene, which, because they are semiaquatic animals, is further evidence to support the hypothesis of a sporadically moist Atacama.

The researchers aren't sure how exactly capybaras moved into the Atacama Desert. Although there were capybaras in South America at the time, the Andes created an 18,000-foot-high (5,500 meters) barrier between their current habitats and the site where the tooth was found. The researchers theorized that, instead of traversing the mountains, the ancient capybaras migrated along the western coast of South America, following wetlands, rivers and other water sources.

According to Samantha Hopkins, an Earth sciences professor at the University of Oregon who was not involved in the study, it's unlikely the tooth found its way to the site without capybaras living there.

"If you wanted to find a way that this capybara could be here while the Atacama was still as dry as it is today, you'd have a hard row to hoe," she told Live Science in an email, because the size of the tooth makes it hard to transport it long distances. The desert wind couldn't have blown it such a long way, and while large carcasses can float down waterways for miles, "if you're going to invoke a large enough waterway to do this, you've demonstrated that the Atacama wasn't as dry as it is today anyway."

Astronomers have detected the most distant burst of radio signals ever seen: an explosion that's emitting waves of energy from more than 10 billion light-years away.

The event, named FRB 20240304B, is known as a fast radio burst (FRB). Astronomers have detected thousands of FRBs before this. But because these events last only milliseconds, they are extremely difficult to study and their origin stories remain unclear.

In this case, however, astronomers managed to use a radio telescope array and the James Webb Space Telescope (JWST) to chart the event, with JWST narrowing down the precise host galaxy that FRB 20240304B came from. The study, published Thursday (Oct. 8) in the journal Science , sheds more light on a time when the universe was only about 3 billion years old, showing that FRBs arose early in our cosmos' history. The detection more than doubles the previous distance record for FRBs.

The JWST played an instrumental role in the discovery, study co-author Themiya Nanayakkara, a senior lecturer at the Sydney Institute for Astronomy, told Live Science in an email. The email was written in collaboration with study first author Manisha Caleb, a senior lecturer in astrophysics at the same university.

For example, JWST's observations showed that the host galaxy was smaller than expected, was "metal-poor" (had few elements besides hydrogen and helium), and was forming a lot of stars. These characteristics could offer new clues about the environments in which FRBs arise, giving more information about the mysterious events. Researchers suggest that this FRB may have been linked to a magnetar, a highly magnetic star core left after a supernova.

Zooming in with the James Webb telescope

The ancient FRB was initially detected with MeerKAT, an array of 64 radio telescopes in South Africa. Nanayakkara said MeerKAT revealed "both the detection of the fast radio burst and, importantly, a very precise position on the sky."

The researchers knew the FRB was far away because of the large dispersion of the radio signal, but initial searches with powerful ground-based telescopes, "saw essentially nothing; it looked like empty sky," the researchers told Live Science. "The most likely explanation was that the galaxy was simply too faint to be detected in those observations. That is where JWST became transformative."

The science team successfully got time on JWST with a program called Director’s Discretionary Time, which is aimed at time-sensitive observations. The researchers started by using JWST's Near Infrared Camera to trace the radio signal and take a very deep image of the target region.

"Suddenly, there it was: a very faint galaxy almost exactly where we expected the host of the FRB to be," Nanayakkara said. The researchers then used JWST's Near Infrared Spectrograph to obtain a spectrum (wavelengths of light broken into different chemical signatures), which showed hydrogen and oxygen.

"These spectral features act like fingerprints: because we know the wavelengths at which they are produced in the laboratory, we can measure how much they have been shifted by the expansion of the universe," Nanayakkara explained. "That gave us a very precise redshift of about 2.15. We are therefore seeing this galaxy as it was when the universe was only around three billion years old, so roughly one-fifth of its current age."

Because the host galaxy is fairly young, it supports the idea that at least some FRBs are generated by magnetars, which are more likely to appear in spry galaxies where intense star formation is occurring, the team said.

The team plans to continue hunting for FRBs with JWST.

"We do not know what the sources will be yet," Nanayakkara said, as that depends on what pops up in the sky and is spotted by ground-based radio telescopes. "Once our radio telescopes find and localize a suitable new source, we can trigger the JWST observations. So it is quite exciting, because we really have no idea what we will find when we combine the power of these two types of telescopes."

Long before it became the luminous spiral galaxy we call home, the Milky Way was a sprawling, chaotic swarm of thousands of small galaxies, new research shows.

The findings suggest that in the first 2 billion years after the Big Bang, the region of the universe that would become our galaxy was littered with thousands of smaller galaxies of many sizes and shapes. Over time, these galaxies collided and merged into the single galaxy in which we reside today.

"Looking at these results, it's very clear that the physics happening right after the Big Bang has direct impact on what we see today in the local universe," study co-author Harley Katz, an assistant professor of astronomy and astrophysics at the University of Chicago, said in a statement.

To understand more about the early universe, astronomers build sophisticated computer models that encode the laws of nature to see how the cosmos may have evolved. The new work, which is the result of three years of supercomputer simulations, is the most detailed tracing yet of how a galaxy like ours came to be. It also arrives just as astronomers need a stronger yardstick for what they're seeing in the early universe.

Megatron, the cosmic transformer

The James Webb Space Telescope (JWST) can peer farther into the early universe than any previous telescope, and its discoveries have often defied computer models. For instance, JWST found surprisingly bright early galaxies and a mysterious new class of compact galaxies dubbed "Little Red Dots." These anomalies demonstrate that current computer models need an update to handle the complex physics of the early universe, the researchers said.

To bridge that gap, the scientists built a new suite of supercomputer simulations they call Megatron. By tracing ancient gas, starlight and chemistry from 180 million years to 2 billion years after the Big Bang, Megatron predicts the distinct light signatures of its virtual galaxies, according to the statement. Because JWST collects the same type of spectral data across a similar span of cosmic time, scientists can directly cross-reference the simulation against real observations to pinpoint what the old models are missing, the team said.

The simulation also tracks how the universe's first stars formed, died and forged the essential elements that make life as we know it possible. By comparing the simulation with JWST observations of early galaxies and with the chemical traces left in ancient stars, scientists can better understand how those first stars enriched their surroundings, the researchers said.

"Together, these complementary observations allow us to test competing models of the first stars in ways that weren't previously possible," study co-author Martin Rey, a theoretical astrophysicist at the University of Bath in the U.K., said in a separate statement.

The scientists detailed their findings in one of the six papers the Megatron collaboration published Sept. 30 in The Open Journal of Astrophysics.

Assembling the Milky Way

The team's simulation begins 180 million years after the Big Bang, when the universe is devoid of stars and galaxies and holds only pristine gas. As the next 2 billion years pass,, the model captures how the very first stars light up the dark universe and kick off "cosmic dawn," eventually culminating in those stars' violent deaths. As they die, the stars spread newly forged heavy elements such as carbon, oxygen and iron into the surrounding gas, laying the building blocks for future stars and planets.

The simulation ends 2 billion years after the Big Bang, but the Milky Way's mergers continued long after this point, and scientists are still discovering traces of the small galaxies that have joined it. The most recent massive merger, with the Sagittarius dwarf galaxy, began more than 6 billion years ago and is still unfolding.

The simulation results help scientists understand how certain physics parameters impact the early universe, and better match up JWST's observations with computer models. But it also highlights areas that need further study.

"But there are also things we're not getting right, which is interesting too — what are the parts we're still missing?" Katz said in the statement. "That can lead you into new directions and new questions."

Megatron team members in the U.K. are now developing the next generation of simulations, backed by dedicated time on the country's supercomputers. Those simulations will include more complex physics, such as active black holes, which JWST has revealed to be surprisingly common in the early universe, the researchers said.

How well do you know our home galaxy? Find out with our Milky Way quiz!

The sea surface temperature in a key section of the central equatorial Pacific Ocean has now surpassed all previous temperatures on record for this region, exceeding 86 degrees Fahrenheit (30 degrees Celsius) for the first time, according to preliminary data released Monday (Oct. 5).

Specifically, these temperatures occurred in the Niño 3.4 region, located between 5 degrees north and 5 degrees south latitude, and 120 degrees west and 170 degrees west longitude. Researchers use this region to monitor the progression of El Niño, the warm phase of a multiyear natural climate pattern that's currently in full swing and steadily intensifying. But how significant is this new record, and could it be a harbinger of increasingly extreme El Niño events in the future?

At this time of the year, sea surface temperatures above 86 F are common in the western Pacific warm pool, a mass of water located northeast of Australia. But the Niño 3.4 region is nowhere near the warm pool and usually has much cooler temperatures. This latest data indicates "an exceptionally warm state for this part of the tropical Pacific," said Jin-Yi Yu, a professor of Earth system science at the University of California, Irvine.

"If the reported daily El Niño 3.4 temperature above 30°C is verified in the observational dataset, it would be an extraordinary record," Yu told Live Science in an email.

Other experts agreed. A Niño 3.4 sea surface temperature above 86 F is a "very significant" new record, Timothy Osborn, a professor of climate science and the director of the Climatic Research Unit at the University of East Anglia in the U.K., told Live Science in an email. Mat Collins, a professor of climate systems and the head of mathematics and statistics at the University of Exeter in the U.K., also called the temperature "very significant" in an email to Live Science.

But it's important to note that absolute temperature is not the standard way of measuring the strength of El Niño, Osborn said. Researchers usually assess El Niño intensity by comparing sea surface temperatures in the Niño 3.4 region with the average conditions there or with sea surface temperatures across the rest of the tropics, with the latter method removing a skew in the data caused by the climate-change-induced heating of oceans globally.

"On those measures, the current event is already close to being the strongest [El Niño] on record and will likely soon exceed previous records given that the event is forecast to strengthen further," Osborn said. "For some measures, it is already record-breaking for the time of year."

"Super" El Niño

El Niño events happen when warm water in the western tropical Pacific Ocean migrates eastward along the equator, toward South America. This boosts global temperatures, triggering heavy rainfall and floods in regions like East Africa, southern China, the southern U.S. and the Pacific coast of equatorial South America, while places such as Indonesia, the Philippines, southern Africa and northern South America experience drought.

"El Nino impacts are greatest across the tropics and in the lands around the Pacific Ocean," Osborn said. "An El Nino with record strength is very significant because it greatly disrupts the atmospheric circulation which controls the weather patterns including patterns of rainfall."

As of Oct. 6, the temperature anomaly in the Niño 3.4 region is 6 F (3.34 C) above average and rising. A typical El Niño increases Niño 3.4 temperatures by a maximum of 1.8 to 3.6 F (1 to 2 C) above average, so the current condition is "exceptionally large," Yu said. "This indicates that a very strong, or what is sometimes called a 'super,' El Niño is developing."

This year's El Niño is being amplified by human-driven global warming, which has increased background ocean temperatures. As a result, it's likely that sea surface temperatures in the Niño 3.4 region will keep rising over the coming weeks and peak in November or December, before declining again in 2027, Collins said.

"The Niño 3.4 anomaly is very likely to remain extremely large and may increase further," Yu said, echoing forecasters' suggestions that it could reach 7.2 F (4 C) by November.

A new kind of El Niño?

The world is on the brink of crossing a critical warming threshold, raising the question of whether the current conditions can be considered a new normal for future El Niños.

While it's likely that future El Niños will be more extreme than past ones, on average, not every El Niño will be record-breaking and as dramatic as the one unfolding now, because these events tend to be very variable, Collins said.

As climate change intensifies, the big worry is that certain regions will be primed for extreme conditions even before an El Niño strikes, Osborn said. For example, regions that are getting drier due to global warming could see catastrophic droughts if they overlap with areas that experience dryness during El Niño events. Likewise, places that are getting wetter could see worse deluges of rain and flooding if they coincide with areas with higher precipitation during El Niños. But that doesn't necessarily mean extreme El Niños are the new normal, he said.

Instead, the location and duration of El Niño events may be transforming, Yu suggested. "In research by my group and collaborators, we have documented changes not only in El Niño intensity, but also in where the warming occurs and how long events persist," he said.

Yu and his colleagues helped to introduce the idea that we are seeing the emergence of two distinct types of El Niño: the eastern Pacific El Niño and the central Pacific El Niño. "Many El Niño events in the earlier observational record were dominated by warming in the eastern tropical Pacific, whereas Central Pacific El Niño events became much more prominent in recent decades," he explained, adding that El Niños have also been lasting longer.

Global warming may be creating a new kind of El Niño by strengthening atmosphere-ocean interactions in the subtropical Pacific, Yu said. If these interactions combine with processes in the equatorial Pacific, where eastern Pacific El Niños emerge, they might trigger unusually strong events with extreme heating in the central Pacific.

"That provides a physical reason to take the possibility of more frequent extreme El Niño events in a warmer climate seriously," Yu said. "But I would distinguish that from saying that every El Niño will become progressively stronger."

Cases of dengue fever are surging in Florida, spurring several counties to declare a state of emergency.

The state has seen 497 reported cases so far this year. Of those, 252, or about 51%, were caught locally, rather than brought to the state by travelers. The Florida Department of Health confirmed one woman's death from dengue fever in early September, marking the state's first known dengue death in almost a century.

Prior to the past few years, most dengue cases reported in Florida were the result of travel. In other words, people caught the disease in other countries and then traveled to Florida, where their case was then diagnosed. At 245, the number of travel-related cases reported this year is not unusually high, Caroline Waddell, a public health researcher at the University of Florida, told Live Science in an email. However, the number of cases caught from local mosquitoes is more than five times higher than at this point in the year compared with any of the previous four years, she said.

Why are local dengue cases especially high this year? Live Science spoke with experts to find out.

A growing global health concern

Dengue fever is caused by the virus Orthoflavivirus denguei, which spreads from mosquitoes to people through the pests' bites; it doesn't spread from person to person. Aedes aegypti and Aedes albopictus mosquitoes transmit the virus to humans, and the same species can also carry the viruses behind yellow fever, Zika and chikungunya.

About 100 million to 400 million dengue infections happen annually worldwide, with about 800 cases reported in the U.S. historically, although that number has increased recently. Only about 1 in 4 people exposed to the dengue virus develop symptoms, which can include fever, headache, body aches, nausea and rash. About 1 in 20 cases become severe, and immunocompromised people, children, older adults and pregnant people are especially susceptible to these serious infections.

Severe symptoms can include abdominal pain, vomiting, difficulty breathing and bleeding of the gums or nose. The most severe forms of the infection can lead to leaky blood vessels, severe bleeding, shock, organ dysfunction and death. There is no specific treatment for dengue, so care focuses on managing symptoms and maintaining patients' vital signs.

Dengue has escalated as a global health concern in the past few decades. Between 2000 and 2019, global cases of dengue increased tenfold; between 1990 and 2021, dengue-related deaths doubled. Scientists say this surge is likely driven by climate change, since rising temperatures expand Ae. aegypti mosquitoes' range, in turn exposing more people to the insects' bites. Plus, warmer conditions speed up mosquitoes' life cycles and the dengue virus's replication rate, thereby boosting transmission.

International travel also factors into these rising case counts. In 2023, dengue spikes around the world were attributed to the resurgence of global travel following the COVID-19 pandemic.

Zooming in on Florida

As the global picture has worsened, dengue cases in the U.S. have also increased.

Nearly 3,800 cases were reported in 2024 ‪—‬ an increase of more than 300% above the annual average for the previous 10 years. The uptick was tied to a rise in travel-associated cases, reflecting the wider global surge, as well as to warming temperatures that brought dengue-carrying mosquitoes to new regions of the U.S.

Each year, Florida experiences dengue outbreaks in the southernmost parts of the state, such as Miami and the Florida Keys, Panpim Thongsripong, a disease ecologist at the University of Florida, told Live Science. Historically, outbreaks in Miami typically totaled around 50 or fewer cases. But then a 2019 outbreak resulted in over 200 cases, and from 2022 to 2024, outbreak totals have ranged from about 500 to 675 cases.

The outbreak currently unfolding in Florida centers on Hillsborough County, which is farther north and includes Tampa. This is unusual, Thongsripong said, as this region of the state normally sees just a few sporadic cases. Hillsborough County has reported 223 of the state's 252 locally acquired cases this year, and it's where the one dengue-related death took place.

Florida's health department regularly traps mosquitoes and tests them for viruses. So far this year, 20 pools of mosquitoes have tested positive for dengue across seven counties, and 19 of those positive pools were sampled from the greater Tampa area. In 2025, only four mosquito pools throughout the state tested positive, and in 2023, one mosquito pool did.

"Finding positive mosquito pools is rare in Florida because dengue is not endemic to the state," said Keira Lucas, deputy executive director of the Collier Mosquito Control District. "In many ways, it can be like looking for a needle in a haystack," she told Live Science.

Routine mosquito trapping is a relatively inefficient method for detecting viruses, though, Lucas said. As such, detecting dengue-positive mosquito pools may indicate that a large amount of transmission is already unfolding. "Since approximately 75% of dengue infections are asymptomatic, the virus can circulate within a community without being readily detected for some time," Lucas explained.

In addition to Hillsborough, neighboring Pasco and Pinellas counties have declared local states of emergency over dengue.

An unlucky combination of factors

So what's driving the unusual dengue activity this year?

In the past, Florida's local dengue outbreaks tended to be concentrated in the South, which saw moderate rainfall, warmer temperatures and more travel-related dengue cases compared with the rest of the state, according to a 2022 study in the journal Insects. With the outbreak concentrated farther north this year, that could suggest changing climatic patterns are making additional parts of the state especially hospitable to mosquitoes and the virus. That wouldn't necessarily explain why Tampa is seeing more local cases than Miami this year, but it could nonetheless be a factor in the overall trend.

For the virus to persist in local mosquitoes, dengue still needs to be reintroduced periodically through travel-related cases. Because the virus is not yet endemic to the state, it doesn't regularly circulate in local mosquitoes; however, a somewhat predictable "dengue season" has been emerging that coincides with upticks in international travelers carrying the virus to Florida.

This year, though, the high number of locally acquired dengue cases suggests a shift from predominantly imported infections toward outbreaks spurred by local Florida mosquitoes. Scientists hypothesize that climate change could increase local transmission in Florida even more in the future.

This year, Florida has also been enduring its most intense drought in over a decade. In theory, that might be expected to limit mosquito populations because the pests need water to breed, Lucas said. However, when it's dry, people tend to run their sprinklers more, creating mosquito breeding grounds when puddles form or containers fill up, she noted. This could bring mosquitoes closer to people, as it creates opportunities for them to breed.

Ae. aegypti mosquitoes are especially well adapted to living alongside humans, as they prefer to breed in human-made containers. Droughts can also drive dehydrated mosquitoes to bite more as they hunt for fluids.

"It's almost like an unlucky [combination]," Thongsripong said. "Everything coming together at the right time and right place, and boom, you have the conditions for an outbreak to occur."

The true number of dengue cases may be even higher than reported, Waddell said. The cases captured in the data include infected individuals who went to a doctor to get tested. Because many infections are mild or asymptomatic, additional people may have contracted the virus but never got counted.

What can be done

It's too early to definitively say what factors have increased Florida's dengue cases this year, Thongsripong said, as scientists are still gathering information. Despite the unknowns, she thinks the health and housing infrastructure in the U.S. will stop dengue from becoming too dangerous here.

To get dengue under control, it's key for government-level mosquito control efforts to coordinate and for the public to be aware of the virus, Lucas said. The mosquito control district coordinates with the health department for the latest data to best target where to spray larvicide, which kills mosquito offspring before they can bite people, she said.

It's important for people to use mosquito repellent when going outside, Thongsripong said, as well as to empty water from objects that can collect water and become a mosquito breeding ground, such as pets' water bowls, plant saucers, buckets or discarded tires.

Due to this year's strong El Niño, Florida is expecting a rainier winter, which could mean even more mosquitoes than usual, Lucas noted. That, in turn, could fuel additional dengue cases.

"Cases with September onsets are still being reported," Waddell said, "so we're not out of the woods."

This article is for informational purposes only and is not meant to offer medical advice.

OpenAI representatives claim that the recent launch of one of its latest models, GPT-6 Astra, marks the beginning of the artificial general intelligence (AGI) era — a hypothetical scenario in which artificial intelligence (AI) can learn and reason like humans. Following very recent claims from technology executives that we've now reached this milestone, how likely is this claim to stand up to scrutiny?

Amid revelations that safety concerns have forced the company to abandon the planned rollout of GPT-6.1 Astra, independent researchers and benchmark creators warn that GPT-6 Astra's record-breaking scores rely on heavy prompt optimization rather than true general intelligence. This comes as experts warn about the risks of future AI systems and AI executives jointly call for a slowdown in AI research.

In announcing the model's release, OpenAI President Greg Brockman suggested that Astra signaled a fundamental turning point in AI evolution. "If we fast-forward a couple years, and we look back and say when was it really that AGI was created, I think it's going to be about this time, and I think it might be about this model," Brockman said during a Sept. 3 news conference marking the launch.

How did the new model perform in benchmarking?

As part of the testing-and-verification process for the new model, OpenAI released benchmark results across a range of tests that measure the capabilities of AI models at various tasks. OpenAI representatives claimed in a statement that the company's new model delivers "state-of-the-art" performance across a variety of fields, including software engineering, the autonomous use of computer programs, mathematics problems, and even scientific research.

Demonstrations, for example, highlighted Astra's ability to generate 3D CAD code; lay out printed circuit boards in CAD (computer-aided design) software; convert digital 3D models into interactive, video-game-style environments; and deploy hosted web applications directly from prompts.

"In our early testing, Astra stood out by approaching legal work the way a discerning lawyer does: it distinguishes documents from established records, surfaces unsupported assumptions, and converts gaps into concrete drafting positions," said Niko Grupen, head of applied research at legal services AI developer Harvey as part of OpenAI’s announcement.

On ARC-AGI-3 ‪—‬ a benchmark designed to measure how efficiently AI systems acquire new skills in novel, abstract environments ‪—‬ Astra achieved a headline score of 99.9%. Independent testing by the nonprofit ARC Prize Foundation, which oversees the benchmark, revealed that Astra surpassed "human action-efficiency" baselines on 96% of levels, taking 51.7% fewer actions per level, on average, than human solvers.

"Not only is this the best model we've ever tested," ARC Prize Foundation President Greg Kamradt said as part of the OpenAI announcement, "but it also represents a meaningful step change in frontier-model performance — not only in its ability to navigate and solve novel environments but also in how efficiently it learns to do so."

How much can we read into test results?

Many researchers have highlighted that Astra's top ARC-AGI-3 performance relied on a proprietary "Provider Adapter" harness, a specialized software scaffolding layer that's inaccessible to rival developers. When tested using the benchmark's neutral Standard harness, this score dropped to 62.7%. ARC Prize organizers also noted that saturating the benchmark does not constitute proof of achieving AGI — emphasizing that its closed, deterministic puzzle environments do not capture the open-ended complexity of the real world.

"When we launched ARC-AGI-3, "we made it clear that saturating the benchmark would not represent 'proof of achieving AGI,'" Kamradt wrote in a blog post. "Therefore, while we believe Astra represents meaningful progress towards generalization, we are not claiming that it is AGI."

Discrepancies in the data were reportedly present even before the official announcement. As reported by Fortune, an embargoed draft provided to news organizations prior to the model's launch listed Astra's ARC-AGI-3 score at 98.6% before it jumped to 99.9% on the live site.

Anka Reuel and Mike Hardy, doctoral researchers in AI at Stanford University, also raised concerns over OpenAI quietly revising several published metrics post-launch, including halving Astra's reported hallucination rate from 4.2% to 2.0% before reverting it.

Speaking to Fortune, Reuel and Hardy attributed the shifting figures to "benchmaxxing" — an industry term that describes the practice of repeatedly rerunning evaluations under subtly tweaked prompts, scaffolds or compute allocations to hunt for peak theoretical scores.

In a 2025 paper published on pre-print server arXiv titled ‘Benchmarking is Broken -- Don't Let AI be its Own Judge’, experts including Princeton doctoral candidate Zerui Cheng and University of Luxembourg postdoctoral researcher Dr. Stella Wohnig warned that such practices create confusion and undermine trust, particularly when official technical documentation omits the basic methodology, making independent verification nearly impossible. Crucially, scores achieved through benchmaxxing reflect idealized performance ceilings under optimal lab conditions rather than practical, out-of-the-box reliability.

According to OpenAI's benchmark data, across specialized domain evaluations, GPT-6 Astra delivered 10% to 20% better performance than both its predecessor, GPT-5.6 Sol, and top market competitors.

Highlights include a 98% score on FrontierMath Tier 4 (v2), which evaluates expert-level mathematical reasoning; a perfect 100% on ExploitBench, which is designed to test offensive cybersecurity capabilities; 95.9% on BenchCAD, which measures an AI's ability to reconstruct 3D objects using CAD code; 57.9% on Terminal-Bench 4.0, which assesses complex terminal-based system administration and software engineering; and 41.4% on AutomationBench, which tests whether agents can complete multistep business workflows across applications.

But independent findings from external AI benchmarking firm Artificial Analysis contradict these results. Astra's score on the independent Artificial Analysis Intelligence Index — an aggregate metric that evaluates general reasoning across frontier models — remained completely flat, at 61, compared with GPT-5.6 Sol, while trailing competitors like Anthropic's Claude Fable 5.1 and Meta's Muse Spark 1.3.

While some benchmark results have seen improvement since the previous generation, Astra underperformed in other tests. Artificial Analysis' testing showed that against GDPval-AA v2 — an economically focused benchmark that measures real-world workplace tasks across 44 occupations — Astra suffered a significant drop in its relative leaderboard ranking compared with GPT-5.6 Sol. Additional regressions were observed in benchmarks that test customer service support, scientific Python programming, and long-context reasoning across large documents.

In terms of overall token use — the metering system that measures the fragments of text or data processed by AI models — OpenAI representatives said GPT-6 Astra achieved dramatic efficiency gains on complex, long-horizon tasks. Findings from Artificial Analysis confirmed that on software engineering benchmarks, Astra was approximately 70% more token-efficient than GPT-5.6 Sol, using roughly one-third the total tokens of its predecessor and one-fifth the tokens of Claude Opus 5.

On professional workplace evaluations like Agents' Last Exam, the new model reduced output token consumption by up to 65% compared with Opus 5, while on general intelligence evaluations, Astra achieved a roughly 10% output token reduction at max effort compared with Sol.

On the other hand, this achievement is offset by a 250% increase in the base API pricing for GPT-6 Astra compared with GPT-5.6 Sol. Token prices jumped from $4/$20 to $10/$50 per million input/output tokens. As a result, Astra ends up approximately 75% more expensive per task than its predecessor on general intelligence evaluations, despite using 10% fewer output tokens. This trade-off has led researchers at Artificial Analysis to question whether AI labs are relying on expensive computational brute force to squeeze out minor gains, rather than achieving true technical breakthroughs.

Does achieving AGI even matter?

With its latest model, OpenAI has placed a stronger emphasis on safeguards and controls. The move follows a series of high-profile incidents in which frontier AI models inadvertently hacked into third-party networks and computer systems as part of routine testing operations, after the models went beyond what humans expected they would do when encountering challenging tasks.

According to OpenAI representatives, Astra did not exceed the scope of its tasks in any security evaluations. For comparison, GPT-5.6 Sol went beyond its authorized parameters in almost 50% of test cases. Hallucination rates have also been reduced significantly, falling to 4.2% on internal tests, compared with 12.2% for GPT-5.6 Sol (with independent testing by Artificial Analysis showing a drop from 92% to 51% at max effort). The model also showed an improved ability to handle ambiguous prompts.

David Wood ‪—‬ chair of London Futurists, a non-profit that hosts discussion groups on emerging technology ‪—‬ argued that beyond individual test results, Astra highlights a fundamental shift in how humans will interact with AI as models move from answering questions to autonomously pursuing complex goals in digital environments.

"The impressive benchmark results matter, but what matters more is the combination of intelligence, autonomy, computer use, and cybersecurity capability," he said in an email to Live Science. "That combination also demands caution. The more useful these systems become, the greater the consequences when they misunderstand our intentions, are misused, or find ways around the safeguards we give them."

Wood suggested that whether Astra can be classified as AGI is less relevant than recognizing the need for AI control and governance to keep pace with technical development.

"The possibility that AI could progress from systems like Astra towards all-round superintelligence makes much greater human vigilance, awareness, and collaboration increasingly urgent," he said.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

The remote south Atlantic island of St. Helena boasts an international celebrity: the tortoise Jonathan, the oldest living land animal. At 194 years old, he has outlasted the expected lifespan for an Aldabra giant tortoise (Aldabrachelys gigantea) by about a century. Now, scientists have identified a range of unique genetic and epigenetic traits that may hold the key to this longevity.

The new research zoomed in on Jonathan's genes, as well as the chemical tags that sit on top of DNA molecules, known as "epigenetic markers." These markers help control which genes are activated and to what degree. The analysis finds that Jonathan's genes associated with mitochondrial function are in great shape, epigenetically speaking, which suggests that they've played a big role in the tortoise's success.

While mitochondrial function has long been linked to longevity and mitochondrial dysfunction has been tied to disease, Jonathan offers fresh insight into that dynamic, said study co-author Stephen Clark, chief scientist of the Kallel Foundation, a nonprofit in Nashville researching drug targets to promote human longevity.

Clark and colleagues published their findings Wednesday (Oct. 7) in the journal Science Advances.

Decoding Jonathan's secrets to long life

Nearly a decade ago, the researchers enlisted Joe Hollins, the vet tasked with Jonathan's care, to collect samples from the record-setting animal. Island authorities forbade the vet from drawing the tortoise's blood, fearing the risk of an infection.

"I didn't want to be the doctor that killed Jonathan," Clark told Live Science. Hollins collected samples via cheek swab instead.

When the samples arrived in the U.S., the researchers sequenced them, but when their computers kept crashing, they discovered that the DNA had been isolated from bacteria in Jonathan's mouth rather than the tortoise's own cells.

Clark "had to go back and beg" for permission to collect more data, he said. The vet then sent cheek scrape samples, which are collected with a slightly different tool than cheek swabs. This time, the DNA was in fact from Jonathan.

The DNA isolated from those cheek tissue samples was more fragmented than it would have been in a blood sample, so the researchers filled in the gaps using an existing reference genome from a 36-year-old Aldabra tortoise named Tank. They also compared Jonathan's DNA to that of a Galápagos tortoise (Chelonoidis abingdoni) named Lonesome George, who was believed to be over 100 years old at the time of his death in 2012.

The team found that, compared to Tank and Lonesome George, Jonathan carried 287 unique variants of genes that had previously been linked to aging-related pathways. These included genes involved in DNA repair and the function of telomeres — the protective tips at the end of chromosomes that tend to shorten with age.

These pathways are also related to aging processes in humans, highlighting a "broader signature of aging" across species, Greer Dolby, an assistant professor of biology at The University of Alabama at Birmingham, who was not involved with the study, told Live Science.

The researchers also looked at epigenetic changes, including DNA methylation, which is when a chemical tag called a methyl group binds the DNA. Certain patterns of DNA methylation can function as a "clock" in that they reflect an organism's biological age; scientists have recently harnessed these patterns in the study of human aging. In this case, the team compared the DNA methylation across Jonathan's genome to that of young and old Aldabra tortoises.

The methylation patterns were more disordered in the older tortoises, reflecting random changes acquired over time, the researchers found. Scientists call this phenomenon "methylation entropy." For most genes, Jonathan's DNA methylation patterns were more disordered than those of the young tortoises. But in a suite of genes tied to mitochondrial function — specifically the bits of those genes that switch them "on" — Jonathan had more organized methylation patterns. That might keep expression of these genes consistent over time, the researchers theorized.

Mitochondria produce energy that cells need to function properly, repair themselves and reduce further damage to DNA. "Keeping the entropy low in these mitochondrial genes, or keeping pristine mitochondria, is likely to be a contributor to longevity," Clark said.

However, the authors couldn't determine a causal relationship — they didn't run any tests that could definitively prove that Jonathon's lack of entropy in these genes explains his long life. Clark argued that additional experiments on a blood sample from Jonathan could offer a more comprehensive view of his genome.

Jonathan's full genetic profile can't be known until after the tortoise's death, when researchers can collect DNA from more tissues, said Vincent Lynch, a professor of biology at the University at Buffalo, who was not involved with the study.

"Some organs are more susceptible to different diseases of old age than other ones, and that happens because mutations accumulate over time," he told Live Science. "We would ideally like to know what those mutations are in those specific tissues."

Furthermore, Lynch questioned whether entropy was a useful characterization of age-related DNA methylation patterns, as methylation can be unpredictable. That said, he agreed that the genes flagged in the study offer helpful data for future work on longevity.

More experiments are needed to determine whether these mitochondrial genes actually play a role in longevity across all Aldabra tortoises, let alone in other animals, or if Jonathan is just an outlier.

"Maybe Jonathan is just really good at being old," Lynch said.

A newly discovered platypus-like creature is the largest-known mammal relative from the entire Jurassic period, a new study finds — although it still only weighed as much as a Chihuahua.

The critter, which hunted salamanders in the freshwater lakes and rivers of what is now Inner Mongolia, China, lived during the mid-Jurassic between 168 million and 163 million years ago. It seems to be the earliest known mammal-type animal that lived a semiaquatic life.

Researchers unearthed the delicate and detailed fossil in 2016, which revealed that the animal likely weighed about 2.2 to 4.4 pounds (1 to 2 kilograms). It was large for a mammal relative during the Jurassic, but its name, Megacauda sungei, was inspired by its tail: Megacauda means "big tail." The discovery was detailed in a study published on Wednesday (Oct. 7) in the journal Nature.

The furry predator had a mix of features seen in modern-day animals, with a broad, flattened tail that marks it as a powerful swimmer, and short hind legs with relatively long feet.

"It's like a chimera," study co-author Zhe-Xi Luo, a paleontologist at the University of Chicago, told Live Science. "The back half of this animal is very much like a platypus. As are the limbs, which would be capable of swimming or digging tunnels in river banks."

But the teeth "are definitely not like a platypus," Luo said. It possessed robust canines and shearing cheek-teeth that would cut and chew meat in a different way from modern carnivorous mammals. "It's a predator with gigantic and very specialized canines," Luo said. "So, it's partly otter-like and partly platypus-like."

A revealing fossil

Tiny bits of vertebrate bones found in what would have been the animal's stomach and the surrounding fossil beds hint that M. sungei dined on salamanders, Luo said.

He added that M. sungei may have sheltered in burrows on land in the temperate plant-filled climate, and hunted in lakes and rivers for fish and invertebrates.

Another notable aspect of the fossil is its throat. Modern mammals, including humans, have hyoid bones in the throat arranged in a "U"-shaped saddle. These help us use throat muscles to swallow chewed food one chunk at a time, instead of gulping down huge bites or whole prey. The structures also enable babies to suckle their mother's milk.

M. sungei seems to have had the apparatus needed to do this, study co-author Thomas Martin, a paleontologist at the University of Bonn in Germany, told Live Science.

"This is an incredibly important evolutionary innovation," Luo said, adding that this capability is one of the things that helped early mammals diversify into carnivores, insectivores, herbivores or omnivores to take advantage of all sorts of foods.

Finding this in M. sungei suggests that the apparatus needed for suckling milk and swallowing had already evolved by the Middle Jurassic (around 174 million to 164 million years ago), Martin said.

This is before marsupials like kangaroos and placental mammals like primates and bears are thought to have diverged from each other 160 million years ago, after descending from an egg-laying common ancestor that lived approximately 180 million years ago.

"Now we push the history of it back to before the split of modern marsupials and modern eutherian [placental] mammals," Luo said.

"Neonatal suckling behaviour was previously thought of as being a hallmark of advanced mammals, but it now appears to have evolved well before then, in the common ancestor of docodontans and mammals at least 165 million years ago," said Sue Hand, a vertebrate paleontologist at the University of New South Wales in Australia who wasn’t involved in the study.

M. sungei is from an extinct lineage of docodonts, which are relatives of mammals from the dinosaur-dominated Jurassic and Cretaceous periods, living between about 200 million and 120 million years ago.

Docodonts adapted to a wide variety of habitats. For example, there was the Jurassic tree-dwelling shrew-like docodont called Microdocodon gracilis, and Docofossor brachydactylus, a tunnel-digger with shovel-like paws. Luo was also part of the team that described a semiaquatic "Jurassic beaver", Castorocauda lutrasimilis, which lived 164 million years ago.

"It seems that an aquatic lifestyle arose often in early mammal-like species," said Tim Flannery, a mammalogist at the Australian Museum Research institute who wasn't involved in the work.

If anything, the newly described "spectacular fossil" shows that docodonts were wide-ranging during the dinosaur age, Hand told Live Science in an email.

"This very detailed study adds to accumulating evidence that mammaliaforms occupied a wide range of ecological niches long before the evolution of living mammals," Hand said.

A 1,000-mile-long (1,600 kilometers) Martian cloud that emerges and then quickly disappears from the Red Planet's sky nearly every day is even weirder than scientists realized. New simulations suggest that the eerie apparition can only be explained using "exotic physics" that have been theorized but never seen on Earth or anywhere else in the solar system.

The mysterious floating mass, dubbed the Arsia Mons Elongated Cloud (AMEC), frequently emerges above Arsia Mons, a 12-mile-tall (20 km) extinct volcano located in the Tharsis region, just south of the Red Planet's equator. The water vapor cloud was first spotted in 2018 by the European Space Agency's Mars Express orbiter and has since appeared nearly every morning throughout Mars' spring and summer, when increased solar radiation triggers strong surface winds. But it lasts only a few hours each day, before fully evaporating.

The AMEC can stretch up to 1,100 miles (1,800 km) long, around one-twelfth of Mars' circumference. For context, that is roughly twice the length of the U.K. or the distance between New York City and Miami.

Although the Red Planet is no stranger to giant dust clouds and occasional "iridescent streaks" of carbon dioxide, it is almost completely devoid of atmospheric water vapor. That makes it extremely rare for puffy, Earth-like clouds to form there, let alone ones so vast. As a result, scientists have struggled to explain this whacky weather.

But in a new study published Wednesday (Oct. 7) in the journal Nature Geoscience, researchers used Mars Express data to create new simulations in an effort to finally explain the AMEC. Initially, the team struggled to recreate the puzzling phenomenon. But when they abandoned traditional meteorological principles in favor of a more out-of-the-box explanation, they were eventually successful.

"To create the AMEC in our modelling, we found that we needed to include some exotic physics … physics that, while included in textbooks, is treated as theoretical and usually thought not to happen in nature," study first author Jorge Hernández-Bernal, a planetary scientist at the University of the Basque Country in Spain who was affiliated with Sorbonne University in Paris at the time of the study, said in a statement. "Once we included this physics in our simulations, the AMEC emerged just as we hoped."

"Wholly unexpected"

The AMEC is an orographic cloud, meaning it forms as strong winds push water vapor up and over a raised structure, such as a mountain. Similar clouds also exist on Earth, including the "Levanter" cloud, which occasionally forms above the Rock of Gibraltar in southern Europe. However, the Martian equivalent cannot be explained by the same processes that occur on our planet.

On Earth, clouds form via a process called heterogeneous nucleation, in which moist air cools and condenses into ice crystals that form around tiny atmospheric particles, such as dust, salt, pollen or soot. But while Mars has plenty of atmospheric dust, that's not what's happening there.

"For the AMEC, it seems that cloud formation takes place without needing any of this 'stuff' [in the air]," said Hernández-Bernal, who has been studying the AMEC for the past six years. "Water vapour turns directly into icy cloud particles without any middle step. It's akin to droplets of condensation appearing in the middle of a room, rather than on a window."

The researchers call this "homogeneous nucleation" and say it has never been seen before in a planetary atmosphere. "It's wholly unexpected," Hernández-Bernal added.

Other scientists previously predicted that homogeneous nucleation could occur in Earth's upper atmosphere or in the skies above Venus. However, this has been deemed highly unlikely because it requires humidity levels roughly 100,000 times greater than those on our planet's surface.

Given that modern-day Mars is almost completely devoid of water, it may seem unlikely that its humidity levels could reach such lofty heights. However, the Mars Express data tells a different story.

As wind rises up the slopes of Arsia Mons, which is more than twice as tall as Mount Everest, it creates a powerful wave that shoots air into the upper atmosphere at tremendous speed. The researchers calculated that the temperature of this air can drop by up to 54 degrees Fahrenheit (30 degrees Celsius) in just 10 minutes. This not only makes it easy to freeze but also greatly increases the humidity within the wave, allowing homogeneous nucleation to take place, the simulations show.

So where does all this water come from? Some of it is already in the atmosphere, but some likely originates at the summit of Arsia Mons, which is covered with a thick layer of frost, the researchers suggested.

"A big success"

The new simulations mark a big step forward in our understanding of the AMEC and wider Martian meteorology.

"We don't have nearly as much information about Mars' atmosphere as we do about Earth's, so reproducing the AMEC to this degree is a big success for the model," Hernández-Bernal said.

The findings would not have been possible without the Mars Express orbiter, which used three instruments — the Visual Monitoring Camera, the High Resolution Stereo Camera and the OMEGA instrument — to map out how the AMEC takes shape and evolves every day. It is also one of the only Mars spacecraft that can see Arsia Mons in daylight.

"Mars Express discovered the AMEC, has followed up and monitored it for years, and is now helping reveal the secrets of its formation," Colin Wilson, the project scientist for Mars Express, who was not involved in the new study, said in the statement.

The discovery is also a reminder that, despite sharing the same basic principles, weather systems do not behave the same on other worlds as they do on Earth, which could have big implications for solar system exploration and the hunt for extraterrestrial life on distant exoplanets.

"While clouds on Earth and Mars seem to be governed by the same 'rules', understanding this exotic Martian cloud required exotic physics — and this may be true elsewhere in the cosmos," Wilson said.

Astronomers have spotted a never-before-seen type of "phoenix planet" rising from the ashes of a dying alien sun. The discovery, which the scientists say was "completely unexpected," raises hopes that more of these reborn alien worlds could be lurking throughout the cosmos — and may offer a glimpse of our own solar system's fate.

The unnamed exoplanet was spotted circling the white dwarf HS 0209+0832, which is located roughly 270 light-years from Earth. White dwarfs are stellar remnants, sometimes dubbed "zombie stars," that form from the leftovers of massive red giants that run out of fuel before eventually collapsing into shriveled husks. HS 0209+0832 is a particularly young white dwarf, still burning at around 63,000 degrees Fahrenheit (35,000 degrees Celsius), which suggests it made this transition within the past few million years.

Scientists previously discovered some surprising heavy elements within the visible spectrum of HS 0209+0832, which was first captured by the Hubble Space Telescope in the late 1990s. These elements ‪—‬ which included aluminium, titanium and nickel ‪—‬ are not normally found inside white dwarfs, so their presence suggested that something unusual was going on. But until now, there was not enough data to figure out what.

In the new study, published Oct. 5 in the journal Nature Astronomy, researchers took a closer look at HS 0209+0832. Using some of Hubble's updated instruments and data from other observatories, the team captured a more detailed spectrum of the stellar zombie. This revealed a high concentration of additional heavy elements, including zinc and copper, as well as niobium, which has never been seen in a white dwarf before.

The researchers think these out-of-place elements were created during the death throes of the former red giant and later coalesced into a "second-generation" planet around the newly forged white dwarf. They suspect the atmosphere of this hypothetical planet is being stripped by the white dwarf's stellar winds, causing the rare elements to fall back onto the zombie star.

Follow-up observations then revealed a recurring dip in the brightness of HS 0209+0832, suggesting that an exoplanet was repeatedly passing in front of the undead star. Based on the alien world's orbit, which lasts approximately 4.4 Earth days, and the duration of its transits in front of the star, the team predicted that the planet is roughly the size of Jupiter. (Its close proximity to the white dwarf also supports the hypothesis that its atmosphere is being stripped away.)

"Second-generation planets are worlds that form out of the material a star casts off as it dies," study first author Jamie Williams, a doctoral candidate in astronomy and astrophysics at the University of Warwick in the U.K., said in a statement. "They're incredibly rare, and finding one around a white dwarf was completely unexpected. It's a bit like finding a planet that has risen from the ashes of the very star it once orbited."

"Completely unexpected"

This is not the first time astronomers have spotted an exoplanet around a white dwarf. For example, in 2019, some of the authors of the new study previously spotted an alien world surrounding the white dwarf WDJ0914+1914. However, in that case, they were confident that it was a first-generation world that somehow survived its star's fiery end.

But the heavy elements that seem to be falling onto HS 0209+0832 — and the relative lack of other elements common in first-generation planets, such as silicon and iron — suggest that's not what's happened for this recently detected world.

"This pattern of elements is a telltale sign of the 's-process,' a nuclear reaction that builds heavy elements inside dying stars during their bloated red giant phase," study co-author Nicholas Stone, an astronomer at the University of Wisconsin-Madison, said in the statement. "It's a chemical signature no ordinary, 'first-generation' planet should carry, which told us that this new planet was something different."

Instead, the newly detected exoplanet likely formed directly from the material that was shed by the dying red giant after it expanded and before it collapsed in on itself.

Similar phoenix planets have been spotted alongside other stellar remnants, such as pulsars, which form when stars explode as supernovas. However, until now, such worlds have never been seen around a white dwarf.

Rising from the ashes

"What's remarkable about the planet around HS 0209+0832 is that this isn't a planet from somewhere else, or a survivor from the system's birth, it looks like it was built from the very material its own star cast off as it died," study co-author Boris Gänsicke, an astrophysicist at the University of Warwick who also helped to discover the exoplanet around WDJ0914+1914 in 2019, said in the statement. "In a sense, this system has given birth to a new world using the foundations of the old one."

HS 0209+0832 may have once harbored other exoplanets when it was a red giant. But if they existed, these alien worlds likely perished in flames as the dying star ballooned — similar to what experts think will happen to Earth when the sun runs out of fuel and transitions into a red giant in around 5 billion years.

Once the sun has finished bulging, it will turn into a white dwarf too. The new discovery hints that our star could also host brand-new worlds after it has transformed, creating a sort of solar system 2.0.

"Finding this one example raises the question of how many more might be out there and might our own solar system host a second-generation planet formed from the ashes of our sun," Gänsicke said.

However, more work is required to figure out exactly how the newfound exoplanet formed and, as a result, how likely this scenario is. The researchers suspect that another object, such as a lost stellar sibling, may have been required to create the new world.

"Forming the protoplanetary disc in this situation is not easy and helps explain why these planets are so rare," Williams said. "To form a disc of material necessary to birth a planet, HS 0209+0832 likely required a companion star that pulled the ejected material back into orbit, rather than letting it escape."

Have you ever wondered what it's like to be flipped off by an orangutan or seduced by a mantis? Well, wonder no more, thanks to the 2026 Nikon Comedy Wildlife Awards.

This photography competition showcases the amusing side of nature, usually by anthropomorphizing it in some way, and features a variety of comical critters from across the globe.

This year, a surprised owl and a brown bear striking a pose are featured among the more than 10,000 entries, with photographers competing for a luxury safari in Kenya's Maasai Mara National Reserve.

Live Science rounded up some of the funniest photos from the 2026 finalists for your enjoyment. And yes, the orangutan and mantis have made it to the finals.

"Are You Kidding Me?"

Here we see a squirrel launching itself at a great horned owl fledgling in Natural Bridges State Beach park in Santa Cruz, California. According to photographer Kevin Lohman, the squirrel knocked the owl off its perch three times.

Our video channels editor, Elise Poore, said this photo really made her laugh. I doubt the owl found it quite so funny. However, great horned owls (Bubo virginianus) do hunt squirrels, so it's no surprise that these rodents can get a little tetchy around the birds.

"Spicy Orangutan"

This "Spicy Orangutan" entry features a male Bornean orangutan (Pongo pygmaeus) raising one finger, giving the appearance that he's flipping off the camera. In the description accompanying the image, photographer Tanner Mansell explained that the orangutan was finishing his meal at the time.

"Even though he was completely wild and just enjoying his food, I couldn't help wondering, 'Does he know what he's doing?'" Mansell wrote.

No, Mansell, he doesn't.

"Ballet Dancer"

This photo of a sparrowhawk (Accipiter nisus) in Dumfries, Scotland, is titled "Ballet Dancer," but to me, the balancing bird looks more like an Olympic gymnast in the middle of a complex beam routine. Either way, perfect form!

"Push Over"

This lion snapshot, taken in the Ruckomechi riverbed in Zimbabwe, is one of many finalists that appear to show animals laughing or joking around.

"#ForTheGram"

Photographer Rosie Barrett was getting shots of three yearling brown bears (Ursus arctos) in Finland when one appeared to strike a pose.

"Pretty sure he knew it was for Instagram..un-bear-lieavable!" Barrett wrote in a description of her photo.

S-bear me.

"Sexy Mantis"

I know what you're thinking: This mantis looks like it's saying, "Draw me like one of your French girls." However, if you can look past the sexualization of an insect, you might notice a pretty neat trick in how the photo was framed.

Half of the mantis's body is hidden behind the leaf. What appears to be a torso and legs are actually the creature's forelimbs, which it uses to catch prey. Photographer Diego Perez explained that he snapped the mantis while documenting wildlife in the proposed Bosques del Araza Regional Conservation Area in Peru, which is currently threatened by illegal gold mining.

"Sea Gangsters"

Here we see a herd of walruses on the coast of Svalbard in Norway. The photo is titled "Sea Gangsters," implying that the walruses look like tough guys. You'd probably feel tough, too, if your tusks (which are actually sabers) grew to around 3 feet (1 meter) long.

"Little Godzilla"

Ten out of 10. No notes. But, in all seriousness, red squirrels (Sciurus vulgaris) are known to grab materials like dried grass and moss to line their nests, called dreys, so maybe this little fellow is working on its home sweet home.

"The Different One"

Sometimes, all a photographer needs is the Maasai Mara, three young giraffes and a perfectly placed acacia tree. It's nice that the photographer caught them at a standstill, since these ungulates can run up to 35 mph (56 km/h) in short bursts.

This is just a selection of the finalists. You can see the rest of the contenders in Nikon's 2026 finalists gallery. The winners will be announced Dec. 8.

What do you know about the animal kingdom? Test your knowledge with our animal quiz!

The Draconids, one of the year's most unpredictable meteor showers, will peak this week. Although only a few "shooting stars" are expected, the shower has a history of producing spectacular meteor storms with little warning.

The Draconid meteor shower takes place Oct. 6-10 each year, peaking on Oct. 8-9, when around 10 "shooting stars" per hour are expected. Whereas most meteor showers are best seen after midnight or during the dark hours before dawn, the best time to view the Draconids is in the evening, according to Timeanddate.com, making it one of the more convenient meteor showers of the year. Just after dark Thursday (Oct. 8) will be the best time to look.

The Draconids are different from most other showers because their radiant — the point from which their meteors appear to originate — is in the constellation Draco, the Dragon, which is highest in the sky in the evening. It's also circumpolar in much of the Northern Hemisphere, so it never sets below the horizon. However, there's no need to stare directly at Draco, because meteors can appear anywhere in the sky.

This year, the Draconid meteor shower peaks at the perfect time of the month for dark skies. Because the new moon occurs Saturday (Oct. 10), there will be no significant moonlight when the Draconids reach maximum activity.

However, the Draconids are notoriously unpredictable; while just a handful of meteors per hour are expected, the shower can sometimes produce huge meteor storms. For example, during the Draconids' peak in 1933, Europe saw 500 meteors per minute, according to NASA, and during the 1946 peak, 50 to 100 meteors were seen per minute in the U.S.

The source of the Draconids is Comet 21P/Giacobini-Zinner, which was discovered in 1900 and orbits the sun every 6.6 years. It was last in the inner solar system in 2025 and will return in 2031.

Each October, Earth passes through streams of dust and debris left along the comet's orbit. When those tiny particles strike Earth's atmosphere, they heat up and vaporize, creating streaks of light in the night sky.

Most observers will probably see only a few Draconids this year, but with a meteor shower this unpredictable, it's always worth looking up. The best way to see the Draconids is with the naked eye, but a good pair of stargazing binoculars or a nice backyard telescope will help you enjoy the feast of fall skywatching events on the horizon. Amazon has great deals on skywatching gear this week, so it's a perfect time to get involved.

Emerging treatments aim to reverse or stall signs of aging in the body and thus cut the risk of age-related diseases. One of those signs is an accumulation of "zombie cells" — damaged cells that spew harmful substances rather than dying off and getting cleared away by the immune system.

Some scientists are designing treatments aimed at killing those zombies directly. But what if we instead helped the body's cleanup crew get rid of them?

"I think rejuvenating the immune system could rectify a lot of problems," said Roel de Maeyer, an immunologist at the University of Oxford. "We know hospitals are full of older people suffering from infections that younger people don't need to go to [the] hospital for."

The aim of these rejuvenating therapies would be to help people live healthier for longer, he told Live Science.

How do cells turn into zombies?

The immune system constantly gets rid of old, dysfunctional and dead cells to keep tissues healthy, but that cleanup gets less effective with age.

When cells die, they display proteins on their surfaces that act as "eat me" signals for immune cells, called macrophages, to engulf and destroy them. However, some cells refuse to die and instead become senescent. These zombified cells can lurk in tissues for years, releasing chemicals that drive inflammation and damage.

Senescent cells can form due to DNA damage from oxidative stress, radiation, or even normal cell division. Cells lose bits of DNA each time they make copies of themselves, and they have intricate mechanisms to decide when it becomes a "bit too dangerous to keep dividing," de Maeyer said. If a cell can no longer divide, it usually undergoes a process called programmed cell death or becomes senescent, he said.

Senescence can be beneficial in some contexts; it helps heal wounds, for example. But an accumulation of senescent cells is linked to damaging inflammation and impaired organ function.

"If there are many senescent cells in a tissue, that's usually a bad sign," de Maeyer said. The number of senescent cells goes up with age and is linked to many age-related conditions, such as heart disease and dementia.

Slaying zombies

Studies in mice have shown that using drugs to kill senescent cells can reverse inflammation and some signs of cellular aging. These drugs, called senolytics, force senescent cells to enter programmed cell death, thus reducing their numbers, said Jure Povsin, a biochemist at the Max Planck Institute of Biochemistry in Germany. This ultimately reduces inflammation and improves tissue function, he told Live Science.

But while senolytics can help rid the body of zombie cells, it's not clear why the immune system fails to eliminate senescent cells in the first place. To find answers, scientists began looking at macrophages, the cells tasked with devouring dying cells.

Research pointed to a receptor on macrophages called EP2. One study, published in July in the journal Science, found that old macrophages have a greater number of these receptors and cannot eat senescent cells effectively.

Genetically deleting the EP2 receptor in lab mice restored the macrophages' function and reduced the number of senescent cells. Compared with normal mice of the same age, the genetically tweaked mice showed less cognitive decline, muscle loss, cardiac dysfunction and systemic inflammation.

On some of these metrics, such as the ability to remember familiar objects, the modified mice were comparable to younger mice.

A problem with energy

Why is the EP2 receptor at the root of this problem? Scientists found a clue in a huge study of older adults.

A molecule called PGE2 plugs into the EP2 receptor. It's a type of prostaglandin — a molecule that helps cells communicate during stress and injury and contributes to fever, pain and swelling. Drugs such as ibuprofen reduce inflammation by blocking prostaglandin production.

In 2001, a large study uncovered a connection between these prostaglandin-blocking drugs and Alzheimer's disease: People ages 55 and older who routinely took the drugs for at least two years had a lower risk of developing Alzheimer's than nonusers did. The study could not prove that the drugs directly prevented the disease, but it added to growing evidence that inflammation related to EP2 activity plays a role in Alzheimer's.

This caught the attention of Dr. Katrin Andreasson, a neurologist at Stanford University and co-author of the recent Science study.

"I thought, 'Wow, this is interesting,'" she told Live Science. "I wondered if there's a connection."

Andreasson and colleagues had an important breakthrough in 2021: They found that aging macrophages had higher levels of the EP2 receptor and that increased EP2 activity disrupted how the cells used their energy. Instead of burning glucose to produce energy like young macrophages do, these cells stashed it away.

As a result, the cells could not do their job properly, as "gobbling up cells requires a ton of energy," Andreasson said. Blocking the EP2 receptor restored normal energy use in the macrophages. In old mice, it also led to reduced inflammation and better scores on cognitive tests, compared with mice in which EP2 activity remained high.

Making senescent cells vulnerable

In their recent study, Andreasson's team uncovered another consequence of aging: Old mice accumulated many senescent neutrophils, a type of short-lived immune cell that acts as the body's first line of defense against germs. Neutrophils normally die within days and are then cleared away, but with age, they become more prone to senescence and accumulate.

"I think that's kind of an odd concept because they're [usually] very short-lived cells," said de Maeyer, who was not involved in the Science study. "Neutrophils are inherently quite inflammatory, so wanting to clear them from tissues is very valuable."

Old mice have too much EP2 activity in their macrophages, and that means they can't get rid of these neutrophils, Andreasson's team found. That may be why deleting EP2 seems to have anti-aging effects in multiple organs, they concluded.

But increased EP2 activity is just one side of the story; some studies suggest that zombie cells actively suppress macrophages' ability to eat them. They do this by using a tricky protein called CD47.

CD47 is a "don't eat me" signal that stops macrophages from destroying cells, Povsin said. "It signals that the cell is healthy, alive and doesn't need to be eaten."

However, that signal gets amplified in senescent cells, Max Planck researchers showed in a 2023 study. That means that, when macrophages interact with senescent cells, macrophages' function becomes impaired. Afterward, they even lose the ability to engulf dying, nonsenescent cells. This allows a ton of cellular debris to accumulate.

So, rather than just blocking EP2, it could also be beneficial to reduce that "don't eat me" signal in senescent cells, this research hints. But CD47 is found on all living cells, so scientists can't just deplete its numbers across the body.

A specific enzyme modifies CD47 on senescent cells, and in the 2023 study, blocking the enzyme helped spare macrophages from the effects of CD47. Therefore, blocking the enzyme could be a more selective approach to weaken the "don't eat me" signal on senescent cells, Povsin said.

A long road to treatments for people

Translating these ideas into anti-aging treatments for humans would be a major success in the science of aging, but experts say there are significant problems to overcome.

Although blocking EP2 had consistent results in lab mice, the rodents are genetically identical and bred in controlled environments. Humans are inherently more variable in their biology and the environmental factors they're exposed to, introducing confounding factors that would need to be addressed, de Maeyer said.

Additionally, in clinical trials, EP2-blocking drugs have so far been explored as cancer treatments, but they are "underexplored" in the context of aging, he added.

Drugs targeting CD47 are in an even earlier stage of development. In the 2023 research from Max Planck, the team used both human and mouse macrophages in their experiments, but the approach has not been tested as an anti-aging treatment in living mice or humans yet.

In 2020, de Maeyer's team used a different strategy to rejuvenate macrophages in older adults. They blocked a protein called p38, whose activity was high in the macrophages of older adults. Blocking the protein helped macrophages better recognize and eat dying cells in specific tests.

In that study, the team gave adults ages 65 and up an experimental drug called losmapimod to block p38. Although it helped restore their immune cell function, it was not suitable for long-term use because it caused liver problems in later trials, de Maeyer said.

In their mouse studies, Andreasson's team was able to block EP2 without causing any negative side effects. But she cautioned that we "really need to drill down on the research and confirm all this stuff in humans."

"The next logical step," she said, "would be to figure out how to inhibit this receptor in a safe way."

This article is for informational purposes only and is not meant to offer medical advice.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

The animal kingdom has influenced several robot designs over the years to solve fundamental challenges in propulsion and movement — from horses to insects. Now, frogs are the latest creatures to inspire roboticists.

As seen in a new study published Sept. 18 in the journal Science Advances, researchers probed how twisting bent elastic rods could produce a "snapping motion" that enabled a small robot to hop or swim. This mechanism could be used to improve robots with limited power and ones that need to traverse rough terrain and even water, the scientists said in the study.

They also built a prototype to demonstrate the work. The palm-sized robot weighs just 3.4 ounces, or about as much as a deck of playing cards. It moves about three body lengths per second — launching itself forward with short jumps.

"The broader opportunity is to let the mechanics of the robot do some of the work that would otherwise require larger motors or more complicated control," Xiaonan (Sean) Huang, an assistant professor of robotics at the University of Michigan and co-first author of the study, said in a statement.

"By programming when an elastic structure stores and rapidly releases energy, we can give small robots access to powerful, repeatable motions without continuously demanding high output from the motor," Huang explained. "In the future, this principle could be useful for robots that must navigate cluttered terrain, overcome obstacles, reorient quickly, or operate across both land and water."

Snap movements

When a flexible rod bends and its ends are rotated, it can eventually reach a point where it changes shape to release built-up tension, the roboticists said. However, this change does not always happen in the same way. Some combinations of bending and twisting cause the rod to change shape gradually, while other combinations force it to snap rapidly from one shape to another, with the potential to provide a strong push.

The team used computer modeling and experimentation with a robotic arm to repeatedly deform the rods and find an optimal shape. In this case, they settled on a helix similar to a coiled spring to give the rod its maximum release of energy, the team reported.

With the ideal propulsion mechanism, the team then designed and built real robots that used the snapping rods to hop. They connected these rods to a rotating motor, with the bent rods twisted until they produced the snapping motion. Then, the motor unwound the twist and contorted the rod again.

"Because the design rules depend on the rod’s shape and how its ends are moved, they work across different sizes and scales," Khalid Jawed, an associate professor at UCLA's School of Engineering and co-first author of the study, said in the statement.. "This opens a promising path toward miniaturized robots just a few millimeters in size that turn small motor movements into powerful bursts of motion," said Jawed, whose lab worked on the simulation and robot arm experiments.

The final form of the prototype was a frog-like robot with a pair of snapping rods at the rear of its main body. Tests included hopping over a broad range of surfaces, including solid materials like wood and glass, as well as trickier soft and slippery surfaces that used materials like leather. The scientists also tested the robot outdoors on sand and grass, noting that it could even climb and descend steps and, with paddle attachments, swim.

By using only one of the snapping rods, the team enabled the robot to turn and, with a remote control, navigate a small obstacle course.

Researchers have observed the strongest candidate yet for a "microblazar" — a dazzling object that has long been predicted to exist but never spotted.

Observations of microblazars would give astronomers closer views of black holes emitting powerful jets of energy and help them understand how these extreme objects behave.

Blazars are some of the most energetic objects in the universe. They are a type of quasar — a brightly glowing object fueled by a supermassive black hole stripping material from its host galaxy and then ejecting some of it in powerful, opposing jets of particles and radiation. To qualify as a blazar, one of those near-light-speed jets needs to point directly at Earth. Astronomers have previously discovered smaller versions of quasars, dubbed microquasars, and long theorized that there must be smaller versions of blazars as well.

Now, an international team led by astronomers in Spain, the Netherlands and Argentina has described a microblazar in a study accepted for publication in the journal Astronomy and Astrophysics.

"It is the first time that we have a serious candidate," Josep Martí, an astronomer at the University of Jaén in Spain and first author of the study, told Live Science.

The object, called IRAS 18293-0941, is located in our galaxy, about 12,000 light-years from Earth, and it's hidden behind a veil of dust. It is a binary system that includes a black hole that orbits a hot, gigantic star every 11 days. Matter from the star falls into the black hole, and some of this material is jettisoned into the surrounding environment in two opposing jets. One of those jets flares toward Earth.

These objects, as well as microquasars in general, are tricky to observe, Martí said. "Because of stellar evolution, you need to catch the system at the right time," he added. "The microquasar phase of evolution is very short, and so it is difficult to find one in that phase."

Theorists predicted that microblazars would have special characteristics that should help define them. These features include powerful emissions across the electromagnetic spectrum, rapid changes in brightness (variability), and a hotspot behind them where its opposing jet heats up the interstellar medium in the opposite direction of Earth.

To observe IRAS 18293-0941, the study authors used a variety of instruments ‪—‬ including the Calar Alto Astronomical Observatory in Spain, a network of radio astronomy telescopes called the European VLBI Network, and the MeerKAT radio telescope array in South Africa ‪—‬ as well as archival data from the Very Large Array in New Mexico.

They found that IRAS 18293-0941 has all of the expected microblazar characteristics, except one ‪—‬ variability. Microblazars have rapid variability, which means their brightness changes a lot in a short period, because one of the jets is facing Earth and small changes in brightness are amplified by an effect called Doppler boosting.

Martí said IRAS 18293−0941's lack of rapid variability could be explained by the dense cloud of gas surrounding it, which could smooth out quick fluctuations in brightness.

The researchers are currently investigating whether the observed area behind the microblazar is in fact a hotspot, study co-author Pedro Luque-Escamilla, an astronomer at the University of Jaén, told Live Science.

Even with one of the expected features missing, this object is a promising candidate for the first known microblazar. "The claims and the results of the paper are sensible and there are no questionable hidden assumptions," Kinwah Wu, a theoretical astrophysicist at University College London who was not involved in the research, told Live Science in an email. "The source in this paper had shown signatures of interactions between the jets and the ambient material, which naturally leads to [particle] interaction."

Svetlana Jorstad, a senior research scientist at the Institute for Astrophysical Research at Boston University who was not involved in the research, told Live Science in an email that the new study was "very interesting, important and comprehensive."

Itumeleng Monageng, an astronomer at the University of Cape Town who was also not involved in the research, added that the team's observations "presents a previously overlooked mechanism for generating some of the highest energy emissions observed."

Microblazars "may power some of the universe's most energetic processes," Monageng told Live Science in an email.

Martí, J., Luque-Escamilla, P. L., Marcote, B., Abaroa, L., Aguasca-Cabot, A., Combi, J. A., Romero, G. E., Paredes, J. M., García, F., Fogantini, F., Saavedra, E. A., Del Ser, D., & Van Den Eijnden, J. (2026). A Galactic microblazar as a potential accelerator of ultra-high-energy particles. Astronomy and Astrophysics. https://doi.org/10.1051/0004-6361/202661105

See how much you know about black holes with our black hole quiz!

Archaeologists have unearthed evidence that men, women and children were subjected to violence within their communities in ancient Scandinavia — and that these victims were buried in unusual places, such as pits or wells or under a family's house or yard.

During the Scandinavian Iron Age and Viking Age (from roughly 500 B.C. to A.D. 1050), violent encounters between individuals and communities steadily increased, resulting in archaeological evidence of elite warrior burials and mass graves from battles.

To better understand the context of violence in the Iron and Viking ages, researchers analyzed 192 human bones from people buried in domestic areas at settlements in what are now Denmark, Norway and Sweden.

"The fact is that not all bodies ended up in monumental burial mounds in the Iron and Viking Ages, or even in more modest urnfields and cemeteries," the researchers wrote in a study published Sept. 28 in the Journal of Archaeological Method and Theory. Rather, some bodies — or pieces of bodies — were placed in postholes, pits, floors, wells, houses, yards and feasting halls.

The archaeologists discovered that at least 12 of the individuals had sustained a violent injury around the time of death. Half of those cases involved head trauma, while four people suffered multiple injuries. Most of the victims of violence were adult males, but there were two females and a child as well.

In one Iron Age house in Denmark, built sometime between 500 and 1 B.C., archaeologists discovered a frontal bone from the skull of a child who died between the ages of 2 and 4 years old.

"Our DNA analyses show that it is a small boy who has been cut with a sword," study first author Marianne Hem Eriksen, an archaeologist at the National Museum of Denmark, said in a translated statement. "The child's skull was placed on the floor of a house where people continued to live. This means that someone has walked over a child's skull day after day."

Radiocarbon dating revealed that the child's skull is significantly older than the house itself, by as many as two centuries, suggesting the bone may have been kept for some time before being placed in the house floor, according to the study.

At a Viking Age site dated to around 750 to 1050, archaeologists found a young woman's skull in a well near a cluster of four small houses. "The woman's skull bore traces of blows and was buried in a well," Eriksen said. She may have been cut or slashed with a sword or ax and, like the child, her bones may have been kept for a significant amount of time before being buried in the well. "These glimpses of lives lived from the past show how fascinatingly different people must have thought about life and death," Eriksen said.

And at the Viking Age site of Gammel Lejre, a royal feasting hall that many experts consider to be the inspiration for the epic Old English poem "Beowulf," archaeologists found the burial of a man whose skeleton bore numerous blunt force injuries, several of which had healed, and which attested to a difficult and likely painful life. His skeleton was discovered directly south of the feasting hall.

The study of bones in domestic areas "opens up a completely new understanding of Iron Age society, of the occurrence of violence and of the handling of the dead," Eriksen said. "The results show a much greater complexity in the everyday life and world of imagination of the time than we often attribute to Iron Age people."

But it is unclear exactly why these particular people were the victims of violence and why they were buried in such unusual ways. One possible scenario, the researchers wrote in the study, is that these were victims of violent domestic encounters rather than warfare. Their deaths may also have been the result of socially acceptable corporal punishment or some form of aggression within the community.

Given the increase in social inequality and rise in violence in the Iron and Viking ages, the researchers suspect that precarious community members may have been targeted.

"Not all lives were equally grieved and commemorated in the Iron and Viking Ages of Scandinavia," the researchers wrote. "We may question whether some lives were already considered disposable."

See how much you know about ancient norsemen with our Viking quiz!

Rosalind Franklin, whose photographs of the molecular structure of DNA led to a 1962 Nobel Prize for three other scientists, knew that her famous images held the secret of the double helix, new research suggests.

An examination of archival material reveals that Franklin's Photograph 51, which was taken in May 1952 and later published to show the double-helix structure, was specifically taken for the purpose of publication — not, as some narratives have held, an experimental shot that Franklin believed was insignificant. The new research revealed that Photograph 51 was a new exposure of a sample Franklin had already photographed. She started Photograph 51 the same day she saw that photograph, Photograph 49.

"She took it because she wanted to get a really refined version," said study co-author Alistair Sponsel, a historian of science at the Science History Institute in Philadelphia. Making the effort to take a better photograph of the same sample is "a sign she knew she had something really important on her hands," Sponsel told Live Science.

Francis Crick, James Watson and Maurice Wilkins shared the Nobel Prize in Medicine for the discovery of the double-helix structure of DNA in 1962. As Watson told it in his 1968 autobiography, "The Double Helix: A Personal Account of the Discovery of the Structure of DNA," Franklin's photographs were his "aha" moment: "The black cross of reflections which dominated the picture could only arise from a helical structure," he wrote.

Watson further implied that Franklin was a laboratory automaton, good at the X-ray crystallography techniques used to capture the images of the DNA molecule but bad at interpreting her own data. The new archival work, published Monday (Oct. 5) in the Journal of the History of Biology, suggests otherwise.

Franklin's dearth of published notes about Photograph 51 has been used to suggest she missed a major discovery. But Sponsel said her journals show she noted the possible helical shape and rich structural data in her notes for her first picture of the sample, Photograph 49, which she followed up with the more refined image in Photograph 51.

"In Franklin's mind, they were two different types of scientific image," Sponsel said. Photograph 49 was the experimental image revealing exciting new data. Photograph 51 was the showpiece to convey these findings with the most clarity and sharpness possible.

This new understanding of the relationship between the two images, and how Franklin perceived them, is the most important feature of the new work, Sponsel said, which he conducted with molecular biophysicist Brian Sutton of King's College London. The project began when the Science History Institute acquired a new collection of archival material from Rosalind Franklin and her graduate student Raymond Gosling. The two researchers also combed through the archives at King’s College London, where Franklin was working when she took the famous photos.

Sponsel and Sutton think that Franklin's notes and actions reveal why she didn't rush to publish Photograph 51 right away. Her scientific goals, laid out in a report she wrote in February 1952, were to understand the two separate structures of DNA, then known as A and B. Structure B, illustrated in Photographs 49 and 51, turned out to be the double helix that occurs in nature. Structure A is a form DNA takes when it's dehydrated in the lab.

Structure A, when photographed, appeared more data-rich, so Franklin decided to characterize that structure first before studying structure B. But while she did this painstaking work, Wilkins showed Watson her photographs of structure B. The two scientists, together with Crick, then built a detailed model of DNA's double helix and scooped the discovery from under her nose.

Those three men shared the Nobel Prize for the work less than a decade later. Franklin died of ovarian cancer in 1958, making her ineligible for the prize — and leaving her insights to come to light only much later.

Editor's note: This article was updated at 3:23 p.m. ET to fix the caption and subhead, noting that Rosalind Franklin had likely discovered DNA's helical, but not double-helix structure. Also, the top photo is not Photograph 51, but another photo taken by Franklin.

Mpox spread across the world in 2022, triggering tens of thousands of cases in countries where the infection was once rarely seen. Although the disease has since fallen out of news headlines, mpox (formerly called monkeypox) continues to circulate. Now, recent data suggests that the viral illness may soon be endemic to the United States, meaning it will circulate in the country consistently.

Previously, mpox cropped up sporadically in the U.S. via travelers who had visited African countries where the disease is endemic, as well as imported, infected animals that spread the virus to people. Cases have fallen substantially since the peak of the outbreak in 2022, but they haven't disappeared. A report published in August found that there were 2,800 cases in 2024 and over 2,500 in 2025, with only a small fraction being tied to travel. Nearly all of the viral samples analyzed were descendants of the strain that sparked the 2022 outbreak. In short, once the virus arrived, it never went away.

"There's no set threshold for what constitutes endemicity of monkeypox virus (MPXV) in the United States," Ryan Standford, an epidemiologist in the Centers for Disease Control and Prevention's (CDC) Poxvirus and Rabies Branch and co-author of the report, told Live Science in an email. "But each year provides further evidence of this transition."

Why is mpox still spreading in the U.S., and what can be done to snuff it out? It's likely that too few people have received two doses of the mpox vaccine JYNNEOS, which together are 66% to 90% effective. But beyond low vaccination, there may be other, less-understood factors that are contributing to the continued spread, experts told Live Science.

"We don't quite know how it's able to persist at such low numbers across the entire country," said Joel Wertheim, a professor of medicine in the Division of Infectious Diseases and Global Public Health at the University of California, San Diego.

At the same time, public health efforts around mpox have dwindled. Without a sustained effort on that front, it's unlikely the disease will be eliminated from the U.S.

"We have vaccines, testing, and a much stronger understanding of the disease than we did in 2022," Dr. Demetre Daskalakis, chief medical officer of Callen-Lorde, a LGBTQ+ community health center in New York City, told Live Science in an email. "Our focus now should be making sure those tools remain accessible, especially for communities that continue to face ongoing risk," said Daskalakis, who coordinated the nation's mpox response during the previous presidential administration.

"People at increased risk should know that mpox has not disappeared."

Who is at risk of mpox in the U.S.?

In the U.S., mpox is predominantly affecting men who have sex with men, and current vaccine recommendations are aimed at this group and their sexual partners. Mpox mostly spreads from person to person through close contact, and transmission during sex is playing a major role in the ongoing spread in the U.S.

Men who have sex with men are not more prone to mpox infection than anyone else. Rather, this transmission pattern stems from the outbreak beginning within a specific sexual network and then continuing to persist within the same network. "The mpox virus rediscovered the same transmission network that HIV had explored decades earlier," Wertheim said.

In a paper published in 2025, Wertheim and colleagues described the transmission dynamics of mpox in New York City during the 2022 outbreak. Similar to how HIV previously spread, mpox triggered "densely connected" clusters of infection. Then, as people in the network gained immunity via infection and vaccination, the cases petered out, decreasing to the persistent trickle we see now.

Wertheim noted that he's not surprised that mpox has remained largely confined to the same network, rather than leaping into new groups.

"From an evolutionary, ecological perspective, it's not hugely successful," Wertheim said. "It's sort of barely hanging on as an STI."

Why is mpox still circulating?

So if mpox is not hugely successful and we have a vaccine, how has the virus continued to circulate? One big factor is that too few at-risk people have been vaccinated, experts said.

The CDC's Center for Forecasting and Outbreak Analytics has crunched the numbers to see what percentage of that at-risk group needs to have immunity to stop mpox transmission, Daskalakis said. The at-risk group is estimated by counting the men who have sex with men who are either taking HIV-preventing medicines or have HIV, and then adding 25% to that total to account for additional people in the same sexual network. That estimate comes out to about 2 million people.

To prevent an outbreak bigger than the one in 2022, between 21% and 35% would have to have immunity through vaccination or a past infection. If over 50% of the group had immunity, that would mean there's a "very small probability" of sustained local transmission, the CDC's modeling suggested.

The current case counts suggest we haven't hit the 50% mark, or a total of roughly 1 million complete vaccinations or past infections.

Data from the August report on mpox seems to support the idea that too few people are vaccinated. That said, information about vaccination status was missing for about 62% of the reported cases. Among the remaining cases, 76% were unvaccinated, while 10% had gotten one dose and 14% had gotten two.

In a subset of 860 cases, the effect of vaccination was striking: Unvaccinated people had nearly 10 times higher odds of hospitalization due to mpox than fully vaccinated people did.

Waning public health attention

It's difficult to pin down exactly how many at-risk people are vaccinated, given that that data is no longer tracked at the national level. "My understanding is that there's no mandatory reporting on mpox vaccination data," Wertheim said.

The CDC previously monitored national vaccination trends, comparing the number of people vaccinated to the overall at-risk population. But that tracking stopped in early 2024, when about 23% of the at-risk population had been fully vaccinated.

Some states, such as New York, previously mandated that clinicians provide their state health department data on the number of people given mpox vaccines. But that reporting is now voluntary, a spokesperson for the New York State Department of Health told Live Science in an email.

Meanwhile, "as the emergency phase faded from public attention, awareness and risk perception may have declined," Daskalakis said. Public health messaging about the virus and vaccination has also waned.

"In recent weeks, HHS [the Department of Health and Human Services] has pulled down some of the plain-language guidance, which is not helpful in supporting messaging," Daskalakis noted. This decision to remove online resources about mpox reflects the federal government's current stance against addressing issues that affect LGBTQ+ health, he told Live Science.

Complicating factors

Although JYNNEOS substantially lowers the risk of severe mpox infection, the vaccine is not perfect, said Rachel Roper, a professor of microbiology and immunology at East Carolina University.

The virus typically enters the body through broken skin, the respiratory tract or mucous membranes (thin tissues found in the eyes, nose, mouth, anus and genitals). The mpox vaccine is good at generating systemic immunity, but it's not as good at guarding against the virus's immediate effects at those mucous membranes, said Roper, who studies poxviruses and vaccines against them.

Because mpox is largely spreading through sexual contact that involves those membranes, that slight gap in protection may also help to explain some of the ongoing spread, she suggested.

Plus, "there are also some data supporting asymptomatic infection as a possible route of transmission, making it more difficult to eliminate local transmission of mpox," Daskalakis said.

What can be done?

Given that mpox is already well established within some sexual networks in the U.S., "preventing endemicity entirely may be increasingly difficult," Standford told Live Science.

And notably, some federal funding cuts could undermine efforts to address mpox, Daskalakis said. These include cuts to Medicaid, mental-health services, housing programs, and HIV services such as the Ryan White HIV/AIDS Program.

Thankfully, looking at current mpox trends, "there's no indication we're returning back to 2022 levels," Wertheim told Live Science. So far in 2026, just under 1,000 mpox cases have been reported, according to the CDC. Month over month, the number of cases is generally trending downward. So, at a glance, the current situation seems better than it was in 2025, he said.

"We sort of seem to be on this razor's edge between endemicity and extinction," he said. "And it's not really clear which way it'll go."

Tipping the virus toward extinction will require healthcare providers to be informed and equipped to spot and manage cases, Daskalakis said. And communicating the importance of vaccination is key.

"One lesson from 2022 was that trusted messengers matter," he said. "We [at Callen-Lorde] work closely with LGBTQ+ communities and make information and vaccination opportunities available in settings where people already receive care." The clinic integrates conversations about mpox vaccination into routine health visits, sexual health services, HIV prevention programs and community outreach activities.

Beyond vaccinating at-risk populations, educating patients about how mpox spreads and how to reduce their risk is also key, Standford noted. "Vaccination coverage is a very important factor, but it is not the only one," he said.

Tipping mpox toward extinction will also require enough investment to maintain the disease surveillance, vaccination, testing and treatment capacity that the federal government helped to expand in 2022, Daskalakis said. The vaccine itself is now commercially available to clinics and in adequate supply, he emphasized.

"The fact that we're seeing ongoing circulation underscores the need for sustained prevention efforts rather than viewing mpox as a resolved public health issue," he said. "Infectious diseases don't disappear simply because public attention shifts."

This article is for informational purposes only and is not meant to offer medical advice.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

On Sept. 20, the Antarctic ozone hole peaked at 10.6 million square miles (27.4 million square kilometers), the second-largest size ever observed for this time of the year.

The last time the ozone hole was this big was in October 2015, when it reached a whopping 10.8 million square miles (27.9 million square km), records from the Copernicus Atmosphere Monitoring Service show. So why is the hole in the ozone layer — the shield that protects life on Earth from harmful ultraviolet solar radiation — so big this year, despite other clues telling scientists that it is recovering as expected from the damage human-made chemicals did in the 20th century?

The ozone hole's extent is due to extremely low temperatures in the stratosphere, but it's also possible that we could be seeing a new long-term trend of large, persistent holes, experts told Live Science.

"This year's ozone hole shouldn't be a cause for alarm," Hannah Kessenich, a postdoctoral physicist at the University of Otago in New Zealand who predicted the 2026 ozone hole's extent using satellite data and a computer model, told Live Science in an email. "However, there are still many unanswered questions. It's something we need to keep a close eye on."

Accurate predictions

The latest figures from the Copernicus Atmosphere Monitoring Service indicate that the size of Antarctica's ozone hole has dropped to around 8.9 million square miles (23 million square km) since Sept. 20, making it unlikely that this year will break the 2015 record. However, scientists think the hole will remain large and fluctuate over the next few weeks, Kessenich said.

Antarctica's ozone hole expands every year during the Southern Hemisphere's winter and spring. It typically reaches its maximum size between mid-September and early October, when temperatures are still freezing in the stratosphere and sunlight illuminates the frozen continent for the first time after months of darkness. The hole then shrinks again until late January as surrounding ozone-rich air mixes into the depleted region.

Antarctica's ozone hole was caused by emissions of ozone-destroying chlorofluorocarbons (CFCs) between the 1930s and late 1980s. These chemicals increased concentrations of chlorine in the stratosphere, thereby promoting a reaction that depletes the ozone layer. While countries signed the Montreal Protocol to phase out CFC use beginning in 1989, major CFCs have atmospheric lifetimes of 50 to 100 years, so the hole's recovery could take six decades, researchers estimate.

The ozone layer is particularly vulnerable above Antarctica due to the frigid conditions in the polar stratosphere. Temperatures below minus 108 degrees Fahrenheit (minus 78 degrees Celsius) trigger the formation of high-altitude clouds, whose icy surfaces turn inactive chlorine into its ozone-destroying form in the presence of sunlight. These conditions don't exist to the same extent in the Arctic, because warmer air from the midlatitudes mixes more readily with cold Arctic air than with Antarctic air, thereby blocking the formation of high-altitude clouds.

Changes in the polar vortex

This year's large ozone hole is caused by a very strong polar vortex, a wall of wind that encircles Antarctica and the Southern Ocean in the winter, trapping cold air above the continent. The polar vortex created colder-than-usual conditions in the stratosphere over Antarctica, accelerating the growth of the ozone hole.

Researchers haven't detected an increase in reactive chlorine, but the colder polar vortex has triggered more ozone depletion than usual, said Susan Solomon, a professor of chemistry and environmental studies at MIT who pioneered the study of Antarctica's ozone hole in the 1980s.

This size of this year's ozone hole is most likely a product of natural variability in atmospheric dynamics, Kessenich said.

"We expect ups and downs in the size of the hole from year to year," Solomon told Live Science in an email. "A year or a few years of bigger or smaller holes doesn't tell us anything about ozone loss or recovery; it is just variability. We have to look at the longer term trends, and those metrics continue to tell us that the ozone hole is slowly recovering as expected."

It's also reassuring that the ozone hole, while large, isn't as "thin" as in years past. The hole's extent is calculated based on the area above the continent with ozone values below 220 Dobson units, a measure of how many ozone molecules occur in a vertical column through Earth's atmosphere. Although the area of this year's ozone hole is huge, ozone values haven't dropped as low as in previous big-ozone-hole years, suggesting that there is less ozone "missing" from the hole compared with those years, Kessenich and her colleagues wrote in The Conversation.

But there's also the possibility that we've shifted to a new long-term trend of big ozone holes persisting until late spring, Kessenich said. Changes in global atmospheric dynamics unrelated to CFCs could be making longer-lived holes more likely, she and her colleagues wrote in the article.

There is also some evidence that climate change will strengthen the Antarctic polar vortex over time, which could lead to colder temperatures in the stratosphere and greater ozone losses in the spring, Kessenich said. If this year's polar vortex stays robust, the ozone hole could remain large well into November, she noted.

"It's too soon to tell what has been driving dynamical variability in recent years, but more research is needed," she added.

Help us improve Live Science Pro: We're always trying to make our content better. Leave us feedback about Pro here.

Mpox is an infectious disease caused by a poxvirus, meaning a virus in the same family as smallpox. The infection was formerly known as monkeypox.

Historically, mpox was endemic to Africa, and the virus consistently spread in the continent's central, eastern and western regions. In 2022, an unprecedented global outbreak spurred the widespread transmission of mpox in places that had seen only sporadic cases in the past.

Today, many countries affected by that outbreak — including Germany, Portugal and the United States — are still contending with local mpox transmission. Here's what to know about the virus, how it spreads and how to prevent infection.

What to know about mpox in the U.S.

Mpox is still spreading at low levels in the United States and may soon be considered endemic to the country. While case counts have fallen dramatically since the peak of the global outbreak in summer 2022, some people are still advised to get vaccinated against the virus.

Who should get vaccinated for mpox?

The mpox vaccine currently used in the U.S. is called JYNNEOS. One dose is about 35% to 86% effective, while the complete two-dose series is 66% to 90% effective. (The effectiveness varies, in part, because some studies include people with HIV and people without HIV, and inadequately treated HIV can undermine the body's response to vaccines.)

The JYNNEOS vaccine is not currently recommended for routine use in the general population because, beyond vulnerable groups, the risk is not high enough to warrant a universal vaccination strategy. The current outbreak is primarily affecting men who have sex with men, and those sexual networks are the primary targets for JYNNEOS vaccination.

However, not all men who have sex with men need to be vaccinated, according to the Centers for Disease Control and Prevention (CDC). Instead, vaccination is recommended for a specific subset of the group, including those who, in the last six months, have had more than one sex partner, have had sex at commercial sex venues, or have been diagnosed with other sexually transmitted diseases.

Nonbinary and transgender people with these risk factors are also recommended to get two doses of JYNNEOS, as are any sexual partners of anyone in the above groups.

Vaccines are also recommended after a suspected exposure to mpox, as they can help prevent or reduce the severity of the infection.

"For those who are eligible and have not yet completed vaccination, now is a good time to talk with a healthcare provider about getting protected," Dr. Demetre Daskalakis, chief medical officer of Callen-Lorde, an LGBTQ+ community health center in New York City, told Live Science in an email.

With the exception of laboratory researchers who work with mpox, people who have received two doses of JYNNEOS are fully vaccinated and do not need a booster, he said. And if a person has caught mpox in the past and recovered, they do not need to get a vaccine, he added.

About the virus

The poxvirus family also includes smallpox, which has been eradicated worldwide. Mpox and smallpox cause some similar symptoms, but mpox tends to be far milder than smallpox. However, the viruses are closely related enough that vaccines designed to prevent smallpox can also protect against mpox.

Mpox was initially named monkeypox because the virus behind the disease was discovered in captive monkeys in Denmark. But monkeys are not the main hosts of the virus in the wild; rodents and small mammals mostly found in West and Central Africa likely are. Health officials changed the name to mpox in 2022.

There are two major branches of the mpox family tree, called clade I and clade II. These clades were historically thought to have very different death rates, with clade I being the deadlier of the two. The case-fatality rate (CFR) of clade I has been estimated to range from 1.4% to over 10%, depending on the outbreak, while the CFR for clade II has been estimated at between 0.1% and 3.6%.

However, as both clades have spread beyond Africa, data suggests that the CFR for clade I may be lower than once thought, said Joel Wertheim, a professor of medicine in the Division of Infectious Diseases and Global Public Health at the University of California, San Diego.

The features of a given outbreak — such as the surrounding health infrastructure, patients' access to timely medical care, and the population's underlying risk factors for severe disease — likely play a big role in determining the virus's death toll, Wertheim told Live Science. In short, rather than being an immutable feature of the virus itself, the CFR is dependent on the underlying health of and resources available to a given population.

How mpox spreads

Mpox can spread from infected animals to humans through the animals' bites or scratches. Additionally, people can get the virus when they come into close contact with animals and/or their bodily fluids during hunting, skinning, trapping, cooking, eating animals or handling carcasses, the World Health Organization (WHO) notes.

The virus also spreads from person to person, primarily through very close contact, including intimate contact during sex. The virus typically enters the body through broken skin, the respiratory tract or mucous membranes (thin tissues found in the eyes, nose, mouth, anus and genitals), spreading via bodily fluids such as spit, mucus or blood. People can also pick up the virus via objects, such as clothing or linen, that are contaminated with the bodily fluids of an infected person.

The virus can spread through small respiratory droplets expelled during speaking or breathing. However, this is thought to be a less-common transmission route than close contact. There is also evidence that asymptomatic spread sometimes occurs, though it's unclear how frequently that happens.

Mpox can spread from mother to baby during pregnancy or birth. This route of infection can result in pregnancy loss, stillbirth, death of the newborn, or complications for the mother.

Symptoms of mpox

Symptoms of mpox typically appear within a week of a person being exposed to the virus, but they can sometimes take up to 21 days to develop. Once they emerge, symptoms last about two to four weeks, although the illness can linger longer in people with weakened immune systems.

Common symptoms include rash (see images), fever, sore throat, headache, muscle aches, back pain, swollen lymph nodes and low energy. Often, mpox rashes first appear on the face and then spread to other parts of the body; however, if a person becomes infected during sex, the rash may instead start around their genitals. The rashes begin as flat, discolored patches of skin and then progress into raised bumps, blisters, and large, pus-filled pimples that eventually scab over and fall off.

Some people with mpox develop painful swelling of the rectum (proctitis), while others have pain and difficulty when peeing (dysuria) or when swallowing.

Mpox rashes can make people vulnerable to bacterial skin infections, which can cause abscesses or other serious skin damage. Additional complications of the illness include pneumonia, infection of the cornea that can cause vision loss, and vomiting and diarrhea that causes dehydration or malnutrition. Mpox can also lead to blood infections, the intense immune reaction sepsis and, rarely, brain infections (encephalitis) or heart inflammation (myocarditis).

Children, pregnant people, and people with weakened immune systems, including from HIV infection, have a higher risk of serious illness and death from mpox.

Mpox prevention measures

Beyond vaccination, other strategies to decrease the risk of mpox infection include washing hands frequently, avoiding contact with contaminated objects and materials used by people with mpox, avoiding contact with other people's scabs or rashes, and using condoms, although they may only reduce, not eliminate, the risk of mpox exposure during sex.

Mpox treatment

Mpox treatment aims to manage a person's rashes and pain while also preventing complications. "Early and supportive care is important to help manage symptoms and avoid further problems," according to the WHO.

There is no antiviral drug approved for use in mpox, although some are available for emergency use in various countries. For example, the U.S. allows the use of certain smallpox medicines for mpox.

Severe mpox infections also may be treated with vaccinia immune globulin intravenous, which contains antibodies taken from the blood of people who were immunized against smallpox.

People who have recently been exposed to mpox can be given an mpox vaccine to reduce the severity of their symptoms or to prevent the illness altogether. This approach is known as post-exposure prophylaxis, or PEP.

"Post-exposure vaccine should be given as soon as possible, ideally within 4 days of exposure; administration 4 through 14 days after exposure may still provide some protection against monkeypox," the CDC states.

You may have watched the moon block out the sun during a solar eclipse, but have you ever seen it do that to a planet? Early Tuesday (Oct. 6) morning, skywatchers across much of eastern North America will have an opportunity to watch a crescent moon pass directly in front of Jupiter. The rare alignment won't happen again for 11 years.

During the event, known as a lunar occultation, Jupiter will disappear behind the moon for up to about an hour before suddenly reappearing. The occultation will be visible before dawn from much of the eastern and central U.S., Canada and the Caribbean, while parts of Africa will experience the event during daylight, according to In-The-Sky.org.

The moon will be a beautiful waning crescent, just 20% illuminated, and Jupiter will shine brightly alongside it. The pair will rise together in the east early Tuesday morning and gradually appear to move closer as the moon travels eastward against the background stars.

When the occultation begins, Jupiter will remain hidden behind the moon for roughly an hour. No telescope will be needed to watch Jupiter disappear and reappear. However, a pair of binoculars or a small telescope will make the event much more dramatic.

Through a telescope, Jupiter will look like a tiny disc rather than a point of light and will take about a minute to disappear completely behind the moon. An easy way to photograph the event is to use a smart telescope to image the moon. (Here's everything you need to know about lunar photography).

Below are the times when Jupiter will disappear and reappear in 10 major cities Tuesday morning, according to the International Occultation Timing Association.

• Chicago: 3:22-4:17 a.m. CDT
• Atlanta: 4:15-5:17 a.m. EDT
• Detroit: 4:16-5:20 a.m. EDT
• Miami: 4:20-5:09 a.m. EDT
• Washington, D.C.: 4:20-5:24 a.m. EDT
• Philadelphia: 4:22-5:26 a.m. EDT
• New York: 4:23-5:27 a.m. EDT
• Toronto: 4:25-5:22 a.m. EDT
• Boston: 4:26-5:30 a.m. EDT
• Montreal: 4:30-5:26 a.m. EDT

Outside the occultation path, Jupiter won't disappear at all. Instead, it will appear to be skimmed by the crescent moon — still a potentially spectacular sight that could produce some amazing photos. From across much of the world, the crescent moon and Jupiter will appear exceptionally close together.

The next lunar occultation of Jupiter visible from North America will occur on Nov. 27, 2037, according to When The Curves Line Up.

The ancient Egyptians practiced human sacrifice around 5,000 years ago, a period shortly after the country was first unified, a new study finds.

In the new study, Roselyn Campbell, an anthropology researcher at Purdue University, re-examined 46 skulls from individuals who were buried near royal tombs that belonged to King Djer, King Djet and Meretneith (a woman who likely ruled Egypt at times), and were built near the ancient sacred city of Abydos. All three rulers lived during the first dynasty, a period that started around 5,000 years ago when Upper Egypt and Lower Egypt were unified into one kingdom. The sacrificed retainers were buried next to the tomb of the king they had served.

Researchers first excavated the royal burial site in the early 20th century. At the time, the excavator, Flinders Petrie, believed that the hundreds of other burials found near the royal tombs contained nonroyals, such as retainers and other people who served the king. Moreover, it appeared that these nonroyals had been sacrificed after the king they had served died, in the belief that they could serve the king in the afterlife.

However, Petrie was unable to identify evidence of fatal skeletal trauma, and his idea that they were sacrificed has been debated ever since. Petrie reburied most of the human remains, but 46 skulls were retained and preserved in the Duckworth Collections at the University of Cambridge.

In the new study, published Monday (Oct. 5) in the journal Frontiers in Environmental Archaeology, Campbell re-examined these 46 skulls using modern forensic techniques and information about the marks that different types of trauma leaves on human skeletons. Campbell found that 18 of the skulls have signs of trauma that were likely fatal — indicating that these individuals were likely sacrificed, according to a statement from the journal. Specifically, Campbell found that many of the skulls had linear fractures, which Petrie had mistaken for damage that occurred after burial.

Linear fractures "occur when the cranium strikes or is struck by a relatively large object with low overall force; because of the cranium's globular shape, the impact of the blow disperses across the cranial vault," Campbell wrote in the study. "While linear fractures are not always immediately lethal, they often cause intracranial lesions and/or hemorrhage, which can quickly cause loss of consciousness and death if surgery [to relieve pressure] is not performed."

Campbell told Live Science in an email that it's difficult to identify the weapon or object that was used. "Based on comparative forensic and archaeological studies, the most likely implement would have been flat and relatively light, probably made out of something like wood rather than stone," she said.

The practice of human sacrifice seems to have ended in the second dynasty of Egypt. Evidence for human sacrifice is limited and seems to be confined mainly to the first dynasty. Petrie theorized that they were retainers to the king based on the fact that some were buried with gravestones that had titles such as seal-bearer which suggested that they served the king.

"As far as we can tell, this particular type of retainer sacrifice seems to have ended with the close of the First Dynasty, which means it [lasted] around two centuries or possibly less," Campbell said.

Jacobus van Dijk, an Egyptologist at Groningen University in the Netherlands who was not involved with the study, welcomed the new research. The "existence of retainer sacrifice in early Egypt has always been controversial and Dr Campbell's research adds an important argument in support of scholars who, like myself, believe this custom was practised in Egypt in the early dynastic period," he told Live Science in an email.

He noted he was surprised at the method used for human sacrifice, because depictions of ritual killing on wooden labels "seems to indicate that the victim was kneeling with his hands tied behind his back being stabbed in the chest with a knife."

Are you a fan of mummies and hieroglyphs? Find out with our ancient Egypt quiz!